Affinity DataIC50: 24nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:The inhibitory activities of the compound of the invention against c-Src and Syk enzymes (Invitrogen) are evaluated in a similar fashion to that desc...More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
Affinity DataIC50: 224nMAssay Description:The inhibitory activities of compounds of the invention against p38MAPKγ (MAPK12: Invitrogen) are evaluated in a similar fashion to that describ...More data for this Ligand-Target Pair
Affinity DataIC50: 224nMAssay Description:The following two assay variants can be used for determination of p38 MAPKα inhibition.Method 1The inhibitory activities of test compounds again...More data for this Ligand-Target Pair
Affinity DataIC50: 224nMAssay Description:Method 2: This method follows the same steps as Method 1 above, but utilises a higher concentration of the p38 MAPKα protein (2.5 uL of 200 ng/...More data for this Ligand-Target Pair
Affinity DataIC50: 411nMAssay Description:Method 1: The inhibitory activities of the compound of the invention against the GSK 3alpha enzyme isoform (Invitrogen), are evaluated by determining...More data for this Ligand-Target Pair
Affinity DataIC50: 411nMAssay Description:Method 2: This method follows the same steps as Method 1 above, but utilises a shorter period of mixing of the test compound (105 minutes instead of ...More data for this Ligand-Target Pair
Affinity DataIC50: 411nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
Affinity DataIC50: 591nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
Affinity DataIC50: 591nMAssay Description:The inhibitory activities of the compound of the invention against c-Src and Syk enzymes (Invitrogen) are evaluated in a similar fashion to that desc...More data for this Ligand-Target Pair
Affinity DataIC50: 591nMAssay Description:The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:Compounds of the invention were tested for inhibition of the human ether a go-go (hERG) channel using IonWorks patch clamp electrophysiology at Essen...More data for this Ligand-Target Pair
Affinity DataIC50: 7.80E+3nMAssay Description:Summary of CYP3A4 inhibition studies for various Compound Examples using 30 min preincubation.More data for this Ligand-Target Pair
Affinity DataIC50: >1.50E+4nMAssay Description:Summary of CYP2C9 inhibition studies for various Compound Examples using 0 min preincubation.More data for this Ligand-Target Pair
Affinity DataIC50: >1.50E+4nMAssay Description:Summary of CYP3A4 inhibition studies for various Compound Examples using 0 min preincubation.More data for this Ligand-Target Pair
Affinity DataIC50: >1.50E+4nMAssay Description:Summary of CYP2C9 inhibition studies for various Compound Examples using 30 min preincubation.More data for this Ligand-Target Pair