Compile Data Set for Download or QSAR
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Found 3 of ec50 for monomerid = 100205
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Wuhan University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM100205(MLS000561583 | N-[5-[2-(5-chloro-2-methoxy-anilino...)
Affinity DataEC50:  870nMAssay Description:Activity of human CFTR F508 deletion mutant expressed in FRT cells assessed as potentiation of genistein-induced iodine ion influx after 24 hrs by YF...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Wuhan University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM100205(MLS000561583 | N-[5-[2-(5-chloro-2-methoxy-anilino...)
Affinity DataEC50:  700nMAssay Description:Binding affinity to human CFTR F508 deletion mutant expressed in FRT cells assessed as increase in iodine influx after 16 to 20 hrs by fluorescence a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Wuhan University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM100205(MLS000561583 | N-[5-[2-(5-chloro-2-methoxy-anilino...)
Affinity DataEC50:  708nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed