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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50129094   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50129094
PNG
(3-Furan-2-yl-N-[4-(4-methyl-oxazol-5-yl)-phenyl]-a...)
Show SMILES Cc1ncoc1-c1ccc(NC(=O)\C=C\c2ccco2)cc1
Show InChI InChI=1S/C17H14N2O3/c1-12-17(22-11-18-12)13-4-6-14(7-5-13)19-16(20)9-8-15-3-2-10-21-15/h2-11H,1H3,(H,19,20)/b9-8+
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
n/an/a>2.00E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of inosine-5'-monophosphate dehydrogenase 2.


Bioorg Med Chem Lett 13: 2059-63 (2003)


Article DOI: 10.1016/s0960-894x(03)00258-0
BindingDB Entry DOI: 10.7270/Q22Z14X1
More data for this
Ligand-Target Pair