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Found 14 of ic50 for monomerid = 180052
TargetMonoglyceride lipase(Homo sapiens (Human))
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM180052(US9133148, 9aq)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of MGLL in human intact PC3 cells preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM180052(US9133148, 9aq)
Affinity DataIC50:  14nMAssay Description:Inhibition of MGLL derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM180052(US9133148, 9aq)
Affinity DataIC50:  27nMAssay Description:Inhibition of MGLL derived from mouse brain homogenates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM180052(US9133148, 9aq)
Affinity DataIC50:  253nMAssay Description:Inhibition of ABHD6 in human intact PC3 cells preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM180052(US9133148, 9aq)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of ABHD6 derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM180052(US9133148, 9aq)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of recombinant human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM180052(US9133148, 9aq)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PLA2G7 derived from human PC3 cell lysates preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
The Scripps Research Institute

US Patent
LigandPNGBDBM180052(US9133148, 9aq)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:Proteomes (mouse brain membrane fraction or cell lysates) (50 uL, 1.0 mg/mL total protein concentration) were preincubated with varying concentration...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM180052(US9133148, 9aq)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM180052(US9133148, 9aq)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A5(Homo sapiens (Human))
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM180052(US9133148, 9aq)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human CYP3A5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM180052(US9133148, 9aq)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM180052(US9133148, 9aq)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Abide Therapeutics

Curated by ChEMBL
LigandPNGBDBM180052(US9133148, 9aq)
Affinity DataIC50:  4.94E+5nMAssay Description:Inhibition of PLA2G7 in human intact PC3 cells preincubated for 30 mins followed by JW912 addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed