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Compile Data Set for Download or QSAR

Found 586 hits with Last Name = 'jeppesen' and Initial = 'l'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM85817
PNG
(NNC 11-1585)
Show SMILES C(Oc1nsnc1C1CN2CCC1CC2)C#Cc1ccc(cc1)C#CCOc1nsnc1C1CN2CCC1CC2
Show InChI InChI=1S/C30H32N6O2S2/c1(17-37-29-27(31-39-33-29)25-19-35-13-9-23(25)10-14-35)3-21-5-7-22(8-6-21)4-2-18-38-30-28(32-40-34-30)26-20-36-15-11-24(26)12-16-36/h5-8,23-26H,9-20H2
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0.0790n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by PDSP Ki Database




J Pharmacol Exp Ther 298: 1260-8 (2001)


BindingDB Entry DOI: 10.7270/Q26M35D8
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM85817
PNG
(NNC 11-1585)
Show SMILES C(Oc1nsnc1C1CN2CCC1CC2)C#Cc1ccc(cc1)C#CCOc1nsnc1C1CN2CCC1CC2
Show InChI InChI=1S/C30H32N6O2S2/c1(17-37-29-27(31-39-33-29)25-19-35-13-9-23(25)10-14-35)3-21-5-7-22(8-6-21)4-2-18-38-30-28(32-40-34-30)26-20-36-15-11-24(26)12-16-36/h5-8,23-26H,9-20H2
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0.129n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by PDSP Ki Database




J Pharmacol Exp Ther 298: 1260-8 (2001)


BindingDB Entry DOI: 10.7270/Q26M35D8
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM85816
PNG
(NNC 11-1607)
Show SMILES C(Oc1nsnc1C1CN2CCC1CC2)C#Cc1cccc(c1)C#CCOc1nsnc1C1CN2CCC1CC2
Show InChI InChI=1S/C30H32N6O2S2/c1-4-21(6-2-16-37-29-27(31-39-33-29)25-19-35-12-8-23(25)9-13-35)18-22(5-1)7-3-17-38-30-28(32-40-34-30)26-20-36-14-10-24(26)11-15-36/h1,4-5,18,23-26H,8-17,19-20H2
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2.40n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by PDSP Ki Database




J Pharmacol Exp Ther 298: 1260-8 (2001)


BindingDB Entry DOI: 10.7270/Q26M35D8
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M4


(Homo sapiens (Human))
BDBM85817
PNG
(NNC 11-1585)
Show SMILES C(Oc1nsnc1C1CN2CCC1CC2)C#Cc1ccc(cc1)C#CCOc1nsnc1C1CN2CCC1CC2
Show InChI InChI=1S/C30H32N6O2S2/c1(17-37-29-27(31-39-33-29)25-19-35-13-9-23(25)10-14-35)3-21-5-7-22(8-6-21)4-2-18-38-30-28(32-40-34-30)26-20-36-15-11-24(26)12-16-36/h5-8,23-26H,9-20H2
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2.57n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by PDSP Ki Database




J Pharmacol Exp Ther 298: 1260-8 (2001)


BindingDB Entry DOI: 10.7270/Q26M35D8
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM85817
PNG
(NNC 11-1585)
Show SMILES C(Oc1nsnc1C1CN2CCC1CC2)C#Cc1ccc(cc1)C#CCOc1nsnc1C1CN2CCC1CC2
Show InChI InChI=1S/C30H32N6O2S2/c1(17-37-29-27(31-39-33-29)25-19-35-13-9-23(25)10-14-35)3-21-5-7-22(8-6-21)4-2-18-38-30-28(32-40-34-30)26-20-36-15-11-24(26)12-16-36/h5-8,23-26H,9-20H2
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4.68n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by PDSP Ki Database




J Pharmacol Exp Ther 298: 1260-8 (2001)


BindingDB Entry DOI: 10.7270/Q26M35D8
More data for this
Ligand-Target Pair
CHRM5


