Compile Data Set for Download or QSAR
maximum 50k data
Found 12 of ic50 for monomerid = 152692
TargetHistone deacetylase 6(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite

Curated by ChEMBL
LigandPNGBDBM152692(Thiol-SAHA (t-SAHA))
Affinity DataIC50:  19nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM152692(Thiol-SAHA (t-SAHA))
Affinity DataIC50:  58nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite

Curated by ChEMBL
LigandPNGBDBM152692(Thiol-SAHA (t-SAHA))
Affinity DataIC50:  74nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite

Curated by ChEMBL
LigandPNGBDBM152692(Thiol-SAHA (t-SAHA))
Affinity DataIC50:  201nMAssay Description:Inhibition of HDAC3 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM152692(Thiol-SAHA (t-SAHA))
Affinity DataIC50:  210nMAssay Description:Inhibitory concentration against human histone deacetylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM152692(Thiol-SAHA (t-SAHA))
Affinity DataIC50:  210nMAssay Description:In vitro inhibitory activity against human histone deacetylase (HDAC) using HeLa nuclear extractMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM152692(Thiol-SAHA (t-SAHA))
Affinity DataIC50:  218nMAssay Description:Inhibition of recombinant human HDAC1 using Boc-Lys(Ac)-AMC as substrate preincubated for 15 mins followed by substrate addition measured after 60 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite

Curated by ChEMBL
LigandPNGBDBM152692(Thiol-SAHA (t-SAHA))
Affinity DataIC50:  262nMAssay Description:Inhibition of HDAC11 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite

Curated by ChEMBL
LigandPNGBDBM152692(Thiol-SAHA (t-SAHA))
Affinity DataIC50:  270nMAssay Description:Inhibition of HDAC10 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM152692(Thiol-SAHA (t-SAHA))
Affinity DataIC50:  288nMAssay Description:Inhibition of HDAC1 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite

Curated by ChEMBL
LigandPNGBDBM152692(Thiol-SAHA (t-SAHA))
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorogenic tetrapeptide RHK(Ac)K(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
R&D Sigma-Tau Industrie Farmaceutiche Riunite

Curated by ChEMBL
LigandPNGBDBM152692(Thiol-SAHA (t-SAHA))
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of HDAC2 (unknown origin) using fluorogenic tetrapeptide RHKK(Ac) substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed