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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50228082   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50228082
PNG
(CHEMBL239105 | N-(2-aminophenyl)-6-(4-hydroxy-6-me...)
Show SMILES COc1c(C)c2COC(=O)c2c(O)c1C\C=C(/C)CCC(=O)Nc1ccccc1N
Show InChI InChI=1S/C23H26N2O5/c1-13(9-11-19(26)25-18-7-5-4-6-17(18)24)8-10-15-21(27)20-16(12-30-23(20)28)14(2)22(15)29-3/h4-8,27H,9-12,24H2,1-3H3,(H,25,26)/b13-8+
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MMDB

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Similars

Article
PubMed
650n/an/an/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Inhibition of human IMPDH 2


J Med Chem 50: 6685-91 (2007)


Article DOI: 10.1021/jm070864w
BindingDB Entry DOI: 10.7270/Q2ZK5GCS
More data for this
Ligand-Target Pair