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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)' and Monomerid = 50331101   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2)


(Homo sapiens (Human))
BDBM50331101
PNG
(6-(4,6-dimethoxy-7-methyl-3-oxo-1,3-dihydroisobenz...)
Show SMILES COc1c2C(=O)OCc2c(C)c(OC)c1C\C=C(/C)CCC(O)=O
Show InChI InChI=1S/C18H22O6/c1-10(6-8-14(19)20)5-7-12-16(22-3)11(2)13-9-24-18(21)15(13)17(12)23-4/h5H,6-9H2,1-4H3,(H,19,20)/b10-5+
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MMDB

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Article
PubMed
n/an/a 7.20E+4n/an/an/an/an/an/a



Hokkaido University

Curated by ChEMBL


Assay Description
Inhibition of human IMPDH2 expressed in Escherichia coli strain BL21(DE3) after 60 mins


Bioorg Med Chem 18: 8106-11 (2010)


Article DOI: 10.1016/j.bmc.2010.09.004
BindingDB Entry DOI: 10.7270/Q2Q52PWJ
More data for this
Ligand-Target Pair