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Compile Data Set for Download or QSAR

Found 161 hits with Last Name = 'rudolph' and Initial = 'mj'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50109377
PNG
(4-[4-(3,4-Dimethoxy-phenyl)-thiazol-2-yl]-5-methyl...)
Show SMILES COc1ccc(cc1OC)-c1csc(n1)-c1cc(sc1SC)C(N)=N
Show InChI InChI=1S/C17H17N3O2S3/c1-21-12-5-4-9(6-13(12)22-2)11-8-24-16(20-11)10-7-14(15(18)19)25-17(10)23-3/h4-8H,1-3H3,(H3,18,19)
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58n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of Human kidney cell urokinase


Bioorg Med Chem Lett 12: 491-5 (2002)


Article DOI: 10.1016/s0960-894x(01)00787-9
BindingDB Entry DOI: 10.7270/Q2H994H5
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098163
PNG
(5-Methylsulfanyl-4-[2-(4-phenoxy-phenylamino)-thia...)
Show SMILES CSc1sc(cc1-c1csc(Nc2ccc(Oc3ccccc3)cc2)n1)C(N)=N
Show InChI InChI=1S/C21H18N4OS3/c1-27-20-16(11-18(29-20)19(22)23)17-12-28-21(25-17)24-13-7-9-15(10-8-13)26-14-5-3-2-4-6-14/h2-12H,1H3,(H3,22,23)(H,24,25)
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60n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098169
PNG
(5-Methylsulfanyl-4-[2-(4-phenylamino-phenylamino)-...)
Show SMILES CSc1sc(cc1-c1csc(Nc2ccc(Nc3ccccc3)cc2)n1)C(N)=N
Show InChI InChI=1S/C21H19N5S3/c1-27-20-16(11-18(29-20)19(22)23)17-12-28-21(26-17)25-15-9-7-14(8-10-15)24-13-5-3-2-4-6-13/h2-12,24H,1H3,(H3,22,23)(H,25,26)
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70n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098144
PNG
(5-Methyl-4-[2-(4-phenoxy-phenylamino)-thiazol-4-yl...)
Show SMILES Cc1sc(cc1-c1csc(Nc2ccc(Oc3ccccc3)cc2)n1)C(N)=N
Show InChI InChI=1S/C21H18N4OS2/c1-13-17(11-19(28-13)20(22)23)18-12-27-21(25-18)24-14-7-9-16(10-8-14)26-15-5-3-2-4-6-15/h2-12H,1H3,(H3,22,23)(H,24,25)
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80n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50099921
PNG
(5-Methylsulfanyl-4-(4-phenyl-thiazol-2-yl)-thiophe...)
Show SMILES CSc1sc(cc1-c1nc(cs1)-c1ccccc1)C(N)=N
Show InChI InChI=1S/C15H13N3S3/c1-19-15-10(7-12(21-15)13(16)17)14-18-11(8-20-14)9-5-3-2-4-6-9/h2-8H,1H3,(H3,16,17)
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90n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against serine protease urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 1379-82 (2001)


Article DOI: 10.1016/s0960-894x(01)00247-5
BindingDB Entry DOI: 10.7270/Q24M93S1
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50099921
PNG
(5-Methylsulfanyl-4-(4-phenyl-thiazol-2-yl)-thiophe...)
Show SMILES CSc1sc(cc1-c1nc(cs1)-c1ccccc1)C(N)=N
Show InChI InChI=1S/C15H13N3S3/c1-19-15-10(7-12(21-15)13(16)17)14-18-11(8-20-14)9-5-3-2-4-6-9/h2-8H,1H3,(H3,16,17)
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101n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of Human kidney cell urokinase


Bioorg Med Chem Lett 12: 491-5 (2002)


Article DOI: 10.1016/s0960-894x(01)00787-9
BindingDB Entry DOI: 10.7270/Q2H994H5
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50099900
PNG
(4-[4-(4-Chloro-phenyl)-thiazol-2-yl]-5-methylsulfa...)
Show SMILES CSc1sc(cc1-c1nc(cs1)-c1ccc(Cl)cc1)C(N)=N
Show InChI InChI=1S/C15H12ClN3S3/c1-20-15-10(6-12(22-15)13(17)18)14-19-11(7-21-14)8-2-4-9(16)5-3-8/h2-7H,1H3,(H3,17,18)
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102n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of Human kidney cell urokinase


