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Compile Data Set for Download or QSAR

Found 424 hits with Last Name = 'shannon' and Initial = 'he'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
GRIA2


(Homo sapiens (Human))
BDBM50207594
PNG
(2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...)
Show SMILES NS(=O)(=O)c1cccc2c1c(cc1[nH]c(=O)c(=O)[nH]c21)[N+]([O-])=O
Show InChI InChI=1S/C12H8N4O6S/c13-23(21,22)8-3-1-2-5-9(8)7(16(19)20)4-6-10(5)15-12(18)11(17)14-6/h1-4H,(H,14,17)(H,15,18)(H2,13,21,22)
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210n/an/an/an/an/an/an/an/a



Centro de Investigación Lilly

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AMPA binding to human GluR2 receptors expressed in HEK 293 cells


J Med Chem 48: 4200-3 (2005)


Article DOI: 10.1021/jm0491952
BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
More data for this
Ligand-Target Pair
GRIK1


(Homo sapiens (Human))
BDBM50168964
PNG
((3S,4aR,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenylamin...)
Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@H](CC[C@H]2CN1)Nc1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C17H22N6O2/c24-17(25)15-8-11-7-12(6-5-10(11)9-18-15)19-14-4-2-1-3-13(14)16-20-22-23-21-16/h1-4,10-12,15,18-19H,5-9H2,(H,24,25)(H,20,21,22,23)/t10-,11+,12-,15-/m0/s1
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1.55E+3n/an/an/an/an/an/an/an/a



Centro de Investigación Lilly

Curated by ChEMBL


Assay Description
Inhibition of [3H]-KA binding to iontropic glutamate receptor 5


J Med Chem 48: 4200-3 (2005)


Article DOI: 10.1021/jm0491952
BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
More data for this
Ligand-Target Pair
GRIK1


(Homo sapiens (Human))
BDBM50168965
PNG
((3S,4aS,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenoxy]-d...)
Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@H](CC[C@H]2CN1)Oc1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C17H21N5O3/c23-17(24)14-8-11-7-12(6-5-10(11)9-18-14)25-15-4-2-1-3-13(15)16-19-21-22-20-16/h1-4,10-12,14,18H,5-9H2,(H,23,24)(H,19,20,21,22)/t10-,11+,12-,14-/m0/s1
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1.69E+3n/an/an/an/an/an/an/an/a



Centro de Investigación Lilly

Curated by ChEMBL


Assay Description
Inhibition of [3H]-KA binding to iontropic glutamate receptor 5


J Med Chem 48: 4200-3 (2005)


Article DOI: 10.1021/jm0491952
BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
More data for this
Ligand-Target Pair
GRIA2


(Homo sapiens (Human))
BDBM86751
PNG
(CHEMBL14935 | LY 293558 | LY-293558)
Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@@H](CCc3nnn[nH]3)CC[C@H]2CN1
Show InChI InChI=1S/C13H21N5O2/c19-13(20)11-6-10-5-8(1-3-9(10)7-14-11)2-4-12-15-17-18-16-12/h8-11,14H,1-7H2,(H,19,20)(H,15,16,17,18)/t8-,9+,10-,11+/m1/s1
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2.21E+3n/an/an/an/an/an/an/an/a



Centro de Investigación Lilly

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AMPA binding to human Ionontropic glutamate receptor 2


J Med Chem 48: 4200-3 (2005)


Article DOI: 10.1021/jm0491952
BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
More data for this
Ligand-Target Pair
GRIK1


(Homo sapiens (Human))
BDBM86751
PNG
(CHEMBL14935 | LY 293558 | LY-293558)
Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@@H](CCc3nnn[nH]3)CC[C@H]2CN1
Show InChI InChI=1S/C13H21N5O2/c19-13(20)11-6-10-5-8(1-3-9(10)7-14-11)2-4-12-15-17-18-16-12/h8-11,14H,1-7H2,(H,19,20)(H,15,16,17,18)/t8-,9+,10-,11+/m1/s1
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4.16E+3n/an/an/an/an/an/an/an/a



Centro de Investigación Lilly

Curated by ChEMBL


Assay Description
Inhibition of [3H]-KA binding to iontropic glutamate receptor 5


J Med Chem 48: 4200-3 (2005)


Article DOI: 10.1021/jm0491952
BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
More data for this
Ligand-Target Pair
GRIA2


(Homo sapiens (Human))
BDBM50168964
PNG
((3S,4aR,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenylamin...)
Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@H](CC[C@H]2CN1)Nc1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C17H22N6O2/c24-17(25)15-8-11-7-12(6-5-10(11)9-18-15)19-14-4-2-1-3-13(14)16-20-22-23-21-16/h1-4,10-12,15,18-19H,5-9H2,(H,24,25)(H,20,21,22,23)/t10-,11+,12-,15-/m0/s1
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5.51E+3n/an/an/an/an/an/an/an/a



Centro de Investigación Lilly

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AMPA binding to human GluR2 receptors expressed in HEK 293 cells


