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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50126275   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50126275
PNG
(CHEMBL280793 | Isoquinolin-6-yl-(5-phenyl-oxazol-2...)
Show SMILES N(c1ncc(o1)-c1ccccc1)c1ccc2cnccc2c1
Show InChI InChI=1S/C18H13N3O/c1-2-4-13(5-3-1)17-12-20-18(22-17)21-16-7-6-15-11-19-9-8-14(15)10-16/h1-12H,(H,20,21)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 5n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)


Bioorg Med Chem Lett 13: 1345-8 (2003)


Article DOI: 10.1016/s0960-894x(03)00107-0
BindingDB Entry DOI: 10.7270/Q2CV4H3Q
More data for this
Ligand-Target Pair