Bioorg Med Chem Lett 12: 491-5 (2002)


Article DOI: 10.1016/s0960-894x(01)00787-9
BindingDB Entry DOI: 10.7270/Q2H994H5
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50109381
PNG
(5-Methyl-4-(4-phenyl-thiazol-2-yl)-thiophene-2-car...)
Show SMILES Cc1sc(cc1-c1nc(cs1)-c1ccccc1)C(N)=N
Show InChI InChI=1S/C15H13N3S2/c1-9-11(7-13(20-9)14(16)17)15-18-12(8-19-15)10-5-3-2-4-6-10/h2-8H,1H3,(H3,16,17)
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103n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of Human kidney cell urokinase


Bioorg Med Chem Lett 12: 491-5 (2002)


Article DOI: 10.1016/s0960-894x(01)00787-9
BindingDB Entry DOI: 10.7270/Q2H994H5
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098141
PNG
(4-{2-[4-(4-Chloro-phenoxy)-phenylamino]-thiazol-4-...)
Show SMILES CSc1sc(cc1-c1csc(Nc2ccc(Oc3ccc(Cl)cc3)cc2)n1)C(N)=N
Show InChI InChI=1S/C21H17ClN4OS3/c1-28-20-16(10-18(30-20)19(23)24)17-11-29-21(26-17)25-13-4-8-15(9-5-13)27-14-6-2-12(22)3-7-14/h2-11H,1H3,(H3,23,24)(H,25,26)
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110n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098127
PNG
(4-[2-(4-Cyclohexyl-phenylamino)-thiazol-4-yl]-5-me...)
Show SMILES CSc1sc(cc1-c1csc(Nc2ccc(cc2)C2CCCCC2)n1)C(N)=N
Show InChI InChI=1S/C21H24N4S3/c1-26-20-16(11-18(28-20)19(22)23)17-12-27-21(25-17)24-15-9-7-14(8-10-15)13-5-3-2-4-6-13/h7-13H,2-6H2,1H3,(H3,22,23)(H,24,25)
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110n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50109378
PNG
(5-Ethyl-4-(4-phenyl-thiazol-2-yl)-thiophene-2-carb...)
Show SMILES CCc1sc(cc1-c1nc(cs1)-c1ccccc1)C(N)=N
Show InChI InChI=1S/C16H15N3S2/c1-2-13-11(8-14(21-13)15(17)18)16-19-12(9-20-16)10-6-4-3-5-7-10/h3-9H,2H2,1H3,(H3,17,18)
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138n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of Human kidney cell urokinase


Bioorg Med Chem Lett 12: 491-5 (2002)


Article DOI: 10.1016/s0960-894x(01)00787-9
BindingDB Entry DOI: 10.7270/Q2H994H5
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098139
PNG
(5-Methylsulfanyl-4-[2-(3,4,5-trimethoxy-phenylamin...)
Show SMILES COc1cc(Nc2nc(cs2)-c2cc(sc2SC)C(N)=N)cc(OC)c1OC
Show InChI InChI=1S/C18H20N4O3S3/c1-23-12-5-9(6-13(24-2)15(12)25-3)21-18-22-11(8-27-18)10-7-14(16(19)20)28-17(10)26-4/h5-8H,1-4H3,(H3,19,20)(H,21,22)
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160n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50109376
PNG
(4-[4-(3,4-Dimethoxy-phenyl)-thiazol-2-yl]-5-methyl...)
Show SMILES COc1ccc(cc1OC)-c1csc(n1)-c1cc(sc1C)C(N)=N
Show InChI InChI=1S/C17H17N3O2S2/c1-9-11(7-15(24-9)16(18)19)17-20-12(8-23-17)10-4-5-13(21-2)14(6-10)22-3/h4-8H,1-3H3,(H3,18,19)
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169n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of Human kidney cell urokinase


Bioorg Med Chem Lett 12: 491-5 (2002)


