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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50133735   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50133735
PNG
(1-Methyl-6-(5-o-tolyl-oxazol-2-ylamino)-1H-indole-...)
Show SMILES Cc1ccccc1-c1cnc(Nc2ccc3c(cn(C)c3c2)C#N)o1
Show InChI InChI=1S/C20H16N4O/c1-13-5-3-4-6-16(13)19-11-22-20(25-19)23-15-7-8-17-14(10-21)12-24(2)18(17)9-15/h3-9,11-12H,1-2H3,(H,22,23)
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MMDB

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Article
PubMed
n/an/a 440n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibitory activity tested against inosine-5'-monophosphate dehydrogenase 2 (IMPDH-II) enzyme


Bioorg Med Chem Lett 13: 3557-60 (2003)


Article DOI: 10.1016/s0960-894x(03)00757-1
BindingDB Entry DOI: 10.7270/Q2J67G94
More data for this
Ligand-Target Pair