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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50123365   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50123365
PNG
(7-Methoxy-6-oxazol-5-yl-2-(4-pyrrolidin-1-yl-chrom...)
Show SMILES COc1cc2nc(cc(O)c2cc1-c1cnco1)-c1ccc2OCCC(N3CCCC3)c2c1
Show InChI InChI=1S/C26H25N3O4/c1-31-25-13-21-17(11-19(25)26-14-27-15-33-26)23(30)12-20(28-21)16-4-5-24-18(10-16)22(6-9-32-24)29-7-2-3-8-29/h4-5,10-15,22H,2-3,6-9H2,1H3,(H,28,30)
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Article
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n/an/a 33n/an/an/an/an/an/a



Bristol-Myers Squibb PRI

Curated by ChEMBL


Assay Description
Inhibitory activity against inosine monophosphate dehydrogenase IMPDH II


Bioorg Med Chem Lett 13: 547-51 (2003)


Article DOI: 10.1016/s0960-894x(02)00945-9
BindingDB Entry DOI: 10.7270/Q2NS0T7H
More data for this
Ligand-Target Pair