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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50129123   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50129123
PNG
(CHEMBL63466 | [3-Methoxy-4-(2-methyl-oxazol-5-yl)-...)
Show SMILES COc1cc(Nc2ncc(o2)-c2ccccc2)ccc1-c1cnc(C)o1
Show InChI InChI=1S/C20H17N3O3/c1-13-21-12-19(25-13)16-9-8-15(10-17(16)24-2)23-20-22-11-18(26-20)14-6-4-3-5-7-14/h3-12H,1-2H3,(H,22,23)
PDB
MMDB

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Similars

Article
PubMed
n/an/a>2.00E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of inosine-5'-monophosphate dehydrogenase 2.


Bioorg Med Chem Lett 13: 2059-63 (2003)


Article DOI: 10.1016/s0960-894x(03)00258-0
BindingDB Entry DOI: 10.7270/Q22Z14X1
More data for this
Ligand-Target Pair