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Compile Data Set for Download or QSAR

Found 364 hits with Last Name = 'nanda' and Initial = 'kk'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50234418
PNG
((2,3-Dichloro-phenyl)-[5-methoxy-2-methyl-3-(2-mor...)
Show SMILES COc1ccc2n(C(=O)c3cccc(Cl)c3Cl)c(C)c(CCN3CCOCC3)c2c1
Show InChI InChI=1S/C23H24Cl2N2O3/c1-15-17(8-9-26-10-12-30-13-11-26)19-14-16(29-2)6-7-21(19)27(15)23(28)18-4-3-5-20(24)22(18)25/h3-7,14H,8-13H2,1-2H3
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10n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB2 receptor


Bioorg Med Chem Lett 21: 2354-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.082
BindingDB Entry DOI: 10.7270/Q2C829MB
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)
BDBM50218669
PNG
(CHEMBL97868)
Show SMILES CCN(CC)c1nccn2c(Nc3ccc(Cl)cc3Cl)nc(CC)c12
Show InChI InChI=1S/C18H21Cl2N5/c1-4-14-16-17(24(5-2)6-3)21-9-10-25(16)18(22-14)23-15-8-7-12(19)11-13(15)20/h7-11H,4-6H2,1-3H3,(H,22,23)
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127n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.


Bioorg Med Chem Lett 12: 291-4 (2002)


Article DOI: 10.1016/s0960-894x(01)00741-7
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)
BDBM50218662
PNG
(CHEMBL100943)
Show SMILES CCN(CC)c1nccn2c(Nc3c(C)cc(C)cc3C)nc(CC)c12
Show InChI InChI=1S/C21H29N5/c1-7-17-19-20(25(8-2)9-3)22-10-11-26(19)21(23-17)24-18-15(5)12-14(4)13-16(18)6/h10-13H,7-9H2,1-6H3,(H,23,24)
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143n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.


Bioorg Med Chem Lett 12: 291-4 (2002)


Article DOI: 10.1016/s0960-894x(01)00741-7
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)
BDBM50218754
PNG
(CHEMBL101574)
Show SMILES CCCN(CCC)c1nccn2c(Nc3c(C)cc(C)cc3C)nc(CC)c12
Show InChI InChI=1S/C23H33N5/c1-7-11-27(12-8-2)22-21-19(9-3)25-23(28(21)13-10-24-22)26-20-17(5)14-16(4)15-18(20)6/h10,13-15H,7-9,11-12H2,1-6H3,(H,25,26)
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173n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.


Bioorg Med Chem Lett 12: 291-4 (2002)


Article DOI: 10.1016/s0960-894x(01)00741-7
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)
BDBM50218684
PNG
(CHEMBL99741)
Show SMILES CCCN(CCC)c1nccn2c(Nc3ccc(Cl)cc3Cl)nc(CC)c12
Show InChI InChI=1S/C20H25Cl2N5/c1-4-10-26(11-5-2)19-18-16(6-3)24-20(27(18)12-9-23-19)25-17-8-7-14(21)13-15(17)22/h7-9,12-13H,4-6,10-11H2,1-3H3,(H,24,25)
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223n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.


Bioorg Med Chem Lett 12: 291-4 (2002)


Article DOI: 10.1016/s0960-894x(01)00741-7
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)
BDBM50218683
PNG
(CHEMBL98643)
Show SMILES CCCc1nc(N(C)c2ccc(Cl)cc2Cl)n2ccnc(N(CC)CC)c12
Show InChI InChI=1S/C20H25Cl2N5/c1-5-8-16-18-19(26(6-2)7-3)23-11-12-27(18)20(24-16)25(4)17-10-9-14(21)13-15(17)22/h9-13H,5-8H2,1-4H3
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324n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.


Bioorg Med Chem Lett 12: 291-4 (2002)


Article DOI: 10.1016/s0960-894x(01)00741-7
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)
BDBM50218680
PNG
(CHEMBL318652)
Show SMILES CCN(CC)c1nccn2c(Nc3ccc(Cl)cc3Cl)nc(C)c12
Show InChI InChI=1S/C17H19Cl2N5/c1-4-23(5-2)16-15-11(3)21-17(24(15)9-8-20-16)22-14-7-6-12(18)10-13(14)19/h6-10H,4-5H2,1-3H3,(H,21,22)
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485n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.


Bioorg Med Chem Lett 12: 291-4 (2002)


Article DOI: 10.1016/s0960-894x(01)00741-7
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)
BDBM50218753
PNG
(CHEMBL101093)
Show SMILES CCCN(CCC)c1nccn2c(Nc3ccc(Cl)cc3Cl)nc(CCC)c12
Show InChI InChI=1S/C21H27Cl2N5/c1-4-7-18-19-20(27(11-5-2)12-6-3)24-10-13-28(19)21(26-18)25-17-9-8-15(22)14-16(17)23/h8-10,13-14H,4-7,11-12H2,1-3H3,(H,25,26)
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492n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.


Bioorg Med Chem Lett 12: 291-4 (2002)


Article DOI: 10.1016/s0960-894x(01)00741-7
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)
BDBM50218687
PNG
(CHEMBL327285)
Show SMILES CCCN(CCC)c1nccn2c(Nc3ccc(Cl)cc3Cl)nc(C)c12
Show InChI InChI=1S/C19H23Cl2N5/c1-4-9-25(10-5-2)18-17-13(3)23-19(26(17)11-8-22-18)24-16-7-6-14(20)12-15(16)21/h6-8,11-12H,4-5,9-10H2,1-3H3,(H,23,24)
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597n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.


Bioorg Med Chem Lett 12: 291-4 (2002)


Article DOI: 10.1016/s0960-894x(01)00741-7
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)
BDBM50218685
PNG
(CHEMBL316839)
Show SMILES CCCN(CCC)c1nccn2c(nc(CCC)c12)N(C)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C22H29Cl2N5/c1-5-8-18-20-21(28(12-6-2)13-7-3)25-11-14-29(20)22(26-18)27(4)19-10-9-16(23)15-17(19)24/h9-11,14-15H,5-8,12-13H2,1-4H3
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623n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.


Bioorg Med Chem Lett 12: 291-4 (2002)


Article DOI: 10.1016/s0960-894x(01)00741-7
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)
BDBM50218661
PNG
(CHEMBL98693)
Show SMILES CCCN(CCC)c1nccn2c(nc(C)c12)N(CC)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C21H27Cl2N5/c1-5-11-26(12-6-2)20-19-15(4)25-21(28(19)13-10-24-20)27(7-3)18-9-8-16(22)14-17(18)23/h8-10,13-14H,5-7,11-12H2,1-4H3
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671n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.


Bioorg Med Chem Lett 12: 291-4 (2002)


Article DOI: 10.1016/s0960-894x(01)00741-7
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)
BDBM50218681
PNG
(CHEMBL98091)
Show SMILES CCCc1nc(Nc2ccc(Cl)cc2Cl)n2ccnc(N(CC)CC)c12
Show InChI InChI=1S/C19H23Cl2N5/c1-4-7-16-17-18(25(5-2)6-3)22-10-11-26(17)19(24-16)23-15-9-8-13(20)12-14(15)21/h8-12H,4-7H2,1-3H3,(H,23,24)
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825n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.


Bioorg Med Chem Lett 12: 291-4 (2002)


Article DOI: 10.1016/s0960-894x(01)00741-7
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)
BDBM50218679
PNG
(CHEMBL100168)
Show SMILES CCCc1nc(Nc2c(C)cc(C)cc2C)n2ccnc(N(CC)CC)c12
Show InChI InChI=1S/C22H31N5/c1-7-10-18-20-21(26(8-2)9-3)23-11-12-27(20)22(24-18)25-19-16(5)13-15(4)14-17(19)6/h11-14H,7-10H2,1-6H3,(H,24,25)
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1.14E+3n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.


Bioorg Med Chem Lett 12: 291-4 (2002)


Article DOI: 10.1016/s0960-894x(01)00741-7
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)
BDBM50218759
PNG
(CHEMBL99155)
Show SMILES CCCN(CCC)c1nccn2c(nc(C)c12)N(C)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C20H25Cl2N5/c1-5-10-26(11-6-2)19-18-14(3)24-20(27(18)12-9-23-19)25(4)17-8-7-15(21)13-16(17)22/h7-9,12-13H,5-6,10-11H2,1-4H3
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1.36E+3n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.


Bioorg Med Chem Lett 12: 291-4 (2002)


Article DOI: 10.1016/s0960-894x(01)00741-7
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)
BDBM50218975
PNG
(CHEMBL431229)
Show SMILES CCCN(CCC)c1nccn2c(nc(CC)c12)N(CC)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C22H29Cl2N5/c1-5-12-27(13-6-2)21-20-18(7-3)26-22(29(20)14-11-25-21)28(8-4)19-10-9-16(23)15-17(19)24/h9-11,14-15H,5-8,12-13H2,1-4H3
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1.54E+3n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.


Bioorg Med Chem Lett 12: 291-4 (2002)


Article DOI: 10.1016/s0960-894x(01)00741-7
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50234418
PNG
((2,3-Dichloro-phenyl)-[5-methoxy-2-methyl-3-(2-mor...)
Show SMILES COc1ccc2n(C(=O)c3cccc(Cl)c3Cl)c(C)c(CCN3CCOCC3)c2c1
Show InChI InChI=1S/C23H24Cl2N2O3/c1-15-17(8-9-26-10-12-30-13-11-26)19-14-16(29-2)6-7-21(19)27(15)23(28)18-4-3-5-20(24)22(18)25/h3-7,14H,8-13H2,1-2H3
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2.00E+3n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to human CB1 receptor


Bioorg Med Chem Lett 21: 2354-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.082
BindingDB Entry DOI: 10.7270/Q2C829MB
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)
BDBM50218678
PNG
(CHEMBL317436)
Show SMILES CCCc1nc(N(CC)c2ccc(Cl)cc2Cl)n2ccnc(N(CC)CC)c12
Show InChI InChI=1S/C21H27Cl2N5/c1-5-9-17-19-20(26(6-2)7-3)24-12-13-28(19)21(25-17)27(8-4)18-11-10-15(22)14-16(18)23/h10-14H,5-9H2,1-4H3
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2.22E+3n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.


Bioorg Med Chem Lett 12: 291-4 (2002)


Article DOI: 10.1016/s0960-894x(01)00741-7
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)
BDBM50218797
PNG
(CHEMBL320384)
Show SMILES CCCc1nc(N(CC)c2ccc(Cl)cc2Cl)n2ccnc(N(C)C)c12
Show InChI InChI=1S/C19H23Cl2N5/c1-5-7-15-17-18(24(3)4)22-10-11-26(17)19(23-15)25(6-2)16-9-8-13(20)12-14(16)21/h8-12H,5-7H2,1-4H3
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2.42E+3n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.


Bioorg Med Chem Lett 12: 291-4 (2002)


Article DOI: 10.1016/s0960-894x(01)00741-7
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)
BDBM50218686
PNG
(CHEMBL318729)
Show SMILES CCN(c1nc(CC)c2c(nccn12)N(C)C)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C18H21Cl2N5/c1-5-14-16-17(23(3)4)21-9-10-25(16)18(22-14)24(6-2)15-8-7-12(19)11-13(15)20/h7-11H,5-6H2,1-4H3
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2.88E+3n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.


Bioorg Med Chem Lett 12: 291-4 (2002)


Article DOI: 10.1016/s0960-894x(01)00741-7
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)
BDBM50218660
PNG
(CHEMBL99550)
Show SMILES CCC(CC)Nc1nccn2c(Nc3ccc(Cl)cc3Cl)nc(C)c12
Show InChI InChI=1S/C18H21Cl2N5/c1-4-13(5-2)23-17-16-11(3)22-18(25(16)9-8-21-17)24-15-7-6-12(19)10-14(15)20/h6-10,13H,4-5H2,1-3H3,(H,21,23)(H,22,24)
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>3.00E+3n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.


Bioorg Med Chem Lett 12: 291-4 (2002)


Article DOI: 10.1016/s0960-894x(01)00741-7
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50340312
PNG
((2,3-dichlorophenyl)(1-((4,4-difluoropiperidin-1-y...)
Show SMILES FC1(F)CCN(Cc2nc(C(=O)c3cccc(Cl)c3Cl)n3ccccc23)CC1
Show InChI InChI=1S/C20H17Cl2F2N3O/c21-14-5-3-4-13(17(14)22)18(28)19-25-15(16-6-1-2-9-27(16)19)12-26-10-7-20(23,24)8-11-26/h1-6,9H,7-8,10-12H2
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n/an/a 0.300n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP level


Bioorg Med Chem Lett 21: 2354-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.082
BindingDB Entry DOI: 10.7270/Q2C829MB
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50340311
PNG
((3-fluoro-2-(trifluoromethyl)phenyl)(1-(morpholino...)
Show SMILES Fc1cccc(C(=O)c2nc(CN3CCOCC3)c3ccccn23)c1C(F)(F)F
Show InChI InChI=1S/C20H17F4N3O2/c21-14-5-3-4-13(17(14)20(22,23)24)18(28)19-25-15(12-26-8-10-29-11-9-26)16-6-1-2-7-27(16)19/h1-7H,8-12H2
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n/an/a 0.700n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP level


Bioorg Med Chem Lett 21: 2354-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.082
BindingDB Entry DOI: 10.7270/Q2C829MB
More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo sapiens (Human))
BDBM50022671
PNG
(CHEMBL3298265)
Show SMILES Cc1cn2cc(CNc3ncnc4ccc(nc34)N3CCC[C@@H]3c3cc(F)ccc3F)nc2s1
Show InChI InChI=1S/C24H21F2N7S/c1-14-11-32-12-16(30-24(32)34-14)10-27-23-22-19(28-13-29-23)6-7-21(31-22)33-8-2-3-20(33)17-9-15(25)4-5-18(17)26/h4-7,9,11-13,20H,2-3,8,10H2,1H3,(H,27,28,29)/t20-/m1/s1
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n/an/a 1.5n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of purified TrkA cytoplasmic domain (unknown origin) by HTRF assay


J Med Chem 57: 5800-16 (2014)


Article DOI: 10.1021/jm5006429
BindingDB Entry DOI: 10.7270/Q2BV7J69
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50340313
PNG
(1-((4,4-difluoropiperidin-1-yl)methyl)-N-(6-(trifl...)
Show SMILES FC(F)(F)c1cccc(NC(=O)c2nc(CN3CCC(F)(F)CC3)c3ccccn23)n1
Show InChI InChI=1S/C20H18F5N5O/c21-19(22)7-10-29(11-8-19)12-13-14-4-1-2-9-30(14)17(26-13)18(31)28-16-6-3-5-15(27-16)20(23,24)25/h1-6,9H,7-8,10-12H2,(H,27,28,31)
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n/an/a 1.70n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP level


Bioorg Med Chem Lett 21: 2354-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.082
BindingDB Entry DOI: 10.7270/Q2C829MB
More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo sapiens (Human))
BDBM50446392
PNG
(CHEMBL3109645 | US9181261, 2)
Show SMILES CC(C)N(Cc1c[nH]c2ncccc12)C(=O)Nc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C19H19F3N4O2/c1-12(2)26(11-13-10-24-17-16(13)4-3-9-23-17)18(27)25-14-5-7-15(8-6-14)28-19(20,21)22/h3-10,12H,11H2,1-2H3,(H,23,24)(H,25,27)
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n/an/a 3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human TrkA expressed in human U2OS cells assessed as inhibition of NGF-induced maximum response after 1 hr by beta-galactosidase assay


J Med Chem 57: 5800-16 (2014)


Article DOI: 10.1021/jm5006429
BindingDB Entry DOI: 10.7270/Q2BV7J69
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50340315
PNG
(3-((4,4-difluoropiperidin-1-yl)methyl)-N-((1-(hydr...)
Show SMILES OCC1(CNC(=O)c2nc(CN3CCC(F)(F)CC3)n3ccccc23)CCCC1
Show InChI InChI=1S/C21H28F2N4O2/c22-21(23)8-11-26(12-9-21)13-17-25-18(16-5-1-4-10-27(16)17)19(29)24-14-20(15-28)6-2-3-7-20/h1,4-5,10,28H,2-3,6-9,11-15H2,(H,24,29)
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n/an/a 3n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP level


Bioorg Med Chem Lett 21: 2354-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.082
BindingDB Entry DOI: 10.7270/Q2C829MB
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50005282
PNG
(CHEMBL3114534)
Show SMILES OC(c1nc(C(=O)NC23CC4CC(CC(C4)C2)C3)n2ccccc12)c1cccnc1
Show InChI InChI=1S/C24H26N4O2/c29-21(18-4-3-6-25-14-18)20-19-5-1-2-7-28(19)22(26-20)23(30)27-24-11-15-8-16(12-24)10-17(9-15)13-24/h1-7,14-17,21,29H,8-13H2,(H,27,30)
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n/an/a 4.5n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as forskolin-induced cAMP accumulation after 1 hr


Bioorg Med Chem Lett 24: 1218-21 (2014)


Article DOI: 10.1016/j.bmcl.2013.12.068
BindingDB Entry DOI: 10.7270/Q2FJ2J9K
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50340310
PNG
((2,3-dichlorophenyl)(1-(morpholinomethyl)imidazo[1...)
Show SMILES Clc1cccc(C(=O)c2nc(CN3CCOCC3)c3ccccn23)c1Cl
Show InChI InChI=1S/C19H17Cl2N3O2/c20-14-5-3-4-13(17(14)21)18(25)19-22-15(12-23-8-10-26-11-9-23)16-6-1-2-7-24(16)19/h1-7H,8-12H2
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n/an/a 5n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP level


Bioorg Med Chem Lett 21: 2354-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.082
BindingDB Entry DOI: 10.7270/Q2C829MB
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat))
BDBM50152049
PNG
(3-(2,4-Dichloro-phenyl)-7-dicyclopropylmethyl-8-et...)
Show SMILES CCc1nc2N(CN(C)C(=O)c2n1C(C1CC1)C1CC1)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C21H24Cl2N4O/c1-3-17-24-20-19(27(17)18(12-4-5-12)13-6-7-13)21(28)25(2)11-26(20)16-9-8-14(22)10-15(16)23/h8-10,12-13,18H,3-7,11H2,1-2H3
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n/an/a 6n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptor


J Med Chem 47: 4741-54 (2004)


Article DOI: 10.1021/jm049787k
BindingDB Entry DOI: 10.7270/Q21C1WBB
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50340316
PNG
(3-cyclopropyl-N-(dicyclopropylmethyl)imidazo[1,5-a...)
Show SMILES O=C(NC(C1CC1)C1CC1)c1nc(C2CC2)n2ccccc12
Show InChI InChI=1S/C18H21N3O/c22-18(20-15(11-4-5-11)12-6-7-12)16-14-3-1-2-10-21(14)17(19-16)13-8-9-13/h1-3,10-13,15H,4-9H2,(H,20,22)
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n/an/a 7n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP level


Bioorg Med Chem Lett 21: 2354-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.082
BindingDB Entry DOI: 10.7270/Q2C829MB
More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo sapiens (Human))
BDBM50022675
PNG
(CHEMBL3298268)
Show SMILES CC(C)(C)c1cc(NC(=O)Cn2cc(nn2)-c2ccc(nc2)-n2ccnc2)n(n1)-c1cccnc1
Show InChI InChI=1S/C24H24N10O/c1-24(2,3)20-11-22(34(30-20)18-5-4-8-25-13-18)28-23(35)15-33-14-19(29-31-33)17-6-7-21(27-12-17)32-10-9-26-16-32/h4-14,16H,15H2,1-3H3,(H,28,35)
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n/an/a 7n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human TrkA expressed in human U2OS cells assessed as inhibition of NGF-induced maximum response after 1 hr by beta-galactosidase assay


J Med Chem 57: 5800-16 (2014)


Article DOI: 10.1021/jm5006429
BindingDB Entry DOI: 10.7270/Q2BV7J69
More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo sapiens (Human))
BDBM50022675
PNG
(CHEMBL3298268)
Show SMILES CC(C)(C)c1cc(NC(=O)Cn2cc(nn2)-c2ccc(nc2)-n2ccnc2)n(n1)-c1cccnc1
Show InChI InChI=1S/C24H24N10O/c1-24(2,3)20-11-22(34(30-20)18-5-4-8-25-13-18)28-23(35)15-33-14-19(29-31-33)17-6-7-21(27-12-17)32-10-9-26-16-32/h4-14,16H,15H2,1-3H3,(H,28,35)
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n/an/a 9n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of purified TrkA cytoplasmic domain (unknown origin) by HTRF assay


J Med Chem 57: 5800-16 (2014)


Article DOI: 10.1021/jm5006429
BindingDB Entry DOI: 10.7270/Q2BV7J69
More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo sapiens (Human))
BDBM50022674
PNG
(CHEMBL3298267)
Show SMILES Cc1cn(cn1)-c1ccc(cc1)-c1cn(CC(=O)Nc2cc(nn2-c2ccccc2)C2CC2)nn1
Show InChI InChI=1S/C26H24N8O/c1-18-14-32(17-27-18)21-11-9-20(10-12-21)24-15-33(31-29-24)16-26(35)28-25-13-23(19-7-8-19)30-34(25)22-5-3-2-4-6-22/h2-6,9-15,17,19H,7-8,16H2,1H3,(H,28,35)
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n/an/a 9n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of human TrkA expressed in human U2OS cells assessed as inhibition of NGF-induced maximum response after 1 hr by beta-galactosidase assay