(Homo sapiens (Human))
BDBM85817
PNG
(NNC 11-1585)
Show SMILES C(Oc1nsnc1C1CN2CCC1CC2)C#Cc1ccc(cc1)C#CCOc1nsnc1C1CN2CCC1CC2
Show InChI InChI=1S/C30H32N6O2S2/c1(17-37-29-27(31-39-33-29)25-19-35-13-9-23(25)10-14-35)3-21-5-7-22(8-6-21)4-2-18-38-30-28(32-40-34-30)26-20-36-15-11-24(26)12-16-36/h5-8,23-26H,9-20H2
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5.25n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by PDSP Ki Database




J Pharmacol Exp Ther 298: 1260-8 (2001)


BindingDB Entry DOI: 10.7270/Q26M35D8
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM85816
PNG
(NNC 11-1607)
Show SMILES C(Oc1nsnc1C1CN2CCC1CC2)C#Cc1cccc(c1)C#CCOc1nsnc1C1CN2CCC1CC2
Show InChI InChI=1S/C30H32N6O2S2/c1-4-21(6-2-16-37-29-27(31-39-33-29)25-19-35-12-8-23(25)9-13-35)18-22(5-1)7-3-17-38-30-28(32-40-34-30)26-20-36-14-10-24(26)11-15-36/h1,4-5,18,23-26H,8-17,19-20H2
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5.75n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by PDSP Ki Database




J Pharmacol Exp Ther 298: 1260-8 (2001)


BindingDB Entry DOI: 10.7270/Q26M35D8
More data for this
Ligand-Target Pair
CHRM5


(Homo sapiens (Human))
BDBM85816
PNG
(NNC 11-1607)
Show SMILES C(Oc1nsnc1C1CN2CCC1CC2)C#Cc1cccc(c1)C#CCOc1nsnc1C1CN2CCC1CC2
Show InChI InChI=1S/C30H32N6O2S2/c1-4-21(6-2-16-37-29-27(31-39-33-29)25-19-35-12-8-23(25)9-13-35)18-22(5-1)7-3-17-38-30-28(32-40-34-30)26-20-36-14-10-24(26)11-15-36/h1,4-5,18,23-26H,8-17,19-20H2
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6.03n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by PDSP Ki Database




J Pharmacol Exp Ther 298: 1260-8 (2001)


BindingDB Entry DOI: 10.7270/Q26M35D8
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM85816
PNG
(NNC 11-1607)
Show SMILES C(Oc1nsnc1C1CN2CCC1CC2)C#Cc1cccc(c1)C#CCOc1nsnc1C1CN2CCC1CC2
Show InChI InChI=1S/C30H32N6O2S2/c1-4-21(6-2-16-37-29-27(31-39-33-29)25-19-35-12-8-23(25)9-13-35)18-22(5-1)7-3-17-38-30-28(32-40-34-30)26-20-36-14-10-24(26)11-15-36/h1,4-5,18,23-26H,8-17,19-20H2
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8.13n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by PDSP Ki Database




J Pharmacol Exp Ther 298: 1260-8 (2001)


BindingDB Entry DOI: 10.7270/Q26M35D8
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M4


(Homo sapiens (Human))
BDBM85816
PNG
(NNC 11-1607)
Show SMILES C(Oc1nsnc1C1CN2CCC1CC2)C#Cc1cccc(c1)C#CCOc1nsnc1C1CN2CCC1CC2
Show InChI InChI=1S/C30H32N6O2S2/c1-4-21(6-2-16-37-29-27(31-39-33-29)25-19-35-12-8-23(25)9-13-35)18-22(5-1)7-3-17-38-30-28(32-40-34-30)26-20-36-14-10-24(26)11-15-36/h1,4-5,18,23-26H,8-17,19-20H2
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8.13n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by PDSP Ki Database




J Pharmacol Exp Ther 298: 1260-8 (2001)


