Compile Data Set for Download or QSAR
maximum 50k data
Found 14 of ic50 for monomerid = 149770
TargetBeta-secretase 1(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149770(US8975415, RP51a | US8975415, RP51b | US8975415, R...)
Affinity DataKi:  137nM ΔG°:  -9.36kcal/mole IC50:  172nMpH: 4.4 T: 2°CAssay Description:Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149770(US8975415, RP51a | US8975415, RP51b | US8975415, R...)
Affinity DataKi:  137nM IC50:  172nMAssay Description:Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149770(US8975415, RP51a | US8975415, RP51b | US8975415, R...)
Affinity DataIC50:  40nMT: 2°CAssay Description:Test Example 3: The potency of compounds against BACE1 activity was determined in a cellular assay of Aβ production. Human SK-N-BE(2) neuroblas...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149770(US8975415, RP51a | US8975415, RP51b | US8975415, R...)
Affinity DataIC50:  72nMT: 2°CAssay Description:Test Example 3: The potency of compounds against BACE1 activity was determined in a cellular assay of Aβ production. Human SK-N-BE(2) neuroblas...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149770(US8975415, RP51a | US8975415, RP51b | US8975415, R...)
Affinity DataIC50:  397nMpH: 4.4 T: 2°CAssay Description:Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149770(US8975415, RP51a | US8975415, RP51b | US8975415, R...)
Affinity DataIC50:  397nMAssay Description:Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149770(US8975415, RP51a | US8975415, RP51b | US8975415, R...)
Affinity DataIC50: >1.00E+4nMAssay Description:Test Example 5: The hERG potassium current was measured in a hERG-stably-expressing Chinese hamster ovary K1 (CHO) cells. The experiments were perfor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149770(US8975415, RP51a | US8975415, RP51b | US8975415, R...)
Affinity DataIC50: >1.00E+4nMAssay Description:Test Example 5: The hERG potassium current was measured in a hERG-stably-expressing Chinese hamster ovary K1 (CHO) cells. The experiments were perfor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149770(US8975415, RP51a | US8975415, RP51b | US8975415, R...)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The hERG potassium current was measured in a hERG-stably-expressing Chinese hamster ovary K1 (CHO) cells. The experiments were performed using an aut...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149770(US8975415, RP51a | US8975415, RP51b | US8975415, R...)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The hERG potassium current was measured in a hERG-stably-expressing Chinese hamster ovary K1 (CHO) cells. The experiments were performed using an aut...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149770(US8975415, RP51a | US8975415, RP51b | US8975415, R...)
Affinity DataIC50: >1.00E+4nMAssay Description:Test Example 5: The hERG potassium current was measured in a hERG-stably-expressing Chinese hamster ovary K1 (CHO) cells. The experiments were perfor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149770(US8975415, RP51a | US8975415, RP51b | US8975415, R...)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The hERG potassium current was measured in a hERG-stably-expressing Chinese hamster ovary K1 (CHO) cells. The experiments were performed using an aut...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149770(US8975415, RP51a | US8975415, RP51b | US8975415, R...)
Affinity DataIC50:  4.86E+4nMAssay Description:Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experiments were perfo...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Comentis

US Patent
LigandPNGBDBM149770(US8975415, RP51a | US8975415, RP51b | US8975415, R...)
Affinity DataIC50:  4.86E+4nMpH: 4.4 T: 2°CAssay Description:Test Example 1: Potency of test compounds were determined by measurement of their inhibition of BACE1 activity toward a fluorescent substrate. Experi...More data for this Ligand-Target Pair
In DepthDetails US Patent