J Med Chem 57: 5800-16 (2014)


Article DOI: 10.1021/jm5006429
BindingDB Entry DOI: 10.7270/Q2BV7J69
More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50235240
PNG
(CHEMBL4065169)
Show SMILES CS(=O)(=O)Nc1cccc(n1)[C@@H](C(c1cccnc1)c1cccnc1)c1ccc(F)cc1
Show InChI InChI=1S/C24H21FN4O2S/c1-32(30,31)29-22-8-2-7-21(28-22)24(17-9-11-20(25)12-10-17)23(18-5-3-13-26-15-18)19-6-4-14-27-16-19/h2-16,23-24H,1H3,(H,28,29)/t24-/m0/s1
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n/an/a 9n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
In vitro antagonistic activity towards LTB4 receptor was evaluated by inhibition of binding of [3H]LTB4 to human neutrophils


Bioorg Med Chem Lett 27: 1062-1069 (2017)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat))
BDBM50152033
PNG
(7-(1-Cyclopropyl-butyl)-3-(2,4-dichloro-phenyl)-8-...)
Show SMILES CCCC(C1CC1)n1c(CC)nc2N(CN(C)C(=O)c12)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C21H26Cl2N4O/c1-4-6-16(13-7-8-13)27-18(5-2)24-20-19(27)21(28)25(3)12-26(20)17-10-9-14(22)11-15(17)23/h9-11,13,16H,4-8,12H2,1-3H3
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n/an/a 10n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptor


J Med Chem 47: 4741-54 (2004)


Article DOI: 10.1021/jm049787k
BindingDB Entry DOI: 10.7270/Q21C1WBB
More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo sapiens (Human))
BDBM50022670
PNG
(CHEMBL3297748)
Show SMILES CN1CCN(CC1)c1ccc(Nc2ncnc3ccc(NCc4cccc(Cl)c4)nc23)cc1
Show InChI InChI=1S/C25H26ClN7/c1-32-11-13-33(14-12-32)21-7-5-20(6-8-21)30-25-24-22(28-17-29-25)9-10-23(31-24)27-16-18-3-2-4-19(26)15-18/h2-10,15,17H,11-14,16H2,1H3,(H,27,31)(H,28,29,30)
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n/an/a 11n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of purified TrkA cytoplasmic domain (unknown origin) by HTRF assay


J Med Chem 57: 5800-16 (2014)


Article DOI: 10.1021/jm5006429
BindingDB Entry DOI: 10.7270/Q2BV7J69
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM50340310
PNG
((2,3-dichlorophenyl)(1-(morpholinomethyl)imidazo[1...)
Show SMILES Clc1cccc(C(=O)c2nc(CN3CCOCC3)c3ccccn23)c1Cl
Show InChI InChI=1S/C19H17Cl2N3O2/c20-14-5-3-4-13(17(14)21)18(25)19-22-15(12-23-8-10-26-11-9-23)16-6-1-2-7-24(16)19/h1-7H,8-12H2
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n/an/a 11n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at rat CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP level


Bioorg Med Chem Lett 21: 2354-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.082
BindingDB Entry DOI: 10.7270/Q2C829MB
More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50235240
PNG
(CHEMBL4065169)
Show SMILES CS(=O)(=O)Nc1cccc(n1)[C@@H](C(c1cccnc1)c1cccnc1)c1ccc(F)cc1
Show InChI InChI=1S/C24H21FN4O2S/c1-32(30,31)29-22-8-2-7-21(28-22)24(17-9-11-20(25)12-10-17)23(18-5-3-13-26-15-18)19-6-4-14-27-16-19/h2-16,23-24H,1H3,(H,28,29)/t24-/m0/s1
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n/an/a 11n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial myocytes by voltage-patch clamp electrophysiology method