BindingDB Entry DOI: 10.7270/Q26M35D8
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(RAT)
BDBM85816
PNG
(NNC 11-1607)
Show SMILES C(Oc1nsnc1C1CN2CCC1CC2)C#Cc1cccc(c1)C#CCOc1nsnc1C1CN2CCC1CC2
Show InChI InChI=1S/C30H32N6O2S2/c1-4-21(6-2-16-37-29-27(31-39-33-29)25-19-35-12-8-23(25)9-13-35)18-22(5-1)7-3-17-38-30-28(32-40-34-30)26-20-36-14-10-24(26)11-15-36/h1,4-5,18,23-26H,8-17,19-20H2
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9.55n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by PDSP Ki Database




J Pharmacol Exp Ther 298: 1260-8 (2001)


BindingDB Entry DOI: 10.7270/Q26M35D8
More data for this
Ligand-Target Pair
CHRM5


(Homo sapiens (Human))
BDBM50072228
PNG
(3-[4-(3-Phenyl-prop-2-ynyloxy)-[1,2,5]thiadiazol-3...)
Show SMILES C(Oc1nsnc1C1CN2CCC1CC2)C#Cc1ccccc1
Show InChI InChI=1S/C18H19N3OS/c1-2-5-14(6-3-1)7-4-12-22-18-17(19-23-20-18)16-13-21-10-8-15(16)9-11-21/h1-3,5-6,15-16H,8-13H2
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14.8n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by PDSP Ki Database




J Pharmacol Exp Ther 298: 1260-8 (2001)


BindingDB Entry DOI: 10.7270/Q26M35D8
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50072228
PNG
(3-[4-(3-Phenyl-prop-2-ynyloxy)-[1,2,5]thiadiazol-3...)
Show SMILES C(Oc1nsnc1C1CN2CCC1CC2)C#Cc1ccccc1
Show InChI InChI=1S/C18H19N3OS/c1-2-5-14(6-3-1)7-4-12-22-18-17(19-23-20-18)16-13-21-10-8-15(16)9-11-21/h1-3,5-6,15-16H,8-13H2
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41.7n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by PDSP Ki Database




J Pharmacol Exp Ther 298: 1260-8 (2001)


BindingDB Entry DOI: 10.7270/Q26M35D8
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M4


(Homo sapiens (Human))
BDBM50072228
PNG
(3-[4-(3-Phenyl-prop-2-ynyloxy)-[1,2,5]thiadiazol-3...)
Show SMILES C(Oc1nsnc1C1CN2CCC1CC2)C#Cc1ccccc1
Show InChI InChI=1S/C18H19N3OS/c1-2-5-14(6-3-1)7-4-12-22-18-17(19-23-20-18)16-13-21-10-8-15(16)9-11-21/h1-3,5-6,15-16H,8-13H2
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49n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by PDSP Ki Database




J Pharmacol Exp Ther 298: 1260-8 (2001)


BindingDB Entry DOI: 10.7270/Q26M35D8
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50072228
PNG
(3-[4-(3-Phenyl-prop-2-ynyloxy)-[1,2,5]thiadiazol-3...)
Show SMILES C(Oc1nsnc1C1CN2CCC1CC2)C#Cc1ccccc1
Show InChI InChI=1S/C18H19N3OS/c1-2-5-14(6-3-1)7-4-12-22-18-17(19-23-20-18)16-13-21-10-8-15(16)9-11-21/h1-3,5-6,15-16H,8-13H2
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58.9n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by PDSP Ki Database




J Pharmacol Exp Ther 298: 1260-8 (2001)


BindingDB Entry DOI: 10.7270/Q26M35D8
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M3


(Homo sapiens (Human))
BDBM50072228
PNG
(3-[4-(3-Phenyl-prop-2-ynyloxy)-[1,2,5]thiadiazol-3...)
Show SMILES C(Oc1nsnc1C1CN2CCC1CC2)C#Cc1ccccc1
Show InChI InChI=1S/C18H19N3OS/c1-2-5-14(6-3-1)7-4-12-22-18-17(19-23-20-18)16-13-21-10-8-15(16)9-11-21/h1-3,5-6,15-16H,8-13H2
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77.6n/an/an/an/an/an/an/an/a



University of Melbourne

Curated by PDSP Ki Database




J Pharmacol Exp Ther 298: 1260-8 (2001)


BindingDB Entry DOI: 10.7270/Q26M35D8
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118750
PNG
(2-(Oxalyl-amino)-6-phenethyl-4,5,6,7-tetrahydro-th...)
Show SMILES OC(=O)C(=O)Nc1sc2CN(CCc3ccccc3)CCc2c1C(O)=O
Show InChI InChI=1S/C18H18N2O5S/c21-15(18(24)25)19-16-14(17(22)23)12-7-9-20(10-13(12)26-16)8-6-11-4-2-1-3-5-11/h1-5H,6-10H2,(H,19,21)(H,22,23)(H,24,25)
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270n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118792
PNG
(2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]P...)
Show SMILES OC(=O)C(=O)Nc1sc2CNCCc2c1C(O)=O
Show InChI InChI=1S/C10H10N2O5S/c13-7(10(16)17)12-8-6(9(14)15)4-1-2-11-3-5(4)18-8/h11H,1-3H2,(H,12,13)(H,14,15)(H,16,17)
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290n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118786
PNG
(6-(3-Methoxy-benzyl)-2-(oxalyl-amino)-4,5,6,7-tetr...)
Show SMILES COc1cccc(CN2CCc3c(C2)sc(NC(=O)C(O)=O)c3C(O)=O)c1
Show InChI InChI=1S/C18H18N2O6S/c1-26-11-4-2-3-10(7-11)8-20-6-5-12-13(9-20)27-16(14(12)17(22)23)19-15(21)18(24)25/h2-4,7H,5-6,8-9H2,1H3,(H,19,21)(H,22,23)(H,24,25)
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700n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118794
PNG
(2-(Oxalyl-amino)-6-pyridin-3-ylmethyl-4,5,6,7-tetr...)
Show SMILES OC(=O)C(=O)Nc1sc2CN(Cc3cccnc3)CCc2c1C(O)=O
Show InChI InChI=1S/C16H15N3O5S/c20-13(16(23)24)18-14-12(15(21)22)10-3-5-19(8-11(10)25-14)7-9-2-1-4-17-6-9/h1-2,4,6H,3,5,7-8H2,(H,18,20)(H,21,22)(H,23,24)
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900n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118793
PNG
(6-Methyl-2-(oxalyl-amino)-4,5,6,7-tetrahydro-thien...)
Show SMILES CN1CCc2c(C1)sc(NC(=O)C(O)=O)c2C(O)=O
Show InChI InChI=1S/C11H12N2O5S/c1-13-3-2-5-6(4-13)19-9(7(5)10(15)16)12-8(14)11(17)18/h2-4H2,1H3,(H,12,14)(H,15,16)(H,17,18)
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1.00E+3n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118774
PNG
(6-Benzyl-2-(oxalyl-amino)-4,5,6,7-tetrahydro-thien...)
Show SMILES OC(=O)C(=O)Nc1sc2CN(Cc3ccccc3)CCc2c1C(O)=O
Show InChI InChI=1S/C17H16N2O5S/c20-14(17(23)24)18-15-13(16(21)22)11-6-7-19(9-12(11)25-15)8-10-4-2-1-3-5-10/h1-5H,6-9H2,(H,18,20)(H,21,22)(H,23,24)
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1.00E+3n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118742
PNG
(2-(Oxalyl-amino)-6-pyridin-2-ylmethyl-4,5,6,7-tetr...)
Show SMILES OC(=O)C(=O)Nc1sc2CN(Cc3ccccn3)CCc2c1C(O)=O
Show InChI InChI=1S/C16H15N3O5S/c20-13(16(23)24)18-14-12(15(21)22)10-4-6-19(8-11(10)25-14)7-9-3-1-2-5-17-9/h1-3,5H,4,6-8H2,(H,18,20)(H,21,22)(H,23,24)
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1.00E+3n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118755
PNG
(2-(Oxalyl-amino)-6-pyridin-4-ylmethyl-4,5,6,7-tetr...)
Show SMILES OC(=O)C(=O)Nc1sc2CN(Cc3ccncc3)CCc2c1C(O)=O
Show InChI InChI=1S/C16H15N3O5S/c20-13(16(23)24)18-14-12(15(21)22)10-3-6-19(8-11(10)25-14)7-9-1-4-17-5-2-9/h1-2,4-5H,3,6-8H2,(H,18,20)(H,21,22)(H,23,24)
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1.10E+3n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118772
PNG
(2-(Oxalyl-amino)-6-oxo-4,5,6,7-tetrahydro-benzo[b]...)
Show SMILES OC(=O)C(=O)Nc1sc2CC(=O)CCc2c1C(O)=O
Show InChI InChI=1S/C11H9NO6S/c13-4-1-2-5-6(3-4)19-9(7(5)10(15)16)12-8(14)11(17)18/h1-3H2,(H,12,14)(H,15,16)(H,17,18)
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1.30E+3n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118767
PNG
