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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50182918   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50182918
PNG
(1-(benzyloxy)-3-(3-cyano-1-methyl-1H-indol-6-yl)ur...)
Show SMILES Cn1cc(C#N)c2ccc(NC(=O)NOCc3ccccc3)cc12
Show InChI InChI=1S/C18H16N4O2/c1-22-11-14(10-19)16-8-7-15(9-17(16)22)20-18(23)21-24-12-13-5-3-2-4-6-13/h2-9,11H,12H2,1H3,(H2,20,21,23)
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
n/an/a 1.17E+3n/an/an/an/an/an/a



UCB Pharma SA

Curated by ChEMBL


Assay Description
Inhibition of IMPDH2


Bioorg Med Chem Lett 16: 2539-42 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.090
BindingDB Entry DOI: 10.7270/Q2F76C4P
More data for this
Ligand-Target Pair