J Med Chem 48: 4200-3 (2005)


Article DOI: 10.1021/jm0491952
BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
More data for this
Ligand-Target Pair
GRIK1


(Homo sapiens (Human))
BDBM50168963
PNG
((3S,4aS,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenoxy]-d...)
Show SMILES CC(C)COC(=O)[C@@H]1C[C@H]2C[C@H](CC[C@H]2CN1)Oc1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C21H29N5O3/c1-13(2)12-28-21(27)18-10-15-9-16(8-7-14(15)11-22-18)29-19-6-4-3-5-17(19)20-23-25-26-24-20/h3-6,13-16,18,22H,7-12H2,1-2H3,(H,23,24,25,26)/t14-,15+,16-,18-/m0/s1
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7.37E+3n/an/an/an/an/an/an/an/a



Centro de Investigación Lilly

Curated by ChEMBL


Assay Description
Inhibition of [3H]-KA binding to iontropic glutamate receptor 5


J Med Chem 48: 4200-3 (2005)


Article DOI: 10.1021/jm0491952
BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
More data for this
Ligand-Target Pair
GRIA2


(Homo sapiens (Human))
BDBM50168965
PNG
((3S,4aS,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenoxy]-d...)
Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@H](CC[C@H]2CN1)Oc1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C17H21N5O3/c23-17(24)14-8-11-7-12(6-5-10(11)9-18-14)25-15-4-2-1-3-13(15)16-19-21-22-20-16/h1-4,10-12,14,18H,5-9H2,(H,23,24)(H,19,20,21,22)/t10-,11+,12-,14-/m0/s1
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8.26E+3n/an/an/an/an/an/an/an/a



Centro de Investigación Lilly

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AMPA binding to human GluR2 receptors expressed in HEK 293 cells


J Med Chem 48: 4200-3 (2005)


Article DOI: 10.1021/jm0491952
BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
More data for this
Ligand-Target Pair
GRIK1


(Homo sapiens (Human))
BDBM50207594
PNG
(2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...)
Show SMILES NS(=O)(=O)c1cccc2c1c(cc1[nH]c(=O)c(=O)[nH]c21)[N+]([O-])=O
Show InChI InChI=1S/C12H8N4O6S/c13-23(21,22)8-3-1-2-5-9(8)7(16(19)20)4-6-10(5)15-12(18)11(17)14-6/h1-4H,(H,14,17)(H,15,18)(H2,13,21,22)
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1.17E+4n/an/an/an/an/an/an/an/a



Centro de Investigación Lilly

Curated by ChEMBL


Assay Description
Inhibition of [3H]-KA binding to iontropic glutamate receptor 5


J Med Chem 48: 4200-3 (2005)


Article DOI: 10.1021/jm0491952
BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2


(Homo sapiens (Human))
BDBM50207594
PNG
(2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...)
Show SMILES NS(=O)(=O)c1cccc2c1c(cc1[nH]c(=O)c(=O)[nH]c21)[N+]([O-])=O
Show InChI InChI=1S/C12H8N4O6S/c13-23(21,22)8-3-1-2-5-9(8)7(16(19)20)4-6-10(5)15-12(18)11(17)14-6/h1-4H,(H,14,17)(H,15,18)(H2,13,21,22)
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1.32E+4n/an/an/an/an/an/an/an/a



Centro de Investigación Lilly

Curated by ChEMBL


Assay Description
Inhibition of [3H]-KA binding to iontropic glutamate receptor 6


J Med Chem 48: 4200-3 (2005)


Article DOI: 10.1021/jm0491952
BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
More data for this
Ligand-Target Pair
GRIK1


(Homo sapiens (Human))
BDBM50168962
PNG
((3S,4aR,6S,8aR)-6-(4-Carboxy-benzyl)-decahydro-iso...)
Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@@H](Cc3ccc(cc3)C(O)=O)CC[C@H]2CN1
Show InChI InChI=1S/C18H23NO4/c20-17(21)13-4-1-11(2-5-13)7-12-3-6-14-10-19-16(18(22)23)9-15(14)8-12/h1-2,4-5,12,14-16,19H,3,6-10H2,(H,20,21)(H,22,23)/t12-,14+,15-,16+/m1/s1
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1.71E+4n/an/an/an/an/an/an/an/a



Centro de Investigación Lilly

Curated by ChEMBL


Assay Description
Inhibition of [3H]-KA binding to iontropic glutamate receptor 5


J Med Chem 48: 4200-3 (2005)


Article DOI: 10.1021/jm0491952
BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
More data for this
Ligand-Target Pair
GRIK1


(Homo sapiens (Human))
BDBM50168966
PNG
((3S,4aR,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenylamin...)
Show SMILES CCC(CC)COC(=O)[C@@H]1C[C@H]2C[C@H](CC[C@H]2CN1)Nc1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C23H34N6O2/c1-3-15(4-2)14-31-23(30)21-12-17-11-18(10-9-16(17)13-24-21)25-20-8-6-5-7-19(20)22-26-28-29-27-22/h5-8,15-18,21,24-25H,3-4,9-14H2,1-2H3,(H,26,27,28,29)/t16-,17+,18-,21-/m0/s1
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3.18E+4n/an/an/an/an/an/an/an/a