(2-(Oxalyl-amino)-6-quinolin-2-ylmethyl-4,5,6,7-tet...)
Show SMILES OC(=O)C(=O)Nc1sc2CN(Cc3ccc4ccccc4n3)CCc2c1C(O)=O
Show InChI InChI=1S/C20H17N3O5S/c24-17(20(27)28)22-18-16(19(25)26)13-7-8-23(10-15(13)29-18)9-12-6-5-11-3-1-2-4-14(11)21-12/h1-6H,7-10H2,(H,22,24)(H,25,26)(H,27,28)
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1.80E+3n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118771
PNG
(2-(carboxyformamido)-6-hydroxy-4,5,6,7-tetrahydrob...)
Show SMILES OC1CCc2c(C1)sc(NC(=O)C(O)=O)c2C(O)=O
Show InChI InChI=1S/C11H11NO6S/c13-4-1-2-5-6(3-4)19-9(7(5)10(15)16)12-8(14)11(17)18/h4,13H,1-3H2,(H,12,14)(H,15,16)(H,17,18)
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2.00E+3n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118741
PNG
(6-[1,3]Dioxolan-2-yl-2-(oxalyl-amino)-4,5,6,7-tetr...)
Show SMILES OC(=O)C(=O)Nc1sc2CC(CCc2c1C(O)=O)C1OCCO1
Show InChI InChI=1S/C14H15NO7S/c16-10(13(19)20)15-11-9(12(17)18)7-2-1-6(5-8(7)23-11)14-21-3-4-22-14/h6,14H,1-5H2,(H,15,16)(H,17,18)(H,19,20)
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2.20E+3n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118765
PNG
(3-(carboxyformamido)-5-(4-(carboxymethoxy)phenyl)t...)
Show SMILES OC(=O)COc1ccc(cc1)-c1cc(NC(=O)C(O)=O)c(s1)C(O)=O
Show InChI InChI=1S/C15H11NO8S/c17-11(18)6-24-8-3-1-7(2-4-8)10-5-9(12(25-10)14(20)21)16-13(19)15(22)23/h1-5H,6H2,(H,16,19)(H,17,18)(H,20,21)(H,22,23)
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2.50E+3n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118750
PNG
(2-(Oxalyl-amino)-6-phenethyl-4,5,6,7-tetrahydro-th...)
Show SMILES OC(=O)C(=O)Nc1sc2CN(CCc3ccccc3)CCc2c1C(O)=O
Show InChI InChI=1S/C18H18N2O5S/c21-15(18(24)25)19-16-14(17(22)23)12-7-9-20(10-13(12)26-16)8-6-11-4-2-1-3-5-11/h1-5H,6-10H2,(H,19,21)(H,22,23)(H,24,25)
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3.20E+3n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibition of human recombinant Protein-tyrosine phosphatase 1B.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118782
PNG
(3-(carboxyformamido)-5-(4-hydroxyphenyl)thiophene-...)
Show SMILES OC(=O)C(=O)Nc1cc(sc1C(O)=O)-c1ccc(O)cc1
Show InChI InChI=1S/C13H9NO6S/c15-7-3-1-6(2-4-7)9-5-8(10(21-9)12(17)18)14-11(16)13(19)20/h1-5,15H,(H,14,16)(H,17,18)(H,19,20)
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4.50E+3n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118780
PNG
(3-(carboxyformamido)-5-(3-nitrophenyl)thiophene-2-...)
Show SMILES OC(=O)C(=O)Nc1cc(sc1C(O)=O)-c1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C13H8N2O7S/c16-11(13(19)20)14-8-5-9(23-10(8)12(17)18)6-2-1-3-7(4-6)15(21)22/h1-5H,(H,14,16)(H,17,18)(H,19,20)
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4.70E+3n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118792
PNG
(2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]P...)
Show SMILES OC(=O)C(=O)Nc1sc2CNCCc2c1C(O)=O
Show InChI InChI=1S/C10H10N2O5S/c13-7(10(16)17)12-8-6(9(14)15)4-1-2-11-3-5(4)18-8/h11H,1-3H2,(H,12,13)(H,14,15)(H,16,17)
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4.70E+3n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibition of human recombinant Protein-tyrosine phosphatase 1B.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118783
PNG
(2-(Oxalyl-amino)-6-oxo-4,5,6,7-tetrahydro-6lambda*...)
Show SMILES OC(=O)C(=O)Nc1sc2CS(=O)CCc2c1C(O)=O
Show InChI InChI=1S/C10H9NO6S2/c12-7(10(15)16)11-8-6(9(13)14)4-1-2-19(17)3-5(4)18-8/h1-3H2,(H,11,12)(H,13,14)(H,15,16)
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5.10E+3n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase alpha


