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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50331100   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50331100
PNG
(CHEMBL237760 | methyl 6-(4-hydroxy-6-methoxy-7-met...)
Show SMILES COC(=O)CC\C(C)=C\Cc1c(O)c2C(=O)OCc2c(C)c1OC
Show InChI InChI=1S/C18H22O6/c1-10(6-8-14(19)22-3)5-7-12-16(20)15-13(9-24-18(15)21)11(2)17(12)23-4/h5,20H,6-9H2,1-4H3/b10-5+
PDB
MMDB

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Similars

Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Hokkaido University

Curated by ChEMBL


Assay Description
Inhibition of human IMPDH2 expressed in Escherichia coli strain BL21(DE3) after 60 mins


Bioorg Med Chem 18: 8106-11 (2010)


Article DOI: 10.1016/j.bmc.2010.09.004
BindingDB Entry DOI: 10.7270/Q2Q52PWJ
More data for this
Ligand-Target Pair