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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50182927   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50182927
PNG
(1-methyl-3-(2-methyl-3-(pyridin-4-yl)-1H-indol-6-y...)
Show SMILES CN(C(=O)Nc1ccc2c(c(C)[nH]c2c1)-c1ccncc1)c1ccccc1
Show InChI InChI=1S/C22H20N4O/c1-15-21(16-10-12-23-13-11-16)19-9-8-17(14-20(19)24-15)25-22(27)26(2)18-6-4-3-5-7-18/h3-14,24H,1-2H3,(H,25,27)
PDB
MMDB

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Article
PubMed
n/an/a 128n/an/an/an/an/an/a



UCB Pharma SA

Curated by ChEMBL


Assay Description
Inhibition of IMPDH2


Bioorg Med Chem Lett 16: 2539-42 (2006)


Article DOI: 10.1016/j.bmcl.2006.01.090
BindingDB Entry DOI: 10.7270/Q2F76C4P
More data for this
Ligand-Target Pair