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Found 18 of ic50 for monomerid = 127677
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Array Biopharm

US Patent
LigandPNGBDBM127677(US10251889, Example 51 | US10758542, Example 51 | ...)
Affinity DataIC50:  1.18nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Jak2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM127677(US10251889, Example 51 | US10758542, Example 51 | ...)
Affinity DataIC50:  1.18nMAssay Description:An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM127677(US10251889, Example 51 | US10758542, Example 51 | ...)
Affinity DataIC50:  1.18nMAssay Description:Trk enzymatic selectivity was assessed using Omnia™ Kinase Assay reagents from Invitrogen Corp. Enzyme (either TrkA or TrkB from Invitrogen Corp.) an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM127677(US10251889, Example 51 | US10758542, Example 51 | ...)
Affinity DataIC50:  1.18nMAssay Description:An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM127677(US10251889, Example 51 | US10758542, Example 51 | ...)
Affinity DataIC50:  1.23nMAssay Description:An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM127677(US10251889, Example 51 | US10758542, Example 51 | ...)
Affinity DataIC50:  1.23nMAssay Description:Trk enzymatic selectivity was assessed using Omnia™ Kinase Assay reagents from Invitrogen Corp. Enzyme (either TrkA or TrkB from Invitrogen Corp.) an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM127677(US10251889, Example 51 | US10758542, Example 51 | ...)
Affinity DataIC50:  1.23nMAssay Description:An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM127677(US10251889, Example 51 | US10758542, Example 51 | ...)
Affinity DataIC50:  1.23nMpH: 7.5Assay Description:An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Array Biopharm

US Patent
LigandPNGBDBM127677(US10251889, Example 51 | US10758542, Example 51 | ...)
Affinity DataIC50:  1.23nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Jak2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM127677(US10251889, Example 51 | US10758542, Example 51 | ...)
Affinity DataIC50:  186nMAssay Description:An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 [808-1132](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM127677(US10251889, Example 51 | US10758542, Example 51 | ...)
Affinity DataIC50:  186nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Jak2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 [808-1132](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM127677(US10251889, Example 51 | US10758542, Example 51 | ...)
Affinity DataIC50:  186nMAssay Description:Jak2: Compounds of Formula I were screened for their ability to inhibit Jak2 using the general enzyme inhibition assay method, in which the assay mix...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Array Biopharm

US Patent
LigandPNGBDBM127677(US10251889, Example 51 | US10758542, Example 51 | ...)
Affinity DataIC50:  186nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Jak2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM127677(US10251889, Example 51 | US10758542, Example 51 | ...)
Affinity DataIC50:  418nMAssay Description:An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Array Biopharm

US Patent
LigandPNGBDBM127677(US10251889, Example 51 | US10758542, Example 51 | ...)
Affinity DataIC50:  418nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Jak2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 [808-1132](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM127677(US10251889, Example 51 | US10758542, Example 51 | ...)
Affinity DataIC50:  418nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Jak2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2 [808-1132](Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM127677(US10251889, Example 51 | US10758542, Example 51 | ...)
Affinity DataIC50:  418nMAssay Description:Jak2: Compounds of Formula I were screened for their ability to inhibit Jak2 using the general enzyme inhibition assay method, in which the assay mix...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Array Biopharm

US Patent
LigandPNGBDBM127677(US10251889, Example 51 | US10758542, Example 51 | ...)
Affinity DataIC50:  418nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Jak2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
In DepthDetails US Patent