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Found 11 of ic50 for monomerid = 10441
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute Of Science

LigandPNGBDBM10441((+)-Huperzine A | (+/-)Huperzine A | (-)-Huperzine...)
Affinity DataKi:  47.1nM ΔG°:  -9.89kcal/mole IC50:  114nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Weizmann Institute Of Science

LigandPNGBDBM10441((+)-Huperzine A | (+/-)Huperzine A | (-)-Huperzine...)
Affinity DataKi:  175nM ΔG°:  -9.12kcal/mole IC50:  414nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institutes Of Health

LigandPNGBDBM10441((+)-Huperzine A | (+/-)Huperzine A | (-)-Huperzine...)
Affinity DataIC50:  47nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institutes Of Health

LigandPNGBDBM10441((+)-Huperzine A | (+/-)Huperzine A | (-)-Huperzine...)
Affinity DataIC50:  47nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Weizmann Institute Of Science

LigandPNGBDBM10441((+)-Huperzine A | (+/-)Huperzine A | (-)-Huperzine...)
Affinity DataIC50:  72.4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institutes Of Health

LigandPNGBDBM10441((+)-Huperzine A | (+/-)Huperzine A | (-)-Huperzine...)
Affinity DataIC50:  260nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
National Institutes Of Health

LigandPNGBDBM10441((+)-Huperzine A | (+/-)Huperzine A | (-)-Huperzine...)
Affinity DataIC50:  648nMpH: 8.0Assay Description:The reaction mixture was consisted of 100 µL of the total volume. To the solution of PBS (pH 8.0, 30 µL) consisted of KH2PO4 and K2HPO4 in 96-well pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Universitat De Barcelona

LigandPNGBDBM10441((+)-Huperzine A | (+/-)Huperzine A | (-)-Huperzine...)
Affinity DataIC50: >1.00E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Universitat De Barcelona

LigandPNGBDBM10441((+)-Huperzine A | (+/-)Huperzine A | (-)-Huperzine...)
Affinity DataIC50: >1.00E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Universitat De Barcelona

LigandPNGBDBM10441((+)-Huperzine A | (+/-)Huperzine A | (-)-Huperzine...)
Affinity DataIC50: >1.00E+4nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Shanghai Institute Of Materia Medica

LigandPNGBDBM10441((+)-Huperzine A | (+/-)Huperzine A | (-)-Huperzine...)
Affinity DataIC50:  7.02E+4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed