BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 25 hits with Last Name = 'alifrangis' and Initial = 'lh'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149871
PNG
((R)-2-((3-(biphenyl-4-yloxy)-3-(4-fluorophenyl)pro...)
Show SMILES CN(CC[C@@H](Oc1ccc(cc1)-c1ccccc1)c1ccc(F)cc1)CC(O)=O
Show InChI InChI=1S/C24H24FNO3/c1-26(17-24(27)28)16-15-23(20-7-11-21(25)12-8-20)29-22-13-9-19(10-14-22)18-5-3-2-4-6-18/h2-14,23H,15-17H2,1H3,(H,27,28)/t23-/m1/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 26n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149875
PNG
(CHEMBL361022 | {(R)-4-[5-Chloro-2-(4-methoxy-pheny...)
Show SMILES COc1ccc(Sc2ccc(Cl)cc2N2CCN(CC(O)=O)[C@H](C)C2)cc1
Show InChI InChI=1S/C20H23ClN2O3S/c1-14-12-23(10-9-22(14)13-20(24)25)18-11-15(21)3-8-19(18)27-17-6-4-16(26-2)5-7-17/h3-8,11,14H,9-10,12-13H2,1-2H3,(H,24,25)/t14-/m1/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 150n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149873
PNG
(CHEMBL182162 | {(2R,5S)-4-[2-(4-Methoxy-phenylsulf...)
Show SMILES COc1ccc(Sc2ccccc2N2C[C@@H](C)N(CC(O)=O)C[C@@H]2C)cc1
Show InChI InChI=1S/C21H26N2O3S/c1-15-13-23(16(2)12-22(15)14-21(24)25)19-6-4-5-7-20(19)27-18-10-8-17(26-3)9-11-18/h4-11,15-16H,12-14H2,1-3H3,(H,24,25)/t15-,16+/m1/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 160n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149865
PNG
(CHEMBL181805 | {4-[5-Chloro-2-(4-methoxy-phenylsul...)
Show SMILES COc1ccc(Sc2ccc(Cl)cc2N2CCN(CC(O)=O)C(C)C2)cc1
Show InChI InChI=1S/C20H23ClN2O3S/c1-14-12-23(10-9-22(14)13-20(24)25)18-11-15(21)3-8-19(18)27-17-6-4-16(26-2)5-7-17/h3-8,11,14H,9-10,12-13H2,1-2H3,(H,24,25)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 290n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149856
PNG
(CHEMBL360052 | {Methyl-[(R)-3-phenyl-3-(4-trifluor...)
Show SMILES CN(CC[C@@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1)CC(O)=O
Show InChI InChI=1S/C19H20F3NO3/c1-23(13-18(24)25)12-11-17(14-5-3-2-4-6-14)26-16-9-7-15(8-10-16)19(20,21)22/h2-10,17H,11-13H2,1H3,(H,24,25)/t17-/m1/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 320n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149866
PNG
(CHEMBL181643 | {4-[2-(4-Chloro-phenylsulfanyl)-phe...)
Show SMILES CC1CN(C(C)CN1CC(O)=O)c1ccccc1Sc1ccc(Cl)cc1
Show InChI InChI=1S/C20H23ClN2O2S/c1-14-12-23(15(2)11-22(14)13-20(24)25)18-5-3-4-6-19(18)26-17-9-7-16(21)8-10-17/h3-10,14-15H,11-13H2,1-2H3,(H,24,25)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 360n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149862
PNG
(CHEMBL182521 | [2,5-Dimethyl-4-(2-p-tolylsulfanyl-...)
Show SMILES CC1CN(C(C)CN1CC(O)=O)c1ccccc1Sc1ccc(C)cc1
Show InChI InChI=1S/C21H26N2O2S/c1-15-8-10-18(11-9-15)26-20-7-5-4-6-19(20)23-13-16(2)22(12-17(23)3)14-21(24)25/h4-11,16-17H,12-14H2,1-3H3,(H,24,25)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 550n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149859
PNG
(CHEMBL182666 | {4-[2-(4-Methoxy-phenylsulfanyl)-ph...)
Show SMILES COc1ccc(Sc2ccccc2N2CC(C)N(CC(O)=O)CC2C)cc1
Show InChI InChI=1S/C21H26N2O3S/c1-15-13-23(16(2)12-22(15)14-21(24)25)19-6-4-5-7-20(19)27-18-10-8-17(26-3)9-11-18/h4-11,15-16H,12-14H2,1-3H3,(H,24,25)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 580n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149872
PNG
(CHEMBL182015 | {4-[2-(Biphenyl-4-ylsulfanyl)-pheny...)
