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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50123363   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50123363
PNG
(7-Methoxy-2-(4-morpholin-4-yl-phenyl)-6-oxazol-5-y...)
Show SMILES COc1cc2nc(cc(O)c2cc1-c1cnco1)-c1ccc(cc1)N1CCOCC1
Show InChI InChI=1S/C23H21N3O4/c1-28-22-12-20-17(10-18(22)23-13-24-14-30-23)21(27)11-19(25-20)15-2-4-16(5-3-15)26-6-8-29-9-7-26/h2-5,10-14H,6-9H2,1H3,(H,25,27)
PDB
MMDB

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n/an/a 21n/an/an/an/an/an/a



Bristol-Myers Squibb PRI

Curated by ChEMBL


Assay Description
Inhibitory activity against inosine monophosphate dehydrogenase IMPDH II


Bioorg Med Chem Lett 13: 547-51 (2003)


Article DOI: 10.1016/s0960-894x(02)00945-9
BindingDB Entry DOI: 10.7270/Q2NS0T7H
More data for this
Ligand-Target Pair