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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50174784   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50174784
PNG
(7'-methoxy-3'-methyl-6'-(1,3-oxazol-5-yl)-1'H-spir...)
Show SMILES COc1cc2NC3(CCCC3)N(C)C(=O)c2cc1-c1cnco1
Show InChI InChI=1S/C17H19N3O3/c1-20-16(21)11-7-12(15-9-18-10-23-15)14(22-2)8-13(11)19-17(20)5-3-4-6-17/h7-10,19H,3-6H2,1-2H3
PDB
MMDB

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Article
PubMed
n/an/a 328n/an/an/an/an/an/a



UCB Pharma SA

Curated by ChEMBL


Assay Description
Inhibitory activity against IMPDH II


Bioorg Med Chem Lett 15: 5335-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.108
BindingDB Entry DOI: 10.7270/Q2CZ36P8
More data for this
Ligand-Target Pair