Article DOI: 10.1016/s0960-894x(01)00787-9
BindingDB Entry DOI: 10.7270/Q2H994H5
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098132
PNG
(5-Methyl-4-(2-phenylamino-thiazol-4-yl)-thiophene-...)
Show SMILES Cc1sc(cc1-c1csc(Nc2ccccc2)n1)C(N)=N
Show InChI InChI=1S/C15H14N4S2/c1-9-11(7-13(21-9)14(16)17)12-8-20-15(19-12)18-10-5-3-2-4-6-10/h2-8H,1H3,(H3,16,17)(H,18,19)
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170n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098133
PNG
(4-[2-(4-Benzyl-phenylamino)-thiazol-4-yl]-5-methyl...)
Show SMILES CSc1sc(cc1-c1csc(Nc2ccc(Cc3ccccc3)cc2)n1)C(N)=N
Show InChI InChI=1S/C22H20N4S3/c1-27-21-17(12-19(29-21)20(23)24)18-13-28-22(26-18)25-16-9-7-15(8-10-16)11-14-5-3-2-4-6-14/h2-10,12-13H,11H2,1H3,(H3,23,24)(H,25,26)
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180n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098131
PNG
(5-Methylsulfanyl-4-[2-(4-phenylazo-phenylamino)-th...)
Show SMILES CSc1sc(cc1-c1csc(Nc2ccc(cc2)\N=N\c2ccccc2)n1)C(N)=N
Show InChI InChI=1S/C21H18N6S3/c1-28-20-16(11-18(30-20)19(22)23)17-12-29-21(25-17)24-13-7-9-15(10-8-13)27-26-14-5-3-2-4-6-14/h2-12H,1H3,(H3,22,23)(H,24,25)/b27-26+
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180n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098147
PNG
(4-[2-(4-Benzyloxy-phenylamino)-thiazol-4-yl]-5-met...)
Show SMILES CSc1sc(cc1-c1csc(Nc2ccc(OCc3ccccc3)cc2)n1)C(N)=N
Show InChI InChI=1S/C22H20N4OS3/c1-28-21-17(11-19(30-21)20(23)24)18-13-29-22(26-18)25-15-7-9-16(10-8-15)27-12-14-5-3-2-4-6-14/h2-11,13H,12H2,1H3,(H3,23,24)(H,25,26)
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180n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50099932
PNG
(5-Methylsulfanyl-4-(2-phenyl-thiazol-4-yl)-thiophe...)
Show SMILES CSc1sc(cc1-c1csc(n1)-c1ccccc1)C(N)=N
Show InChI InChI=1S/C15H13N3S3/c1-19-15-10(7-12(21-15)13(16)17)11-8-20-14(18-11)9-5-3-2-4-6-9/h2-8H,1H3,(H3,16,17)
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200n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against serine protease urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 1379-82 (2001)