Bioorg Med Chem Lett 27: 1062-1069 (2017)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50235250
PNG
(CHEMBL4104525)
Show SMILES O[C@H](C(c1cccnc1)c1cccnc1)c1cccnc1-c1cc(Cl)cc(Cl)c1
Show InChI InChI=1S/C23H17Cl2N3O/c24-18-10-17(11-19(25)12-18)22-20(6-3-9-28-22)23(29)21(15-4-1-7-26-13-15)16-5-2-8-27-14-16/h1-14,21,23,29H/t23-/m0/s1
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Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of Kv1.5 mediated ultra-rapid delayed rectifier current Ikur in human atrial myocytes by voltage-patch clamp electrophysiology method


Bioorg Med Chem Lett 27: 1062-1069 (2017)

More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo sapiens (Human))
BDBM50446392
PNG
(CHEMBL3109645 | US9181261, 2)
Show SMILES CC(C)N(Cc1c[nH]c2ncccc12)C(=O)Nc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C19H19F3N4O2/c1-12(2)26(11-13-10-24-17-16(13)4-3-9-23-17)18(27)25-14-5-7-15(8-6-14)28-19(20,21)22/h3-10,12H,11H2,1-2H3,(H,23,24)(H,25,27)
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n/an/a 11n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of phsophorylated TrkA (unknown origin) assessed as inhibition of fluorescently-labelled substrate phosphorylation by CALIPER enzymatic as...


J Med Chem 57: 5800-16 (2014)


Article DOI: 10.1021/jm5006429
BindingDB Entry DOI: 10.7270/Q2BV7J69
More data for this
Ligand-Target Pair
High affinity nerve growth factor receptor


(Homo sapiens (Human))
BDBM50022671
PNG
(CHEMBL3298265)
Show SMILES Cc1cn2cc(CNc3ncnc4ccc(nc34)N3CCC[C@@H]3c3cc(F)ccc3F)nc2s1
Show InChI InChI=1S/C24H21F2N7S/c1-14-11-32-12-16(30-24(32)34-14)10-27-23-22-19(28-13-29-23)6-7-21(31-22)33-8-2-3-20(33)17-9-15(25)4-5-18(17)26/h4-7,9,11-13,20H,2-3,8,10H2,1H3,(H,27,28,29)/t20-/m1/s1
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n/an/a 13n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of phsophorylated TrkA (unknown origin) assessed as inhibition of fluorescently-labelled substrate phosphorylation by CALIPER enzymatic as...


J Med Chem 57: 5800-16 (2014)


Article DOI: 10.1021/jm5006429
BindingDB Entry DOI: 10.7270/Q2BV7J69
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat))
BDBM50152054
PNG
(7-(1-Cyclopropyl-propyl)-3-(2,4-dichloro-phenyl)-8...)
Show SMILES CCC(C1CC1)n1c(CC)nc2N(CN(C)C(=O)c12)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C20H24Cl2N4O/c1-4-15(12-6-7-12)26-17(5-2)23-19-18(26)20(27)24(3)11-25(19)16-9-8-13(21)10-14(16)22/h8-10,12,15H,4-7,11H2,1-3H3
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n/an/a 14n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptor


J Med Chem 47: 4741-54 (2004)


Article DOI: 10.1021/jm049787k
BindingDB Entry DOI: 10.7270/Q21C1WBB
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat))
BDBM50152059
PNG
(3-(2,4-Dichloro-phenyl)-8-ethyl-7-(1-ethyl-pentyl)...)
Show SMILES CCCCC(CC)n1c(CC)nc2N(CN(C)C(=O)c12)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C21H28Cl2N4O/c1-5-8-9-15(6-2)27-18(7-3)24-20-19(27)21(28)25(4)13-26(20)17-11-10-14(22)12-16(17)23/h10-12,15H,5-9,13H2,1-4H3
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n/an/a 18n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptor


J Med Chem 47: 4741-54 (2004)


Article DOI: 10.1021/jm049787k
BindingDB Entry DOI: 10.7270/Q21C1WBB
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50340318
PNG
((R)-3-morpholino-N-(2,2,2-trifluoro-1-(pyridin-2-y...)
Show SMILES FC(F)(F)[C@H](NC(=O)c1nc(N2CCOCC2)n2ccccc12)c1ccccn1
Show InChI InChI=1S/C19H18F3N5O2/c20-19(21,22)16(13-5-1-3-7-23-13)25-17(28)15-14-6-2-4-8-27(14)18(24-15)26-9-11-29-12-10-26/h1-8,16H,9-12H2,(H,25,28)/t16-/m1/s1
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n/an/a 21n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP level


