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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50123373   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50123373
PNG
(2-((2R,3R)-3-Dimethylamino-2-methoxy-indan-5-yl)-7...)
Show SMILES CO[C@@H]1Cc2ccc(cc2[C@H]1N(C)C)-c1cc(O)c2cc(-c3cnco3)c(OC)cc2n1
Show InChI InChI=1S/C25H25N3O4/c1-28(2)25-16-7-15(6-5-14(16)8-23(25)31-4)19-10-21(29)17-9-18(24-12-26-13-32-24)22(30-3)11-20(17)27-19/h5-7,9-13,23,25H,8H2,1-4H3,(H,27,29)/t23-,25-/m1/s1
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MMDB

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Article
PubMed
n/an/a 15n/an/an/an/an/an/a



Bristol-Myers Squibb PRI

Curated by ChEMBL


Assay Description
Inhibitory activity against inosine monophosphate dehydrogenase IMPDH II


Bioorg Med Chem Lett 13: 547-51 (2003)


Article DOI: 10.1016/s0960-894x(02)00945-9
BindingDB Entry DOI: 10.7270/Q2NS0T7H
More data for this
Ligand-Target Pair