Centro de Investigación Lilly

Curated by ChEMBL


Assay Description
Inhibition of [3H]-KA binding to iontropic glutamate receptor 5


J Med Chem 48: 4200-3 (2005)


Article DOI: 10.1021/jm0491952
BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2


(Homo sapiens (Human))
BDBM86751
PNG
(CHEMBL14935 | LY 293558 | LY-293558)
Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@@H](CCc3nnn[nH]3)CC[C@H]2CN1
Show InChI InChI=1S/C13H21N5O2/c19-13(20)11-6-10-5-8(1-3-9(10)7-14-11)2-4-12-15-17-18-16-12/h8-11,14H,1-7H2,(H,19,20)(H,15,16,17,18)/t8-,9+,10-,11+/m1/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



Centro de Investigación Lilly

Curated by ChEMBL


Assay Description
Inhibition of [3H]-KA binding to iontropic glutamate receptor 6


J Med Chem 48: 4200-3 (2005)


Article DOI: 10.1021/jm0491952
BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
More data for this
Ligand-Target Pair
GRIA2


(Homo sapiens (Human))
BDBM50168966
PNG
((3S,4aR,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenylamin...)
Show SMILES CCC(CC)COC(=O)[C@@H]1C[C@H]2C[C@H](CC[C@H]2CN1)Nc1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C23H34N6O2/c1-3-15(4-2)14-31-23(30)21-12-17-11-18(10-9-16(17)13-24-21)25-20-8-6-5-7-19(20)22-26-28-29-27-22/h5-8,15-18,21,24-25H,3-4,9-14H2,1-2H3,(H,26,27,28,29)/t16-,17+,18-,21-/m0/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



Centro de Investigación Lilly

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AMPA binding to human GluR2 receptors expressed in HEK 293 cells


J Med Chem 48: 4200-3 (2005)


Article DOI: 10.1021/jm0491952
BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2


(Homo sapiens (Human))
BDBM50168966
PNG
((3S,4aR,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenylamin...)
Show SMILES CCC(CC)COC(=O)[C@@H]1C[C@H]2C[C@H](CC[C@H]2CN1)Nc1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C23H34N6O2/c1-3-15(4-2)14-31-23(30)21-12-17-11-18(10-9-16(17)13-24-21)25-20-8-6-5-7-19(20)22-26-28-29-27-22/h5-8,15-18,21,24-25H,3-4,9-14H2,1-2H3,(H,26,27,28,29)/t16-,17+,18-,21-/m0/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



Centro de Investigación Lilly

Curated by ChEMBL


Assay Description
Inhibition of [3H]-KA binding to iontropic glutamate receptor 6


J Med Chem 48: 4200-3 (2005)


Article DOI: 10.1021/jm0491952
BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
More data for this
Ligand-Target Pair
GRIA2


(Homo sapiens (Human))
BDBM50168962
PNG
((3S,4aR,6S,8aR)-6-(4-Carboxy-benzyl)-decahydro-iso...)
Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@@H](Cc3ccc(cc3)C(O)=O)CC[C@H]2CN1
Show InChI InChI=1S/C18H23NO4/c20-17(21)13-4-1-11(2-5-13)7-12-3-6-14-10-19-16(18(22)23)9-15(14)8-12/h1-2,4-5,12,14-16,19H,3,6-10H2,(H,20,21)(H,22,23)/t12-,14+,15-,16+/m1/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



Centro de Investigación Lilly

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AMPA binding to human GluR2 receptors expressed in HEK 293 cells


J Med Chem 48: 4200-3 (2005)


Article DOI: 10.1021/jm0491952
BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2


(Homo sapiens (Human))
BDBM50168962
PNG
((3S,4aR,6S,8aR)-6-(4-Carboxy-benzyl)-decahydro-iso...)
Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@@H](Cc3ccc(cc3)C(O)=O)CC[C@H]2CN1
Show InChI InChI=1S/C18H23NO4/c20-17(21)13-4-1-11(2-5-13)7-12-3-6-14-10-19-16(18(22)23)9-15(14)8-12/h1-2,4-5,12,14-16,19H,3,6-10H2,(H,20,21)(H,22,23)/t12-,14+,15-,16+/m1/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



Centro de Investigación Lilly

Curated by ChEMBL


Assay Description
Inhibition of [3H]-KA binding to iontropic glutamate receptor 6


J Med Chem 48: 4200-3 (2005)


Article DOI: 10.1021/jm0491952
BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2


(Homo sapiens (Human))
BDBM50168964
PNG
((3S,4aR,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenylamin...)
Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@H](CC[C@H]2CN1)Nc1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C17H22N6O2/c24-17(25)15-8-11-7-12(6-5-10(11)9-18-15)19-14-4-2-1-3-13(14)16-20-22-23-21-16/h1-4,10-12,15,18-19H,5-9H2,(H,24,25)(H,20,21,22,23)/t10-,11+,12-,15-/m0/s1
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>1.00E+5n/an/an/an/an/an/an/an/a



Centro de Investigación Lilly

Curated by ChEMBL


Assay Description
Inhibition of [3H]-KA binding to iontropic glutamate receptor 6


J Med Chem 48: 4200-3 (2005)


Article DOI: 10.1021/jm0491952
BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
More data for this
Ligand-Target Pair
GRIA2


(Homo sapiens (Human))
BDBM50168963
PNG
((3S,4aS,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenoxy]-d...)
Show SMILES CC(C)COC(=O)[C@@H]1C[C@H]2C[C@H](CC[C@H]2CN1)Oc1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C21H29N5O3/c1-13(2)12-28-21(27)18-10-15-9-16(8-7-14(15)11-22-18)29-19-6-4-3-5-17(19)20-23-25-26-24-20/h3-6,13-16,18,22H,7-12H2,1-2H3,(H,23,24,25,26)/t14-,15+,16-,18-/m0/s1
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Centro de Investigación Lilly

Curated by ChEMBL


Assay Description
Inhibition of [3H]-AMPA binding to human GluR2 receptors expressed in HEK 293 cells


J Med Chem 48: 4200-3 (2005)


Article DOI: 10.1021/jm0491952
BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2


(Homo sapiens (Human))
BDBM50168965
PNG
((3S,4aS,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenoxy]-d...)
Show SMILES OC(=O)[C@@H]1C[C@H]2C[C@H](CC[C@H]2CN1)Oc1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C17H21N5O3/c23-17(24)14-8-11-7-12(6-5-10(11)9-18-14)25-15-4-2-1-3-13(15)16-19-21-22-20-16/h1-4,10-12,14,18H,5-9H2,(H,23,24)(H,19,20,21,22)/t10-,11+,12-,14-/m0/s1
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Centro de Investigación Lilly

Curated by ChEMBL


Assay Description
Inhibition of [3H]-KA binding to iontropic glutamate receptor 6


J Med Chem 48: 4200-3 (2005)


Article DOI: 10.1021/jm0491952
BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, kainate 2


(Homo sapiens (Human))
BDBM50168963
PNG
((3S,4aS,6S,8aR)-6-[2-(1H-Tetrazol-5-yl)-phenoxy]-d...)
Show SMILES CC(C)COC(=O)[C@@H]1C[C@H]2C[C@H](CC[C@H]2CN1)Oc1ccccc1-c1nnn[nH]1
Show InChI InChI=1S/C21H29N5O3/c1-13(2)12-28-21(27)18-10-15-9-16(8-7-14(15)11-22-18)29-19-6-4-3-5-17(19)20-23-25-26-24-20/h3-6,13-16,18,22H,7-12H2,1-2H3,(H,23,24,25,26)/t14-,15+,16-,18-/m0/s1
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Centro de Investigación Lilly

Curated by ChEMBL


Assay Description
Inhibition of [3H]-KA binding to iontropic glutamate receptor 6


J Med Chem 48: 4200-3 (2005)


Article DOI: 10.1021/jm0491952
BindingDB Entry DOI: 10.7270/Q2HQ3ZDM
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50003355
PNG
(5-(4-Hexylsulfanyl-[1,2,5]thiadiazol-3-yl)-1-methy...)
Show SMILES CCCCCCSc1nsnc1C1=CCCN(C)C1
Show InChI InChI=1S/C14H23N3S2/c1-3-4-5-6-10-18-14-13(15-19-16-14)12-8-7-9-17(2)11-12/h8H,3-7,9-11H2,1-2H3
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Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Efficacy at muscarinic acetylcholine receptor M1 measured by the ability to inhibit the electrically stimulated twitch of the rabbit vas deferens


J Med Chem 35: 4011-9 (1992)


Article DOI: 10.1021/jm00100a005
BindingDB Entry DOI: 10.7270/Q2KW5F1K
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50003363
PNG
(1-Methyl-5-(4-pentylsulfanyl-[1,2,5]thiadiazol-3-y...)
Show SMILES CCCCCSc1nsnc1C1=CCCN(C)C1
Show InChI InChI=1S/C13H21N3S2/c1-3-4-5-9-17-13-12(14-18-15-13)11-7-6-8-16(2)10-11/h7H,3-6,8-10H2,1-2H3
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n/an/a 0.00200n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Efficacy at muscarinic acetylcholine receptor M1 measured by the ability to inhibit the electrically stimulated twitch of the rabbit vas deferens


J Med Chem 35: 4011-9 (1992)


Article DOI: 10.1021/jm00100a005
BindingDB Entry DOI: 10.7270/Q2KW5F1K
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50003366
PNG
(1-Methyl-5-(4-pentyloxy-[1,2,5]thiadiazol-3-yl)-1,...)
Show SMILES CCCCCOc1nsnc1C1=CCCN(C)C1
Show InChI InChI=1S/C13H21N3OS/c1-3-4-5-9-17-13-12(14-18-15-13)11-7-6-8-16(2)10-11/h7H,3-6,8-10H2,1-2H3
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Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Efficacy at muscarinic acetylcholine receptor M1 measured by the ability to inhibit the electrically stimulated twitch of the rabbit vas deferens


J Med Chem 35: 4011-9 (1992)


Article DOI: 10.1021/jm00100a005
BindingDB Entry DOI: 10.7270/Q2KW5F1K
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50003359
PNG
(5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2...)
Show SMILES CCCCCCOc1nsnc1C1=CCCN(C)C1
Show InChI InChI=1S/C14H23N3OS/c1-3-4-5-6-10-18-14-13(15-19-16-14)12-8-7-9-17(2)11-12/h8H,3-7,9-11H2,1-2H3
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Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Efficacy at muscarinic acetylcholine receptor M1 measured by the ability to inhibit the electrically stimulated twitch of the rabbit vas deferens


J Med Chem 35: 4011-9 (1992)


Article DOI: 10.1021/jm00100a005
BindingDB Entry DOI: 10.7270/Q2KW5F1K
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50033155
PNG
(3-(3-Butylsulfanyl-pyrazin-2-yl)-1-aza-bicyclo[2.2...)
Show SMILES CCCCSc1nccnc1C1CN2CCC1CC2
Show InChI InChI=1S/C15H23N3S/c1-2-3-10-19-15-14(16-6-7-17-15)13-11-18-8-4-12(13)5-9-18/h6-7,12-13H,2-5,8-11H2,1H3
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Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Binding activity against muscarinic acetylcholine receptor M1 in rat brain, using [3H]-Pz as the radioligand.


J Med Chem 38: 3469-81 (1995)


Article DOI: 10.1021/jm00018a007
BindingDB Entry DOI: 10.7270/Q2TB17JZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50033155
PNG
(3-(3-Butylsulfanyl-pyrazin-2-yl)-1-aza-bicyclo[2.2...)
Show SMILES CCCCSc1nccnc1C1CN2CCC1CC2
Show InChI InChI=1S/C15H23N3S/c1-2-3-10-19-15-14(16-6-7-17-15)13-11-18-8-4-12(13)5-9-18/h6-7,12-13H,2-5,8-11H2,1H3
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Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Binding activity against muscarinic acetylcholine receptor M1 in rat brain, using [3H]OXO-M as the radioligand.


J Med Chem 38: 3469-81 (1995)


Article DOI: 10.1021/jm00018a007
BindingDB Entry DOI: 10.7270/Q2TB17JZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50062577
PNG
(6-(4-Propylsulfanyl-[1,2,5]thiadiazol-3-yloxy)-1-a...)
Show SMILES CCCSc1nsnc1OC1CN2CC1CCC2
Show InChI InChI=1S/C12H19N3OS2/c1-2-6-17-12-11(13-18-14-12)16-10-8-15-5-3-4-9(10)7-15/h9-10H,2-8H2,1H3
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n/an/a 0.550n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-Pirenzepine (Pz) radioligand in rat hippocampus membranes.


J Med Chem 41: 379-92 (1998)


Article DOI: 10.1021/jm970125n
BindingDB Entry DOI: 10.7270/Q2SX6CBC
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50033162
PNG
(3-(3-Pentylsulfanyl-pyrazin-2-yl)-1-aza-bicyclo[2....)
Show SMILES CCCCCSc1nccnc1C1CN2CCC1CC2
Show InChI InChI=1S/C16H25N3S/c1-2-3-4-11-20-16-15(17-7-8-18-16)14-12-19-9-5-13(14)6-10-19/h7-8,13-14H,2-6,9-12H2,1H3
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Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Binding activity against muscarinic acetylcholine receptor M1 in rat brain, using [3H]OXO-M as the radioligand.


J Med Chem 38: 3469-81 (1995)


Article DOI: 10.1021/jm00018a007
BindingDB Entry DOI: 10.7270/Q2TB17JZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50070692
PNG
(CHEMBL99240)
Show SMILES CCCCCCOc1nsnc1[C@H]1C[N@@]2CC[C@H]1C2
Show InChI InChI=1S/C34H50N8O8/c1-3-20(2)28(42-30(46)24(12-7-8-16-35)39-29(45)23-19-22(43)14-15-27(23)44)32(48)41-26(18-21-10-5-4-6-11-21)31(47)40-25(33(49)50)13-9-17-38-34(36)37/h4-6,10-11,14-15,19-20,24-26,28,43-44H,3,7-9,12-13,16-18,35H2,1-2H3,(H,39,45)(H,40,47)(H,41,48)(H,42,46)(H,49,50)(H4,36,37,38)/t20?,24-,25-,26-,28-/m0/s1
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Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand


Bioorg Med Chem Lett 8: 2897-902 (1999)


Article DOI: 10.1016/s0960-894x(98)00509-5
BindingDB Entry DOI: 10.7270/Q27M08GK
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50072214
PNG
((R)-3-[4-(3-Phenyl-prop-2-ynyloxy)-[1,2,5]thiadiaz...)
Show SMILES C(Oc1nsnc1[C@H]1CN2CCC1C2)C#Cc1ccccc1
Show InChI InChI=1S/C17H17N3OS/c1-2-5-13(6-3-1)7-4-10-21-17-16(18-22-19-17)15-12-20-9-8-14(15)11-20/h1-3,5-6,14-15H,8-12H2/t14?,15-/m0/s1
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Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand


Bioorg Med Chem Lett 8: 2897-902 (1999)


Article DOI: 10.1016/s0960-894x(98)00509-5
BindingDB Entry DOI: 10.7270/Q27M08GK
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50033162
PNG
(3-(3-Pentylsulfanyl-pyrazin-2-yl)-1-aza-bicyclo[2....)
Show SMILES CCCCCSc1nccnc1C1CN2CCC1CC2
Show InChI InChI=1S/C16H25N3S/c1-2-3-4-11-20-16-15(17-7-8-18-16)14-12-19-9-5-13(14)6-10-19/h7-8,13-14H,2-6,9-12H2,1H3
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Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Binding activity against muscarinic acetylcholine receptor M1 in rat brain, using [3H]-Pz as the radioligand.


J Med Chem 38: 3469-81 (1995)


Article DOI: 10.1021/jm00018a007
BindingDB Entry DOI: 10.7270/Q2TB17JZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50070735
PNG
(CHEMBL317324)
Show SMILES CCCCCCOc1nsnc1[C@H]1C[N@]2C[C@@H]1CCC2
Show InChI InChI=1S/C29H48N8O8/c1-4-16(3)23(27(43)34-19(5-2)28(44)45)37-26(42)21(10-8-14-33-29(31)32)36-25(41)20(9-6-7-13-30)35-24(40)18-15-17(38)11-12-22(18)39/h11-12,15-16,19-21,23,38-39H,4-10,13-14,30H2,1-3H3,(H,34,43)(H,35,40)(H,36,41)(H,37,42)(H,44,45)(H4,31,32,33)/t16?,19?,20-,21-,23-/m0/s1
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Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand


Bioorg Med Chem Lett 8: 2897-902 (1999)


Article DOI: 10.1016/s0960-894x(98)00509-5
BindingDB Entry DOI: 10.7270/Q27M08GK
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50072227
PNG
((1R,5R,6R)-6-[4-(3-Phenyl-prop-2-ynyloxy)-[1,2,5]t...)
Show SMILES C(Oc1nsnc1[C@H]1C[N@]2C[C@@H]1CCC2)C#Cc1ccccc1
Show InChI InChI=1S/C18H19N3OS/c1-2-6-14(7-3-1)8-5-11-22-18-17(19-23-20-18)16-13-21-10-4-9-15(16)12-21/h1-3,6-7,15-16H,4,9-13H2/t15-,16-/m0/s1
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Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand


Bioorg Med Chem Lett 8: 2897-902 (1999)


Article DOI: 10.1016/s0960-894x(98)00509-5
BindingDB Entry DOI: 10.7270/Q27M08GK
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50070647
PNG
(CHEMBL329924)
Show SMILES C(CSc1nsnc1[C@H]1C[N@]2C[C@@H]1CCC2)Cc1ccccc1
Show InChI InChI=1S/C18H23N5O/c1-3-6-13-7-4-5-8-14(13)9-15(12(2)24)23-11-22-16-17(19)20-10-21-18(16)23/h4-5,7-8,10-12,15,24H,3,6,9H2,1-2H3,(H2,19,20,21)/t12-,15+/m0/s1
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Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand


Bioorg Med Chem Lett 8: 2897-902 (1999)


Article DOI: 10.1016/s0960-894x(98)00509-5
BindingDB Entry DOI: 10.7270/Q27M08GK
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50070725
PNG
(CHEMBL318403)
Show SMILES CN1CCC=C(C1)c1nsnc1SCCCc1ccccc1
Show InChI InChI=1S/C28H43N5O8/c1-4-16(3)23(26(38)30-19(5-2)28(40)41)32-25(37)21-10-8-14-33(21)27(39)20(9-6-7-13-29)31-24(36)18-15-17(34)11-12-22(18)35/h11-12,15-16,19-21,23,34-35H,4-10,13-14,29H2,1-3H3,(H,30,38)(H,31,36)(H,32,37)(H,40,41)/t16?,19?,20-,21-,23-/m0/s1
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Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand


Bioorg Med Chem Lett 8: 2897-902 (1999)