Show SMILES CC1CN(C(C)CN1CC(O)=O)c1ccccc1Sc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C26H28N2O2S/c1-19-17-28(20(2)16-27(19)18-26(29)30)24-10-6-7-11-25(24)31-23-14-12-22(13-15-23)21-8-4-3-5-9-21/h3-15,19-20H,16-18H2,1-2H3,(H,29,30)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149868
PNG
(CHEMBL183030 | {(S)-4-[5-Chloro-2-(4-methoxy-pheny...)
Show SMILES COc1ccc(Sc2ccc(Cl)cc2N2CCN(CC(O)=O)[C@@H](C)C2)cc1
Show InChI InChI=1S/C20H23ClN2O3S/c1-14-12-23(10-9-22(14)13-20(24)25)18-11-15(21)3-8-19(18)27-17-6-4-16(26-2)5-7-17/h3-8,11,14H,9-10,12-13H2,1-2H3,(H,24,25)/t14-/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149853
PNG
(CHEMBL181596 | {4-[2-(4-Methoxy-phenylsulfanyl)-ph...)
Show SMILES COc1ccc(Sc2ccccc2N2CCN(CC(O)=O)C(C)(C)C2)cc1
Show InChI InChI=1S/C21H26N2O3S/c1-21(2)15-22(12-13-23(21)14-20(24)25)18-6-4-5-7-19(18)27-17-10-8-16(26-3)9-11-17/h4-11H,12-15H2,1-3H3,(H,24,25)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.50E+3n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149860
PNG
(CHEMBL360501 | {4-[2-(4-Methoxy-phenylsulfanyl)-5-...)
Show SMILES COc1ccc(Sc2ccc(C)cc2N2CCN(CC(O)=O)C(C)C2)cc1
Show InChI InChI=1S/C21H26N2O3S/c1-15-4-9-20(27-18-7-5-17(26-3)6-8-18)19(12-15)23-11-10-22(14-21(24)25)16(2)13-23/h4-9,12,16H,10-11,13-14H2,1-3H3,(H,24,25)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.60E+3n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149876
PNG
(CHEMBL184785 | {4-[5-Chloro-2-(4-methoxy-phenylsul...)
Show SMILES COc1ccc(Sc2ccc(Cl)cc2N2CC(C)N(CC(O)=O)CC2C)cc1
Show InChI InChI=1S/C21H25ClN2O3S/c1-14-12-24(15(2)11-23(14)13-21(25)26)19-10-16(22)4-9-20(19)28-18-7-5-17(27-3)6-8-18/h4-10,14-15H,11-13H2,1-3H3,(H,25,26)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.70E+3n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149877
PNG
(CHEMBL365268 | {4-[2-(4-Methoxy-phenylsulfanyl)-ph...)
Show SMILES COc1ccc(Sc2ccccc2N2CCN(CC(O)=O)C(C)C2)cc1
Show InChI InChI=1S/C20H24N2O3S/c1-15-13-22(12-11-21(15)14-20(23)24)18-5-3-4-6-19(18)26-17-9-7-16(25-2)8-10-17/h3-10,15H,11-14H2,1-2H3,(H,23,24)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.70E+3n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149861
PNG
(CHEMBL182949 | {4-[2-(4-Fluoro-phenylsulfanyl)-phe...)
Show SMILES CC1CN(C(C)CN1CC(O)=O)c1ccccc1Sc1ccc(F)cc1
Show InChI InChI=1S/C20H23FN2O2S/c1-14-12-23(15(2)11-22(14)13-20(24)25)18-5-3-4-6-19(18)26-17-9-7-16(21)8-10-17/h3-10,14-15H,11-13H2,1-2H3,(H,24,25)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.90E+3n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149874
PNG
(CHEMBL363928 | [2,5-Dimethyl-4-(2-phenylsulfanyl-p...)
Show SMILES CC1CN(C(C)CN1CC(O)=O)c1ccccc1Sc1ccccc1
Show InChI InChI=1S/C20H24N2O2S/c1-15-13-22(16(2)12-21(15)14-20(23)24)18-10-6-7-11-19(18)25-17-8-4-3-5-9-17/h3-11,15-16H,12-14H2,1-2H3,(H,23,24)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.90E+3n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149864
PNG
(CHEMBL181698 | {4-[2-(4-Hydroxy-phenylsulfanyl)-ph...)
Show SMILES CC1CN(C(C)CN1CC(O)=O)c1ccccc1Sc1ccc(O)cc1
Show InChI InChI=1S/C20H24N2O3S/c1-14-12-22(15(2)11-21(14)13-20(24)25)18-5-3-4-6-19(18)26-17-9-7-16(23)8-10-17/h3-10,14-15,23H,11-13H2,1-2H3,(H,24,25)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.60E+3n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149863
PNG
(CHEMBL183508 | {4-[5-Methoxy-2-(4-methoxy-phenylsu...)
Show SMILES COc1ccc(Sc2ccc(OC)cc2N2CCN(CC(O)=O)C(C)C2)cc1
Show InChI InChI=1S/C21H26N2O4S/c1-15-13-23(11-10-22(15)14-21(24)25)19-12-17(27-3)6-9-20(19)28-18-7-4-16(26-2)5-8-18/h4-9,12,15H,10-11,13-14H2,1-3H3,(H,24,25)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.60E+3n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149858
PNG
(CHEMBL184996 | {4-[2-(4-Methoxy-phenylsulfanyl)-ph...)
Show SMILES COc1ccc(Sc2ccccc2N2CCN(CC(O)=O)CC2)cc1
Show InChI InChI=1S/C19H22N2O3S/c1-24-15-6-8-16(9-7-15)25-18-5-3-2-4-17(18)21-12-10-20(11-13-21)14-19(22)23/h2-9H,10-14H2,1H3,(H,22,23)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149854
PNG
(CHEMBL180202 | {4-[2-(4-Methoxy-phenylsulfanyl)-ph...)
Show SMILES COc1ccc(Sc2ccccc2N2CCN(CC(O)=O)CC2C)cc1
Show InChI InChI=1S/C20H24N2O3S/c1-15-13-21(14-20(23)24)11-12-22(15)18-5-3-4-6-19(18)26-17-9-7-16(25-2)8-10-17/h3-10,15H,11-14H2,1-2H3,(H,23,24)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149870
PNG
(CHEMBL360768 | {(2R,5R)-4-[2-(4-Methoxy-phenylsulf...)
Show SMILES COc1ccc(Sc2ccccc2N2C[C@@H](C)N(CC(O)=O)C[C@H]2C)cc1
Show InChI InChI=1S/C21H26N2O3S/c1-15-13-23(16(2)12-22(15)14-21(24)25)19-6-4-5-7-20(19)27-18-10-8-17(26-3)9-11-18/h4-11,15-16H,12-14H2,1-3H3,(H,24,25)/t15-,16-/m1/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.60E+4n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149869
PNG
(CHEMBL182917 | {(2S,5S)-4-[2-(4-Methoxy-phenylsulf...)
Show SMILES COc1ccc(Sc2ccccc2N2C[C@H](C)N(CC(O)=O)C[C@@H]2C)cc1
Show InChI InChI=1S/C21H26N2O3S/c1-15-13-23(16(2)12-22(15)14-21(24)25)19-6-4-5-7-20(19)27-18-10-8-17(26-3)9-11-18/h4-11,15-16H,12-14H2,1-3H3,(H,24,25)/t15-,16-/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.80E+4n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149857
PNG
(CHEMBL181745 | {4-[2-(4-Acetylamino-phenylsulfanyl...)
Show SMILES CC1CN(C(C)CN1CC(O)=O)c1ccccc1Sc1ccc(NC(C)=O)cc1
Show InChI InChI=1S/C22H27N3O3S/c1-15-13-25(16(2)12-24(15)14-22(27)28)20-6-4-5-7-21(20)29-19-10-8-18(9-11-19)23-17(3)26/h4-11,15-16H,12-14H2,1-3H3,(H,23,26)(H,27,28)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.20E+4n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149867
PNG
(CHEMBL182618 | {4-[5-Methoxy-2-(4-methoxy-phenylsu...)
Show SMILES COc1ccc(Sc2ccc(OC)cc2N2CC(C)N(CC(O)=O)CC2C)cc1
Show InChI InChI=1S/C22H28N2O4S/c1-15-13-24(16(2)12-23(15)14-22(25)26)20-11-18(28-4)7-10-21(20)29-19-8-5-17(27-3)6-9-19/h5-11,15-16H,12-14H2,1-4H3,(H,25,26)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair
Glycine transporter 1


(Homo sapiens (Human))
BDBM50149855
PNG
(CHEMBL182916 | {(2S,5R)-4-[2-(4-Methoxy-phenylsulf...)
Show SMILES COc1ccc(Sc2ccccc2N2C[C@H](C)N(CC(O)=O)C[C@H]2C)cc1
Show InChI InChI=1S/C21H26N2O3S/c1-15-13-23(16(2)12-22(15)14-21(24)25)19-6-4-5-7-20(19)27-18-10-8-17(26-3)9-11-18/h4-11,15-16H,12-14H2,1-3H3,(H,24,25)/t15-,16+/m0/s1
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.30E+4n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-glycine into cells transfected with human GlyT-1b transporter


Bioorg Med Chem Lett 14: 4027-30 (2004)

Checked by Author
Article DOI: 10.1016/j.bmcl.2004.05.043
BindingDB Entry DOI: 10.7270/Q2DV1JBF
More data for this
Ligand-Target Pair