Affinity DataIC50: >10nMAssay Description:Inhibition of p56 Lck kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of PKC-beta2 kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition against Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
Affinity DataIC50: >20nMAssay Description:Inhibition of JNK 2 beta2 kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:The IC50s were determined by incubating each test compound with activated p38-alpha in a 96-well plate that had been pre-treated with ATF-2-GST to al...More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: >50nMAssay Description:Inhibition of ERK2 kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: >50nMAssay Description:Inhibition of JNK1 kinaseMore data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: >50nMAssay Description:Inhibition of cRaf kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of PKCalpha kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: >100nMAssay Description:Inhibition of cdc2 kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of p38alpha phosphorylation in IL1alpha-stimulated HLF cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of HSP27 phosphorylation in IL1alpha-stimulated HLF cellsMore data for this Ligand-Target Pair