Compile Data Set for Download or QSAR
maximum 50k data
Found 9 of ic50 for monomerid = 121390
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM121390(US8722890, 5)
Affinity DataIC50:  1.22nMpH: 7.1 T: 2°CAssay Description:To determine the activity of the various kinases, a homogenous time-resolved fluorescence (HTRF) in vitro kinase assay was used. (Mathis, G., HTRF(R)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM121390(US8722890, 5)
Affinity DataIC50:  1.34nMpH: 7.1 T: 2°CAssay Description:To determine the activity of the various kinases, a homogenous time-resolved fluorescence (HTRF) in vitro kinase assay was used. (Mathis, G., HTRF(R)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM121390(US8722890, 5)
Affinity DataIC50:  1.45nMpH: 7.1 T: 2°CAssay Description:To determine the activity of the various kinases, a homogenous time-resolved fluorescence (HTRF) in vitro kinase assay was used. (Mathis, G., HTRF(R)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM121390(US8722890, 5)
Affinity DataIC50:  1.83nMpH: 7.1 T: 2°CAssay Description:To determine the activity of the various kinases, a homogenous time-resolved fluorescence (HTRF) in vitro kinase assay was used. (Mathis, G., HTRF(R)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM121390(US8722890, 5)
Affinity DataIC50:  12.6nMpH: 7.1 T: 2°CAssay Description:To determine the activity of the various kinases, a homogenous time-resolved fluorescence (HTRF) in vitro kinase assay was used. (Mathis, G., HTRF(R)...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase B(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM121390(US8722890, 5)
Affinity DataIC50:  28.9nMpH: 7.4Assay Description:To determine Aurora B activity of representative compounds of the invention, Active Aurora B enzyme (recombinant residues 1-344) and INCENP (recombin...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAurora kinase A(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM121390(US8722890, 5)
Affinity DataIC50:  570nMpH: 7.4Assay Description:To determine Aurora A and C activity of representative compounds of the invention, Active Aurora A or C enzyme was incubated in wells of a 384 well p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM121390(US8722890, 5)
Affinity DataIC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:Assays (200 μL final volume) were carried out in NUNC polypropylene deep well plates in 50 mM potassium phosphate buffer, pH 7.4, using a microt...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM121390(US8722890, 5)
Affinity DataIC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:Assays (200 μL final volume) were carried out in NUNC polypropylene deep well plates in 50 mM potassium phosphate buffer, pH 7.4, using a microt...More data for this Ligand-Target Pair
In DepthDetails US Patent