Article DOI: 10.1016/s0960-894x(01)00247-5
BindingDB Entry DOI: 10.7270/Q24M93S1
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098166
PNG
(5-Methylsulfanyl-4-(2-phenylamino-thiazol-4-yl)-th...)
Show SMILES CSc1sc(cc1-c1csc(Nc2ccccc2)n1)C(N)=N
Show InChI InChI=1S/C15H14N4S3/c1-20-14-10(7-12(22-14)13(16)17)11-8-21-15(19-11)18-9-5-3-2-4-6-9/h2-8H,1H3,(H3,16,17)(H,18,19)
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200n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098149
PNG
(4-[2-(2-Fluoro-phenylamino)-thiazol-4-yl]-5-methyl...)
Show SMILES CSc1sc(cc1-c1csc(Nc2ccccc2F)n1)C(N)=N
Show InChI InChI=1S/C15H13FN4S3/c1-21-14-8(6-12(23-14)13(17)18)11-7-22-15(20-11)19-10-5-3-2-4-9(10)16/h2-7H,1H3,(H3,17,18)(H,19,20)
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240n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098150
PNG
(4-[2-(4-Chloro-2-methyl-phenylamino)-thiazol-4-yl]...)
Show SMILES CSc1sc(cc1-c1csc(Nc2ccc(Cl)cc2C)n1)C(N)=N
Show InChI InChI=1S/C16H15ClN4S3/c1-8-5-9(17)3-4-11(8)20-16-21-12(7-23-16)10-6-13(14(18)19)24-15(10)22-2/h3-7H,1-2H3,(H3,18,19)(H,20,21)
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280n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098151
PNG
(4-[2-(2-Bromo-phenylamino)-thiazol-4-yl]-5-methyls...)
Show SMILES CSc1sc(cc1-c1csc(Nc2ccccc2Br)n1)C(N)=N
Show InChI InChI=1S/C15H13BrN4S3/c1-21-14-8(6-12(23-14)13(17)18)11-7-22-15(20-11)19-10-5-3-2-4-9(10)16/h2-7H,1H3,(H3,17,18)(H,19,20)
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280n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098142
PNG
(4-[2-(3-Methoxy-phenylamino)-thiazol-4-yl]-5-methy...)
Show SMILES COc1cccc(Nc2nc(cs2)-c2cc(sc2SC)C(N)=N)c1
Show InChI InChI=1S/C16H16N4OS3/c1-21-10-5-3-4-9(6-10)19-16-20-12(8-23-16)11-7-13(14(17)18)24-15(11)22-2/h3-8H,1-2H3,(H3,17,18)(H,19,20)
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280n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098158
PNG
(4-[2-(2,3-Dimethyl-phenylamino)-thiazol-4-yl]-5-me...)
Show SMILES CSc1sc(cc1-c1csc(Nc2cccc(C)c2C)n1)C(N)=N
Show InChI InChI=1S/C17H18N4S3/c1-9-5-4-6-12(10(9)2)20-17-21-13(8-23-17)11-7-14(15(18)19)24-16(11)22-3/h4-8H,1-3H3,(H3,18,19)(H,20,21)
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280n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098164
PNG
(4-[2-(4-Methoxy-phenylamino)-thiazol-4-yl]-5-methy...)
Show SMILES COc1ccc(Nc2nc(cs2)-c2cc(sc2SC)C(N)=N)cc1
Show InChI InChI=1S/C16H16N4OS3/c1-21-10-5-3-9(4-6-10)19-16-20-12(8-23-16)11-7-13(14(17)18)24-15(11)22-2/h3-8H,1-2H3,(H3,17,18)(H,19,20)
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280n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098140
PNG
(4-[2-(4-Dimethylamino-phenylamino)-thiazol-4-yl]-5...)
Show SMILES CSc1sc(cc1-c1csc(Nc2ccc(cc2)N(C)C)n1)C(N)=N
Show InChI InChI=1S/C17H19N5S3/c1-22(2)11-6-4-10(5-7-11)20-17-21-13(9-24-17)12-8-14(15(18)19)25-16(12)23-3/h4-9H,1-3H3,(H3,18,19)(H,20,21)
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310n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098137
PNG
(2-amidino-4-iodobenzothiophene | 4-Iodo-benzo[b]th...)
Show SMILES NC(=N)c1cc2c(I)cccc2s1
Show InChI InChI=1S/C9H7IN2S/c10-6-2-1-3-7-5(6)4-8(13-7)9(11)12/h1-4H,(H3,11,12)
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320n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of Human kidney cell urokinase


Bioorg Med Chem Lett 12: 491-5 (2002)


