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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50123374   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50123374
PNG
(2-Imidazol-1-yl-N-[6-(7-methoxy-6-oxazol-5-yl-4-ox...)
Show SMILES COc1cc2nc(cc(O)c2cc1-c1cnco1)-c1ccc2CCC(N(C)C(=O)Cn3ccnc3)c2c1
Show InChI InChI=1S/C28H25N5O4/c1-32(28(35)14-33-8-7-29-15-33)24-6-5-17-3-4-18(9-19(17)24)22-11-25(34)20-10-21(27-13-30-16-37-27)26(36-2)12-23(20)31-22/h3-4,7-13,15-16,24H,5-6,14H2,1-2H3,(H,31,34)
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MMDB

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Article
PubMed
n/an/a 68n/an/an/an/an/an/a



Bristol-Myers Squibb PRI

Curated by ChEMBL


Assay Description
Inhibitory activity against inosine monophosphate dehydrogenase IMPDH II


Bioorg Med Chem Lett 13: 547-51 (2003)


Article DOI: 10.1016/s0960-894x(02)00945-9
BindingDB Entry DOI: 10.7270/Q2NS0T7H
More data for this
Ligand-Target Pair