(Homo sapiens (Human))
BDBM50118752
PNG
(6-(3,3-Diphenyl-propyl)-2-(oxalyl-amino)-4,5,6,7-t...)
Show SMILES OC(=O)C(=O)Nc1sc2CN(CCC(c3ccccc3)c3ccccc3)CCc2c1C(O)=O
Show InChI InChI=1S/C25H24N2O5S/c28-22(25(31)32)26-23-21(24(29)30)19-12-14-27(15-20(19)33-23)13-11-18(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-10,18H,11-15H2,(H,26,28)(H,29,30)(H,31,32)
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5.80E+3n/an/an/an/an/an/a7.0n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against T cell protein tyrosine phosphatase (TC-PTP) using p-nitrophenyl phosphate as substrate at pH 7.0


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118752
PNG
(6-(3,3-Diphenyl-propyl)-2-(oxalyl-amino)-4,5,6,7-t...)
Show SMILES OC(=O)C(=O)Nc1sc2CN(CCC(c3ccccc3)c3ccccc3)CCc2c1C(O)=O
Show InChI InChI=1S/C25H24N2O5S/c28-22(25(31)32)26-23-21(24(29)30)19-12-14-27(15-20(19)33-23)13-11-18(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-10,18H,11-15H2,(H,26,28)(H,29,30)(H,31,32)
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5.90E+3n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibition of human recombinant Protein-tyrosine phosphatase 1B.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118758
PNG
(5-(3-Amino-phenyl)-3-(oxalyl-amino)-thiophene-2-ca...)
Show SMILES Nc1cccc(c1)-c1cc(NC(=O)C(O)=O)c(s1)C(O)=O
Show InChI InChI=1S/C13H10N2O5S/c14-7-3-1-2-6(4-7)9-5-8(10(21-9)12(17)18)15-11(16)13(19)20/h1-5H,14H2,(H,15,16)(H,17,18)(H,19,20)
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6.10E+3n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118763
PNG
(2-(Oxalyl-amino)-6,6-dioxo-4,5,6,7-tetrahydro-6lam...)
Show SMILES OC(=O)C(=O)Nc1sc2CS(=O)(=O)CCc2c1C(O)=O
Show InChI InChI=1S/C10H9NO7S2/c12-7(10(15)16)11-8-6(9(13)14)4-1-2-20(17,18)3-5(4)19-8/h1-3H2,(H,11,12)(H,13,14)(H,15,16)
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6.10E+3n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118750
PNG
(2-(Oxalyl-amino)-6-phenethyl-4,5,6,7-tetrahydro-th...)
Show SMILES OC(=O)C(=O)Nc1sc2CN(CCc3ccccc3)CCc2c1C(O)=O
Show InChI InChI=1S/C18H18N2O5S/c21-15(18(24)25)19-16-14(17(22)23)12-7-9-20(10-13(12)26-16)8-6-11-4-2-1-3-5-11/h1-5H,6-10H2,(H,19,21)(H,22,23)(H,24,25)
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7.20E+3n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibition of human recombinant Protein-tyrosine phosphatase 1B.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118790
PNG
(2-(Oxalyl-amino)-6-(3-phenyl-propyl)-4,5,6,7-tetra...)