Article DOI: 10.1016/s0960-894x(01)00787-9
BindingDB Entry DOI: 10.7270/Q2H994H5
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098137
PNG
(2-amidino-4-iodobenzothiophene | 4-Iodo-benzo[b]th...)
Show SMILES NC(=N)c1cc2c(I)cccc2s1
Show InChI InChI=1S/C9H7IN2S/c10-6-2-1-3-7-5(6)4-8(13-7)9(11)12/h1-4H,(H3,11,12)
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320n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098143
PNG
(5-Methylsulfanyl-4-[2-(3-phenyl-propylamino)-thiaz...)
Show SMILES CSc1sc(cc1-c1csc(NCCCc2ccccc2)n1)C(N)=N
Show InChI InChI=1S/C18H20N4S3/c1-23-17-13(10-15(25-17)16(19)20)14-11-24-18(22-14)21-9-5-8-12-6-3-2-4-7-12/h2-4,6-7,10-11H,5,8-9H2,1H3,(H3,19,20)(H,21,22)
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350n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098152
PNG
(5-Methylsulfanyl-4-{2-[4-(piperidine-1-sulfonyl)-p...)
Show SMILES CSc1sc(cc1-c1csc(Nc2ccc(cc2)S(=O)(=O)N2CCCCC2)n1)C(N)=N
Show InChI InChI=1S/C20H23N5O2S4/c1-28-19-15(11-17(30-19)18(21)22)16-12-29-20(24-16)23-13-5-7-14(8-6-13)31(26,27)25-9-3-2-4-10-25/h5-8,11-12H,2-4,9-10H2,1H3,(H3,21,22)(H,23,24)
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400n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098138
PNG
(4-[2-(2-Bromo-4-methyl-phenylamino)-thiazol-4-yl]-...)
Show SMILES CSc1sc(cc1-c1csc(Nc2ccc(C)cc2Br)n1)C(N)=N
Show InChI InChI=1S/C16H15BrN4S3/c1-8-3-4-11(10(17)5-8)20-16-21-12(7-23-16)9-6-13(14(18)19)24-15(9)22-2/h3-7H,1-2H3,(H3,18,19)(H,20,21)
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430n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098162
PNG
(4-[2-(3-Chloro-2-methyl-phenylamino)-thiazol-4-yl]...)
Show SMILES CSc1sc(cc1-c1csc(Nc2cccc(Cl)c2C)n1)C(N)=N
Show InChI InChI=1S/C16H15ClN4S3/c1-8-10(17)4-3-5-11(8)20-16-21-12(7-23-16)9-6-13(14(18)19)24-15(9)22-2/h3-7H,1-2H3,(H3,18,19)(H,20,21)
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440n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098153
PNG
(4-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-thiazol...)
Show SMILES COc1ccc(cc1)N1CCN(CC1)c1nc(cs1)-c1cc(sc1SC)C(N)=N
Show InChI InChI=1S/C20H23N5OS3/c1-26-14-5-3-13(4-6-14)24-7-9-25(10-8-24)20-23-16(12-28-20)15-11-17(18(21)22)29-19(15)27-2/h3-6,11-12H,7-10H2,1-2H3,(H3,21,22)
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480n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098156
PNG
(5-Methylsulfanyl-4-[2-(naphthalen-1-ylamino)-thiaz...)
Show SMILES CSc1sc(cc1-c1csc(Nc2cccc3ccccc23)n1)C(N)=N
Show InChI InChI=1S/C19H16N4S3/c1-24-18-13(9-16(26-18)17(20)21)15-10-25-19(23-15)22-14-8-4-6-11-5-2-3-7-12(11)14/h2-10H,1H3,(H3,20,21)(H,22,23)
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500n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098145
PNG
(4-[2-(Benzo[1,3]dioxol-5-ylamino)-thiazol-4-yl]-5-...)
Show SMILES CSc1sc(cc1-c1csc(Nc2ccc3OCOc3c2)n1)C(N)=N
Show InChI InChI=1S/C16H14N4O2S3/c1-23-15-9(5-13(25-15)14(17)18)10-6-24-16(20-10)19-8-2-3-11-12(4-8)22-7-21-11/h2-6H,7H2,1H3,(H3,17,18)(H,19,20)
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520n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50099926
PNG
(4-((E)-2-Benzo[1,3]dioxol-5-yl-vinyl)-benzo[b]thio...)
Show SMILES NC(=N)c1cc2c(\C=C\c3ccc4OCOc4c3)cccc2s1
Show InChI InChI=1S/C18H14N2O2S/c19-18(20)17-9-13-12(2-1-3-16(13)23-17)6-4-11-5-7-14-15(8-11)22-10-21-14/h1-9H,10H2,(H3,19,20)/b6-4+
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530n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against serine protease urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 1379-82 (2001)


Article DOI: 10.1016/s0960-894x(01)00247-5
BindingDB Entry DOI: 10.7270/Q24M93S1
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50109379
PNG
(5-Methoxy-4-(4-phenyl-thiazol-2-yl)-thiophene-2-ca...)
Show SMILES COc1sc(cc1-c1nc(cs1)-c1ccccc1)C(N)=N
Show InChI InChI=1S/C15H13N3OS2/c1-19-15-10(7-12(21-15)13(16)17)14-18-11(8-20-14)9-5-3-2-4-6-9/h2-8H,1H3,(H3,16,17)
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531n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of Human kidney cell urokinase


