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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 1 (IMPDH1)' and Monomerid = 50263244   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 1 (IMPDH1)


(Homo sapiens (Human))
BDBM50263244
PNG
(CHEMBL510826 | N-(((2R,3S,4R,5R)-5-(6-amino-2-phen...)
Show SMILES COc1c(C)c2COC(=O)c2c(O)c1CCNS(=O)(=O)CS(=O)(=O)NC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)nc(nc12)-c1ccccc1
Show InChI InChI=1S/C29H33N7O11S2/c1-14-17-11-46-29(40)19(17)21(37)16(24(14)45-2)8-9-32-48(41,42)13-49(43,44)33-10-18-22(38)23(39)28(47-18)36-12-31-20-25(30)34-26(35-27(20)36)15-6-4-3-5-7-15/h3-7,12,18,22-23,28,32-33,37-39H,8-11,13H2,1-2H3,(H2,30,34,35)/t18-,22-,23-,28-/m1/s1
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Similars

Article
PubMed
660n/an/an/an/an/an/an/an/a



University of Minnesota

Curated by ChEMBL


Assay Description
Inhibition of human IMP dehydrogenase 1


Bioorg Med Chem 16: 7462-9 (2008)


Article DOI: 10.1016/j.bmc.2008.06.003
BindingDB Entry DOI: 10.7270/Q25D8RPD
More data for this
Ligand-Target Pair