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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50129116   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50129116
PNG
(2-Hydroxy-N-{2-[2-(3-methoxy-4-oxazol-5-yl-phenyla...)
Show SMILES COc1cc(Nc2ncc(o2)-c2ccccc2N(C)C(=O)CO)ccc1-c1cnco1
Show InChI InChI=1S/C22H20N4O5/c1-26(21(28)12-27)17-6-4-3-5-15(17)20-11-24-22(31-20)25-14-7-8-16(18(9-14)29-2)19-10-23-13-30-19/h3-11,13,27H,12H2,1-2H3,(H,24,25)
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MMDB

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Article
PubMed
n/an/a 21n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of inosine-5'-monophosphate dehydrogenase 2.


Bioorg Med Chem Lett 13: 2059-63 (2003)


Article DOI: 10.1016/s0960-894x(03)00258-0
BindingDB Entry DOI: 10.7270/Q22Z14X1
More data for this
Ligand-Target Pair