Bioorg Med Chem Lett 12: 491-5 (2002)


Article DOI: 10.1016/s0960-894x(01)00787-9
BindingDB Entry DOI: 10.7270/Q2H994H5
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50099922
PNG
(5-Methylsulfanyl-4-phenyl-thiophene-2-carboxamidin...)
Show SMILES CSc1sc(cc1-c1ccccc1)C(N)=N
Show InChI InChI=1S/C12H12N2S2/c1-15-12-9(7-10(16-12)11(13)14)8-5-3-2-4-6-8/h2-7H,1H3,(H3,13,14)
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600n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against serine protease urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 1379-82 (2001)


Article DOI: 10.1016/s0960-894x(01)00247-5
BindingDB Entry DOI: 10.7270/Q24M93S1
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098155
PNG
(4-[2-(4-Methyl-benzylamino)-thiazol-4-yl]-5-methyl...)
Show SMILES CSc1sc(cc1-c1csc(NCc2ccc(C)cc2)n1)C(N)=N
Show InChI InChI=1S/C17H18N4S3/c1-10-3-5-11(6-4-10)8-20-17-21-13(9-23-17)12-7-14(15(18)19)24-16(12)22-2/h3-7,9H,8H2,1-2H3,(H3,18,19)(H,20,21)
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640n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098148
PNG
(4-[2-(2,5-Dimethoxy-phenylamino)-thiazol-4-yl]-5-m...)
Show SMILES COc1ccc(OC)c(Nc2nc(cs2)-c2cc(sc2SC)C(N)=N)c1
Show InChI InChI=1S/C17H18N4O2S3/c1-22-9-4-5-13(23-2)11(6-9)20-17-21-12(8-25-17)10-7-14(15(18)19)26-16(10)24-3/h4-8H,1-3H3,(H3,18,19)(H,20,21)
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660n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098128
PNG
(4-[2-(2-Isopropyl-phenylamino)-thiazol-4-yl]-5-met...)
Show SMILES CSc1sc(cc1-c1csc(Nc2ccccc2C(C)C)n1)C(N)=N
Show InChI InChI=1S/C18H20N4S3/c1-10(2)11-6-4-5-7-13(11)21-18-22-14(9-24-18)12-8-15(16(19)20)25-17(12)23-3/h4-10H,1-3H3,(H3,19,20)(H,21,22)
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700n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (Human))
BDBM50099903
PNG
(4-[4-(3-Methoxy-phenyl)-thiazol-2-yl]-5-methylsulf...)
Show SMILES COc1cccc(c1)-c1csc(n1)-c1cc(sc1SC)C(N)=N
Show InChI InChI=1S/C16H15N3OS3/c1-20-10-5-3-4-9(6-10)12-8-22-15(19-12)11-7-13(14(17)18)23-16(11)21-2/h3-8H,1-2H3,(H3,17,18)
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860n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against Trypsin


Bioorg Med Chem Lett 11: 1379-82 (2001)


Article DOI: 10.1016/s0960-894x(01)00247-5
BindingDB Entry DOI: 10.7270/Q24M93S1
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (Human))
BDBM50099911
PNG
(4-(4-Benzo[1,3]dioxol-5-yl-thiazol-2-yl)-5-methyls...)
Show SMILES CSc1sc(cc1-c1nc(cs1)-c1ccc2OCOc2c1)C(N)=N
Show InChI InChI=1S/C16H13N3O2S3/c1-22-16-9(5-13(24-16)14(17)18)15-19-10(6-23-15)8-2-3-11-12(4-8)21-7-20-11/h2-6H,7H2,1H3,(H3,17,18)
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880n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against Trypsin


Bioorg Med Chem Lett 11: 1379-82 (2001)


Article DOI: 10.1016/s0960-894x(01)00247-5
BindingDB Entry DOI: 10.7270/Q24M93S1
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098160
PNG
(5-Methylsulfanyl-4-{2-[4-(5-trifluoromethyl-pyridi...)
Show SMILES CSc1sc(cc1-c1csc(Nc2ccc(Oc3ccc(cn3)C(F)(F)F)cc2)n1)C(N)=N
Show InChI InChI=1S/C21H16F3N5OS3/c1-31-19-14(8-16(33-19)18(25)26)15-10-32-20(29-15)28-12-3-5-13(6-4-12)30-17-7-2-11(9-27-17)21(22,23)24/h2-10H,1H3,(H3,25,26)(H,28,29)
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910n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Trypsin-1


