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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50129115   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50129115
PNG
(CHEMBL62691 | N-Methyl-N'-[4-(4-methyl-oxazol-5-yl...)
Show SMILES CNc1nc(Nc2ccc(cc2)-c2ocnc2C)nc(n1)-c1ccccc1
Show InChI InChI=1S/C20H18N6O/c1-13-17(27-12-22-13)14-8-10-16(11-9-14)23-20-25-18(24-19(21-2)26-20)15-6-4-3-5-7-15/h3-12H,1-2H3,(H2,21,23,24,25,26)
PDB
MMDB

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Similars

Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of inosine-5'-monophosphate dehydrogenase 2.


Bioorg Med Chem Lett 13: 2059-63 (2003)


Article DOI: 10.1016/s0960-894x(03)00258-0
BindingDB Entry DOI: 10.7270/Q22Z14X1
More data for this
Ligand-Target Pair