Article DOI: 10.1016/s0960-894x(98)00509-5
BindingDB Entry DOI: 10.7270/Q27M08GK
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50003351
PNG
(3-(4-butoxy-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,5,...)
Show SMILES CCCCOc1nsnc1C1=CCCN(C)C1
Show InChI InChI=1S/C12H19N3OS/c1-3-4-8-16-12-11(13-17-14-12)10-6-5-7-15(2)9-10/h6H,3-5,7-9H2,1-2H3
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Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand


Bioorg Med Chem Lett 8: 2897-902 (1999)


Article DOI: 10.1016/s0960-894x(98)00509-5
BindingDB Entry DOI: 10.7270/Q27M08GK
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50062579
PNG
(3-(4-Pentylsulfanyl-[1,2,5]thiadiazol-3-yloxy)-1-a...)
Show SMILES CCCCCSc1nsnc1OC1CN2CCC1CC2
Show InChI InChI=1S/C14H23N3OS2/c1-2-3-4-9-19-14-13(15-20-16-14)18-12-10-17-7-5-11(12)6-8-17/h11-12H,2-10H2,1H3
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Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-oxotremorine-M (Oxo-M) radioligand in rat hippocampus membranes


J Med Chem 41: 379-92 (1998)


Article DOI: 10.1021/jm970125n
BindingDB Entry DOI: 10.7270/Q2SX6CBC
More data for this
Ligand-Target Pair
Muscarinic receptor M1 and M2


(RAT)
BDBM50003351
PNG
(3-(4-butoxy-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,5,...)
Show SMILES CCCCOc1nsnc1C1=CCCN(C)C1
Show InChI InChI=1S/C12H19N3OS/c1-3-4-8-16-12-11(13-17-14-12)10-6-5-7-15(2)9-10/h6H,3-5,7-9H2,1-2H3
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Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-oxotremorine-M (Oxo-M) from rat hippocampus muscarinic acetylcholine receptor M1


J Med Chem 35: 4011-9 (1992)


Article DOI: 10.1021/jm00100a005
BindingDB Entry DOI: 10.7270/Q2KW5F1K
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50003351
PNG
(3-(4-butoxy-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,5,...)
Show SMILES CCCCOc1nsnc1C1=CCCN(C)C1
Show InChI InChI=1S/C12H19N3OS/c1-3-4-8-16-12-11(13-17-14-12)10-6-5-7-15(2)9-10/h6H,3-5,7-9H2,1-2H3
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n/an/a 1.40n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-OXO-M (oxotremorine-M) from the central muscarinic receptor sites of the rat brain membranes


Bioorg Med Chem Lett 2: 809-814 (1992)


Article DOI: 10.1016/S0960-894X(00)80536-3
BindingDB Entry DOI: 10.7270/Q2T72HBX
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50003369
PNG
(1-Methyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-1,2,...)
Show SMILES CCCOc1nsnc1C1=CCCN(C)C1
Show InChI InChI=1S/C11H17N3OS/c1-3-7-15-11-10(12-16-13-11)9-5-4-6-14(2)8-9/h5H,3-4,6-8H2,1-2H3
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n/an/a 1.60n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand


Bioorg Med Chem Lett 8: 2897-902 (1999)


Article DOI: 10.1016/s0960-894x(98)00509-5
BindingDB Entry DOI: 10.7270/Q27M08GK
More data for this
Ligand-Target Pair
Muscarinic receptor M1 and M2


(RAT)
BDBM50003369
PNG
(1-Methyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-1,2,...)
Show SMILES CCCOc1nsnc1C1=CCCN(C)C1
Show InChI InChI=1S/C11H17N3OS/c1-3-7-15-11-10(12-16-13-11)9-5-4-6-14(2)8-9/h5H,3-4,6-8H2,1-2H3
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n/an/a 1.60n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
In vitro binding affinity against rat hippocampus Muscarinic acetylcholine receptor M1 using [3H]-oxotremorine-M (Oxo-M) as radioligand


J Med Chem 35: 4011-9 (1992)


Article DOI: 10.1021/jm00100a005
BindingDB Entry DOI: 10.7270/Q2KW5F1K
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50070684
PNG
(CHEMBL321073)
Show SMILES C(CSc1nsnc1[C@H]1C[N@@]2CC[C@H]1C2)Cc1ccccc1
Show InChI InChI=1S/C28H43N7O8/c1-4-15(3)22(25(40)32-18(5-2)27(42)43)34-24(39)20-9-7-13-35(20)26(41)19(8-6-12-31-28(29)30)33-23(38)17-14-16(36)10-11-21(17)37/h10-11,14-15,18-20,22,36-37H,4-9,12-13H2,1-3H3,(H,32,40)(H,33,38)(H,34,39)(H,42,43)(H4,29,30,31)/t15?,18?,19-,20-,22-/m0/s1
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n/an/a 1.70n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand


Bioorg Med Chem Lett 8: 2897-902 (1999)


Article DOI: 10.1016/s0960-894x(98)00509-5
BindingDB Entry DOI: 10.7270/Q27M08GK
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50072225
PNG
((1R,5R,6R)-6-[4-(3-Phenyl-prop-2-ynylsulfanyl)-[1,...)
Show SMILES C(Sc1nsnc1[C@H]1C[N@]2C[C@@H]1CCC2)C#Cc1ccccc1
Show InChI InChI=1S/C18H19N3S2/c1-2-6-14(7-3-1)8-5-11-22-18-17(19-23-20-18)16-13-21-10-4-9-15(16)12-21/h1-3,6-7,15-16H,4,9-13H2/t15-,16-/m0/s1
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n/an/a 1.70n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand


Bioorg Med Chem Lett 8: 2897-902 (1999)


Article DOI: 10.1016/s0960-894x(98)00509-5
BindingDB Entry DOI: 10.7270/Q27M08GK
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50003369
PNG
(1-Methyl-5-(4-propoxy-[1,2,5]thiadiazol-3-yl)-1,2,...)
Show SMILES CCCOc1nsnc1C1=CCCN(C)C1
Show InChI InChI=1S/C11H17N3OS/c1-3-7-15-11-10(12-16-13-11)9-5-4-6-14(2)8-9/h5H,3-4,6-8H2,1-2H3
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n/an/a 2n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity towards Muscarinic acetylcholine receptor M1 by the displacement of [3H]-pirenzepine in rat cerebral cortical membranes


Bioorg Med Chem Lett 4: 2205-2210 (1994)


Article DOI: 10.1016/S0960-894X(00)80072-4
BindingDB Entry DOI: 10.7270/Q2T72HCC
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50003359
PNG
(5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2...)
Show SMILES CCCCCCOc1nsnc1C1=CCCN(C)C1
Show InChI InChI=1S/C14H23N3OS/c1-3-4-5-6-10-18-14-13(15-19-16-14)12-8-7-9-17(2)11-12/h8H,3-7,9-11H2,1-2H3
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n/an/a 2n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Binding activity against muscarinic acetylcholine receptor M1 in rat brain, using [3H]OXO-M as the radioligand.


J Med Chem 38: 3469-81 (1995)


Article DOI: 10.1021/jm00018a007
BindingDB Entry DOI: 10.7270/Q2TB17JZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50003359
PNG
(5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2...)
Show SMILES CCCCCCOc1nsnc1C1=CCCN(C)C1
Show InChI InChI=1S/C14H23N3OS/c1-3-4-5-6-10-18-14-13(15-19-16-14)12-8-7-9-17(2)11-12/h8H,3-7,9-11H2,1-2H3
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n/an/a 2n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-oxotremorine-M (Oxo-M) radioligand in rat hippocampus membranes


J Med Chem 41: 379-92 (1998)


Article DOI: 10.1021/jm970125n
BindingDB Entry DOI: 10.7270/Q2SX6CBC
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50003366
PNG
(1-Methyl-5-(4-pentyloxy-[1,2,5]thiadiazol-3-yl)-1,...)
Show SMILES CCCCCOc1nsnc1C1=CCCN(C)C1
Show InChI InChI=1S/C13H21N3OS/c1-3-4-5-9-17-13-12(14-18-15-13)11-7-6-8-16(2)10-11/h7H,3-6,8-10H2,1-2H3
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n/an/a 2n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Binding affinity against muscarinic receptor in rat brain membranes using oxotremorine-M as ligand


Bioorg Med Chem Lett 8: 2897-902 (1999)


Article DOI: 10.1016/s0960-894x(98)00509-5
BindingDB Entry DOI: 10.7270/Q27M08GK
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50033151
PNG
(3-(3-Hexylsulfanyl-pyrazin-2-yl)-1-aza-bicyclo[2.2...)
Show SMILES CCCCCCSc1nccnc1C1CN2CCC1CC2
Show InChI InChI=1S/C17H27N3S/c1-2-3-4-5-12-21-17-16(18-8-9-19-17)15-13-20-10-6-14(15)7-11-20/h8-9,14-15H,2-7,10-13H2,1H3
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n/an/a 2n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Binding activity against muscarinic acetylcholine receptor M1 in rat brain, using [3H]OXO-M as the radioligand.


J Med Chem 38: 3469-81 (1995)


Article DOI: 10.1021/jm00018a007
BindingDB Entry DOI: 10.7270/Q2TB17JZ
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM50003366
PNG
(1-Methyl-5-(4-pentyloxy-[1,2,5]thiadiazol-3-yl)-1,...)
Show SMILES CCCCCOc1nsnc1C1=CCCN(C)C1
Show InChI InChI=1S/C13H21N3OS/c1-3-4-5-9-17-13-12(14-18-15-13)11-7-6-8-16(2)10-11/h7H,3-6,8-10H2,1-2H3
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n/an/a 2n/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-pirenzepine (Pz) from rat hippocampus muscarinic acetylcholine receptor M1


J Med Chem 35: 4011-9 (1992)


Article DOI: 10.1021/jm00100a005
BindingDB Entry DOI: 10.7270/Q2KW5F1K
More data for this
Ligand-Target Pair
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