(Homo sapiens (Human))
BDBM50099902
PNG
(4-[4-(3-Hydroxy-phenyl)-thiazol-2-yl]-5-methylsulf...)
Show SMILES CSc1sc(cc1-c1nc(cs1)-c1cccc(O)c1)C(N)=N
Show InChI InChI=1S/C15H13N3OS3/c1-20-15-10(6-12(22-15)13(16)17)14-18-11(7-21-14)8-3-2-4-9(19)5-8/h2-7,19H,1H3,(H3,16,17)
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930n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against Trypsin


Bioorg Med Chem Lett 11: 1379-82 (2001)


Article DOI: 10.1016/s0960-894x(01)00247-5
BindingDB Entry DOI: 10.7270/Q24M93S1
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator/surface receptor


(Homo sapiens (Human))
BDBM50099908
PNG
(5-Methylsulfanyl-4-(4-methyl-thiazol-2-yl)-thiophe...)
Show SMILES CSc1sc(cc1-c1nc(C)cs1)C(N)=N
Show InChI InChI=1S/C10H11N3S3/c1-5-4-15-9(13-5)6-3-7(8(11)12)16-10(6)14-2/h3-4H,1-2H3,(H3,11,12)
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1.00E+3n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against serine protease urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 1379-82 (2001)


Article DOI: 10.1016/s0960-894x(01)00247-5
BindingDB Entry DOI: 10.7270/Q24M93S1
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098129
PNG
(2-{3-[4-(5-Carbamimidoyl-2-methylsulfanyl-thiophen...)
Show SMILES CSc1sc(cc1-c1csc(Nc2cccc(OCC(N)=O)c2)n1)C(N)=N
Show InChI InChI=1S/C17H17N5O2S3/c1-25-16-11(6-13(27-16)15(19)20)12-8-26-17(22-12)21-9-3-2-4-10(5-9)24-7-14(18)23/h2-6,8H,7H2,1H3,(H2,18,23)(H3,19,20)(H,21,22)
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1.02E+3n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098136
PNG
(5-Methylsulfanyl-4-[2-(2,4,5-trimethyl-phenylamino...)
Show SMILES CSc1sc(cc1-c1csc(Nc2cc(C)c(C)cc2C)n1)C(N)=N
Show InChI InChI=1S/C18H20N4S3/c1-9-5-11(3)13(6-10(9)2)21-18-22-14(8-24-18)12-7-15(16(19)20)25-17(12)23-4/h5-8H,1-4H3,(H3,19,20)(H,21,22)
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1.10E+3n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098135
PNG
(5-Methyl-4-[2-(3,4,5-trimethoxy-phenylamino)-thiaz...)
Show SMILES COc1cc(Nc2nc(cs2)-c2cc(sc2C)C(N)=N)cc(OC)c1OC
Show InChI InChI=1S/C18H20N4O3S2/c1-9-11(7-15(27-9)17(19)20)12-8-26-18(22-12)21-10-5-13(23-2)16(25-4)14(6-10)24-3/h5-8H,1-4H3,(H3,19,20)(H,21,22)
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1.11E+3n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
Urokinase-type plasminogen activator


(Homo sapiens (Human))
BDBM50098146
PNG
(4-[2-(Benzhydryl-amino)-thiazol-4-yl]-5-methylsulf...)
Show SMILES CSc1sc(cc1-c1csc(NC(c2ccccc2)c2ccccc2)n1)C(N)=N
Show InChI InChI=1S/C22H20N4S3/c1-27-21-16(12-18(29-21)20(23)24)17-13-28-22(25-17)26-19(14-8-4-2-5-9-14)15-10-6-3-7-11-15/h2-13,19H,1H3,(H3,23,24)(H,25,26)
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1.18E+3n/an/an/an/an/an/an/an/a



3-Dimensional Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against Urokinase-type plasminogen activator (microPa)


Bioorg Med Chem Lett 11: 915-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00102-0
BindingDB Entry DOI: 10.7270/Q2J67G5B
More data for this
Ligand-Target Pair
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