Affinity DataKd: <1nMAssay Description:Inhibitory activity against dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataKd: 3.20nMpH: 6.0Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 2.30nMpH: 6.0Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 1.10E+3nMpH: 9.5Assay Description:Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 6More data for this Ligand-Target Pair
Affinity DataKd: 84nMpH: 8.0Assay Description:Dissociation constant(Koff) at Phe-31 of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKd: 0.0960nMpH: 8.0Assay Description:Association constant(Kon) at Tyr-31 of dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
Affinity DataKd: 1.70E+3nMpH: 9.5Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 31nMpH: 9.5Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
Affinity DataKd: 0.0230nMpH: 6.0Assay Description:Thermodynamic Dissociation Constant for compound-Tyr31-dihydrofolate reductase (DHFR) complex at pH 6More data for this Ligand-Target Pair
Affinity DataKd: 140nMpH: 8.0Assay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair