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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50126288   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50126288
PNG
(1-(5-Chloro-isoquinolin-6-yl)-3-phenyl-urea | CHEM...)
Show SMILES Clc1c(NC(=O)Nc2ccccc2)ccc2cnccc12
Show InChI InChI=1S/C16H12ClN3O/c17-15-13-8-9-18-10-11(13)6-7-14(15)20-16(21)19-12-4-2-1-3-5-12/h1-10H,(H2,19,20,21)
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
n/an/a 1.66E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)


Bioorg Med Chem Lett 13: 1345-8 (2003)


Article DOI: 10.1016/s0960-894x(03)00107-0
BindingDB Entry DOI: 10.7270/Q2CV4H3Q
More data for this
Ligand-Target Pair