Compile Data Set for Download or QSAR
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Found 3 of ic50 for monomerid = 10304
TargetSecreted chorismate mutase(Mycobacterium tuberculosis H37Rv)
Birla Institute Of Technology

LigandPNGBDBM10304(1-methyl-2,3-dihydro-1H-indole-2,3-dione | CHEMBL6...)
Affinity DataIC50:  1.96E+3nMT: 2°CAssay Description:The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...More data for this Ligand-Target Pair
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TargetTransthyretin(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM10304(1-methyl-2,3-dihydro-1H-indole-2,3-dione | CHEMBL6...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of TTR mediated fibrillogenesis assessed as acid-induced protein aggregation turbidity after 1.5 hrs by turbidimetric assayMore data for this Ligand-Target Pair
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TargetCaspase-3(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM10304(1-methyl-2,3-dihydro-1H-indole-2,3-dione | CHEMBL6...)
Affinity DataIC50: >5.00E+4nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC/AFC are processed by caspases with or without inhibitors, and the accumulation of AMC/AFC was assessed with...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed