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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50174780   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50174780
PNG
(7-methoxy-2,2-dimethyl-6-(oxazol-5-yl)-3-(2-(pyrid...)
Show SMILES COc1cc2NC(C)(C)N(CCc3ccncc3)C(=O)c2cc1-c1cnco1
Show InChI InChI=1S/C21H22N4O3/c1-21(2)24-17-11-18(27-3)16(19-12-23-13-28-19)10-15(17)20(26)25(21)9-6-14-4-7-22-8-5-14/h4-5,7-8,10-13,24H,6,9H2,1-3H3
PDB
MMDB

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Article
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UCB Pharma SA

Curated by ChEMBL


Assay Description
Inhibitory activity against IMPDH II


Bioorg Med Chem Lett 15: 5335-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.108
BindingDB Entry DOI: 10.7270/Q2CZ36P8
More data for this
Ligand-Target Pair