Bioorg Med Chem Lett 21: 2354-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.082
BindingDB Entry DOI: 10.7270/Q2C829MB
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50340317
PNG
(3-cyclopropyl-N-neopentylimidazo[1,5-a]pyridine-1-...)
Show SMILES CC(C)(C)CNC(=O)c1nc(C2CC2)n2ccccc12
Show InChI InChI=1S/C16H21N3O/c1-16(2,3)10-17-15(20)13-12-6-4-5-9-19(12)14(18-13)11-7-8-11/h4-6,9,11H,7-8,10H2,1-3H3,(H,17,20)
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n/an/a 21n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Agonist activity at human CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated cAMP level


Bioorg Med Chem Lett 21: 2354-8 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.082
BindingDB Entry DOI: 10.7270/Q2C829MB
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat))
BDBM50152043
PNG
(8-Ethyl-1-methyl-7-(1-propyl-butyl)-3-(2,4,6-trime...)
Show SMILES CCCC(CCC)n1c(CC)nc2N(CN(C)C(=O)c12)c1c(C)cc(C)cc1C
Show InChI InChI=1S/C24H36N4O/c1-8-11-19(12-9-2)28-20(10-3)25-23-22(28)24(29)26(7)15-27(23)21-17(5)13-16(4)14-18(21)6/h13-14,19H,8-12,15H2,1-7H3
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n/an/a 22n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptor


J Med Chem 47: 4741-54 (2004)


Article DOI: 10.1021/jm049787k
BindingDB Entry DOI: 10.7270/Q21C1WBB
More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50235255
PNG
(CHEMBL4085436)
Show SMILES Clc1ccccc1-c1ncccc1CC(c1cccnc1)c1cccnc1
Show InChI InChI=1S/C23H18ClN3/c24-22-10-2-1-9-20(22)23-17(6-5-13-27-23)14-21(18-7-3-11-25-15-18)19-8-4-12-26-16-19/h1-13,15-16,21H,14H2
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n/an/a 23n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of Kv1.5 (unknown origin)


Bioorg Med Chem Lett 27: 1062-1069 (2017)

More data for this
Ligand-Target Pair
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50235259
PNG
(CHEMBL4105245)
Show SMILES Clc1ccccc1-c1ncccc1CC(c1cccnc1)c1cccnc1Cl
Show InChI InChI=1S/C23H17Cl2N3/c24-21-10-2-1-8-19(21)22-16(6-4-12-27-22)14-20(17-7-3-11-26-15-17)18-9-5-13-28-23(18)25/h1-13,15,20H,14H2
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n/an/a 26n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of Kv1.5 (unknown origin)


Bioorg Med Chem Lett 27: 1062-1069 (2017)

More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat))
BDBM50152031
PNG
(7-(1-Cyclobutyl-ethyl)-3-(2,4-dichloro-phenyl)-8-e...)
Show SMILES CCc1nc2N(CN(C)C(=O)c2n1C(C)C1CCC1)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C20H24Cl2N4O/c1-4-17-23-19-18(26(17)12(2)13-6-5-7-13)20(27)24(3)11-25(19)16-9-8-14(21)10-15(16)22/h8-10,12-13H,4-7,11H2,1-3H3
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n/an/a 26n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptor


J Med Chem 47: 4741-54 (2004)


Article DOI: 10.1021/jm049787k
BindingDB Entry DOI: 10.7270/Q21C1WBB
More data for this
Ligand-Target Pair
Corticotropin releasing factor receptor


(Rattus norvegicus (rat))
BDBM50152055
PNG
(3-(2-Chloro-4-methoxy-phenyl)-8-ethyl-1-methyl-7-(...)
Show SMILES CCCC(CCC)n1c(CC)nc2N(CN(C)C(=O)c12)c1ccc(OC)cc1Cl
Show InChI InChI=1S/C22H31ClN4O2/c1-6-9-15(10-7-2)27-19(8-3)24-21-20(27)22(28)25(4)14-26(21)18-12-11-16(29-5)13-17(18)23/h11-13,15H,6-10,14H2,1-5H3
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n/an/a 27n/an/an/an/an/an/a



Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of [125I]- Ovine CRF binding to rat frontal cortex corticotropin releasing factor 1 receptor


J Med Chem 47: 4741-54 (2004)


Article DOI: 10.1021/jm049787k
BindingDB Entry DOI: 10.7270/Q21C1WBB
More data for this
Ligand-Target Pair
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