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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50174797   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50174797
PNG
(7'-methoxy-3'-methyl-6'-(1,3-oxazol-5-yl)-4'-oxo-N...)
Show SMILES COc1cc2NC3(CCN(C3)C(=O)Nc3ccccc3)N(C)C(=O)c2cc1-c1cnco1
Show InChI InChI=1S/C23H23N5O4/c1-27-21(29)16-10-17(20-12-24-14-32-20)19(31-2)11-18(16)26-23(27)8-9-28(13-23)22(30)25-15-6-4-3-5-7-15/h3-7,10-12,14,26H,8-9,13H2,1-2H3,(H,25,30)
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n/an/a 393n/an/an/an/an/an/a



UCB Pharma SA

Curated by ChEMBL


Assay Description
Inhibitory activity against IMPDH II


Bioorg Med Chem Lett 15: 5335-9 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.108
BindingDB Entry DOI: 10.7270/Q2CZ36P8
More data for this
Ligand-Target Pair