Found 20 of ic50 for monomerid = 13934 
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of wild-type HIV1 protease expressed in Escherichia coli assessed as reduction in product formation preincubated for 30 mins followed by a...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 0.0400nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli using Val-Ser-Gln-Asn-(beta-naphtyl)Ala-Pro-Ile-Val as substrate preincubated for 30 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 subtype C protease expressed in Escherichia coli BL21 assessed as hydrolysis of substrate using chromogenic substrate Lys-Ala-Arg-...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 subtype C protease Q7K mutant expressed in Escherichia coli BL21 (DE3) pLysS using Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-Ala-Nle-NH2...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of South African HIV1 subtype C protease expressed in Escherichia coli BL21S4 (DE3)pLysS cells using Lys-Ala-Arg-Val-Nle-p-nitro-Phe-Glu-A...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of wild type C-South African Human immunodeficiency virus 1 protease using chromogenic peptide H-1048 as substrate by UV spectrophotometri...More data for this Ligand-Target Pair
Affinity DataIC50: 6.92nMAssay Description:Protease inhibitors (PI) are used to treat HIV infection by preventing viral assembly and maturation through the inhibition of HIV-1 protease activit...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:The percent reduction of the reverse transcriptase (RT) activity in HIV-1/MN-infected MT-2 cells.More data for this Ligand-Target Pair
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Centre
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Centre
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant UGT1A1 using bilirubin as substrate incubated for 40 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Centre
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Centre
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human UGT1A1 using bilirubin as substrate preincubated for 5 mins followed by substrate addition and measured after 40 mins...More data for this Ligand-Target Pair
TargetSolute carrier organic anion transporter family member 1B3(Homo sapiens (Human))
Uppsala University
Curated by ChEMBL
Uppsala University
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of human liver OATP1B3 expressed in HEK293 Flp-In cells assessed as reduction in [3H]E17-betaG uptake incubated for 5 mins by scintillatio...More data for this Ligand-Target Pair
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Centre
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Centre
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of UGT1A1 in human liver microsomes using beta-estradiol as substrate incubated for 40 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Biocon-Bristol Myers Squibb Research And Development Centre
Curated by ChEMBL
Biocon-Bristol Myers Squibb Research And Development Centre
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of UGT1A1 in human liver microsomes using beta-estradiol as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
TargetSolute carrier organic anion transporter family member 1B1(Homo sapiens (Human))
Uppsala University
Curated by ChEMBL
Uppsala University
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human liver OATP1B1 expressed in HEK293 Flp-In cells assessed as reduction in E17-betaG uptake by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of UGT1A1 in rat liver microsomes using beta-estradiol as substrate preincubated for 5 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of recombinant rat UGT1A1 using beta-estradiol as substrate preincubated for 5 mins followed by substrate addition and measured after 40 m...More data for this Ligand-Target Pair
TargetSolute carrier organic anion transporter family member 2B1(Homo sapiens (Human))
Uppsala University
Curated by ChEMBL
Uppsala University
Curated by ChEMBL
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human liver OATP2B1 expressed in HEK293 Flp-In cells assessed as reduction in [3H]E3S uptake incubated for 5 mins by scintillation coun...More data for this Ligand-Target Pair
Affinity DataIC50: 6.78E+4nMAssay Description:Inhibition of human MDR1-dependent accumulation of calcein-AM expressed in MDCK2 cellsMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Federal University Of Parana
Curated by ChEMBL
Federal University Of Parana
Curated by ChEMBL
Affinity DataIC50: 6.91E+4nMAssay Description:Inhibition of human ABCG2 expressed in dog MDCK-II-BCRP cells mediated pheophorbide A efflux preincubated with PhA followed by compound addition and ...More data for this Ligand-Target Pair