Show SMILES OC(=O)C(=O)Nc1sc2CN(CCCc3ccccc3)CCc2c1C(O)=O
Show InChI InChI=1S/C19H20N2O5S/c22-16(19(25)26)20-17-15(18(23)24)13-8-10-21(11-14(13)27-17)9-4-7-12-5-2-1-3-6-12/h1-3,5-6H,4,7-11H2,(H,20,22)(H,23,24)(H,25,26)
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7.30E+3n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibition of human recombinant Protein-tyrosine phosphatase 1B.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118754
PNG
(6-(2-Biphenyl-4-yl-ethyl)-2-(oxalyl-amino)-4,5,6,7...)
Show SMILES OC(=O)C(=O)Nc1sc2CN(CCc3ccc(cc3)-c3ccccc3)CCc2c1C(O)=O
Show InChI InChI=1S/C24H22N2O5S/c27-21(24(30)31)25-22-20(23(28)29)18-11-13-26(14-19(18)32-22)12-10-15-6-8-17(9-7-15)16-4-2-1-3-5-16/h1-9H,10-14H2,(H,25,27)(H,28,29)(H,30,31)
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8.00E+3n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibition of human recombinant Protein-tyrosine phosphatase 1B.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118756
PNG
(3-(carboxyformamido)-5-(3,5-dimethoxyphenyl)thioph...)
Show SMILES COc1cc(OC)cc(c1)-c1cc(NC(=O)C(O)=O)c(s1)C(O)=O
Show InChI InChI=1S/C15H13NO7S/c1-22-8-3-7(4-9(5-8)23-2)11-6-10(12(24-11)14(18)19)16-13(17)15(20)21/h3-6H,1-2H3,(H,16,17)(H,18,19)(H,20,21)
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8.00E+3n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118796
PNG
(6-(OXALYL-AMINO)-1H-INDOLE-5-CARBOXYLIC ACID | 6-(...)
Show SMILES OC(=O)C(=O)Nc1cc2[nH]ccc2cc1C(O)=O
Show InChI InChI=1S/C11H8N2O5/c14-9(11(17)18)13-8-4-7-5(1-2-12-7)3-6(8)10(15)16/h1-4,12H,(H,13,14)(H,15,16)(H,17,18)
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8.00E+3n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118740
PNG
(3-(carboxyformamido)-5-(4-fluorophenyl)thiophene-2...)
Show SMILES OC(=O)C(=O)Nc1cc(sc1C(O)=O)-c1ccc(F)cc1
Show InChI InChI=1S/C13H8FNO5S/c14-7-3-1-6(2-4-7)9-5-8(10(21-9)12(17)18)15-11(16)13(19)20/h1-5H,(H,15,16)(H,17,18)(H,19,20)
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8.00E+3n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118762
PNG
(2-(Oxalyl-amino)-4,5,6,7-tetrahydro-benzo[b]thioph...)
Show SMILES OC(=O)C(=O)Nc1sc2CCCCc2c1C(O)=O
Show InChI InChI=1S/C11H11NO5S/c13-8(11(16)17)12-9-7(10(14)15)5-3-1-2-4-6(5)18-9/h1-4H2,(H,12,13)(H,14,15)(H,16,17)
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8.10E+3n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118787
PNG
(2-(Oxalyl-amino)-4,7-dihydro-5H-thieno[2,3-c]thiop...)
Show SMILES OC(=O)C(=O)Nc1sc2CSCCc2c1C(O)=O
Show InChI InChI=1S/C10H9NO5S2/c12-7(10(15)16)11-8-6(9(13)14)4-1-2-17-3-5(4)18-8/h1-3H2,(H,11,12)(H,13,14)(H,15,16)
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8.30E+3n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118786
PNG
(6-(3-Methoxy-benzyl)-2-(oxalyl-amino)-4,5,6,7-tetr...)
Show SMILES COc1cccc(CN2CCc3c(C2)sc(NC(=O)C(O)=O)c3C(O)=O)c1
Show InChI InChI=1S/C18H18N2O6S/c1-26-11-4-2-3-10(7-11)8-20-6-5-12-13(9-20)27-16(14(12)17(22)23)19-15(21)18(24)25/h2-4,7H,5-6,8-9H2,1H3,(H,19,21)(H,22,23)(H,24,25)
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8.30E+3n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibition of human recombinant Protein-tyrosine phosphatase 1B.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118748
PNG
(2-(Oxalyl-amino)-6-(2-pyridin-4-yl-ethyl)-4,5,6,7-...)
Show SMILES OC(=O)C(=O)Nc1sc2CN(CCc3ccncc3)CCc2c1C(O)=O
Show InChI InChI=1S/C17H17N3O5S/c21-14(17(24)25)19-15-13(16(22)23)11-4-8-20(9-12(11)26-15)7-3-10-1-5-18-6-2-10/h1-2,5-6H,3-4,7-9H2,(H,19,21)(H,22,23)(H,24,25)
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8.70E+3n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibition of human recombinant Protein-tyrosine phosphatase 1B.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118770
PNG
(2-(Oxalyl-amino)-6-(2-thiophen-3-yl-ethyl)-4,5,6,7...)
Show SMILES OC(=O)C(=O)Nc1sc2CN(CCc3ccsc3)CCc2c1C(O)=O
Show InChI InChI=1S/C16H16N2O5S2/c19-13(16(22)23)17-14-12(15(20)21)10-2-5-18(7-11(10)25-14)4-1-9-3-6-24-8-9/h3,6,8H,1-2,4-5,7H2,(H,17,19)(H,20,21)(H,22,23)
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9.00E+3n/an/an/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibition of human recombinant Protein-tyrosine phosphatase 1B.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50118759
PNG
(3-(carboxyformamido)-5-(4-methoxyphenyl)thiophene-...)
Show SMILES COc1ccc(cc1)-c1cc(NC(=O)C(O)=O)c(s1)C(O)=O
Show InChI InChI=1S/C14H11NO6S/c1-21-8-4-2-7(3-5-8)10-6-9(11(22-10)13(17)18)15-12(16)14(19)20/h2-6H,1H3,(H,15,16)(H,17,18)(H,19,20)
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9.00E+3n/an/an/an/an/an/a5.5n/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Inhibitory effect against recombinant human protein-tyrosine phosphatase 1B (PTP1B), using p-nitrophenyl phosphate substrate at pH 5.5.


J Med Chem 45: 4443-59 (2002)


Article DOI: 10.1021/jm0209026
BindingDB Entry DOI: 10.7270/Q2QJ7GM5
More data for this
Ligand-Target Pair
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