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Found 12 of ec50 for drug = Ambisome
TargetAdenosine receptor A1(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM18137(AMP | CHEMBL752 | US11185100, TABLE 7.3 | [(2R,3S,...)
Affinity DataEC50:  500nMAssay Description:Agonist activity at human A1AR expressed in HEK293T/17 cells assessed as inhibition of isoproterenol-induced cAMP accumulation incubated for 10 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-2/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Nanjing University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM18137(AMP | CHEMBL752 | US11185100, TABLE 7.3 | [(2R,3S,...)
Affinity DataEC50:  1.40E+3nMAssay Description:Inhibition of protein kinase C epsilon expressed in Sf-9 cellsMore data for this Ligand-Target Pair
LigandPNGBDBM18137(AMP | CHEMBL752 | US11185100, TABLE 7.3 | [(2R,3S,...)
Affinity DataEC50:  1.52E+3nMAssay Description:Activation of recombinant human AMPK alpha1/beta1/gamma1 using Cy5-labelled SAMS as substrate assessed as protection from Thr172 residue dephosphoryl...More data for this Ligand-Target Pair
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM18137(AMP | CHEMBL752 | US11185100, TABLE 7.3 | [(2R,3S,...)
Affinity DataEC50:  3.50E+3nMAssay Description:Measure of Agonist Potency at turkey Purinoceptor P2Y1 stably expressed in 131N1 astrocytoma cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Meleagris gallopavo)
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM18137(AMP | CHEMBL752 | US11185100, TABLE 7.3 | [(2R,3S,...)
Affinity DataEC50:  3.50E+3nMAssay Description:Measure of Agonist Potency at turkey Purinoceptor P2Y1 stably expressed in 131N1 astrocytoma cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM18137(AMP | CHEMBL752 | US11185100, TABLE 7.3 | [(2R,3S,...)
Affinity DataEC50:  3.70E+3nMAssay Description:Measure of Agonist Potency at human P2Y purinoceptor 2 (hP2Y2) stably expressed in 131N1 astrocytoma cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM18137(AMP | CHEMBL752 | US11185100, TABLE 7.3 | [(2R,3S,...)
Affinity DataEC50:  3.70E+3nMAssay Description:Measure of Agonist Potency at human P2Y purinoceptor 2 (hP2Y2) stably expressed in 131N1 astrocytoma cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM18137(AMP | CHEMBL752 | US11185100, TABLE 7.3 | [(2R,3S,...)
Affinity DataEC50:  7.20E+3nMAssay Description:Measure of Agonist Potency at human P2Y purinoceptor 1 (hP2Y1) stably expressed in 131N1 astrocytoma cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 1(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM18137(AMP | CHEMBL752 | US11185100, TABLE 7.3 | [(2R,3S,...)
Affinity DataEC50:  7.20E+3nMAssay Description:Measure of Agonist Potency at human P2Y purinoceptor 1 (hP2Y1) stably expressed in 131N1 astrocytoma cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTaste receptor type 1 member 1/3(Homo sapiens (Human))
Mars

US Patent
LigandPNGBDBM18137(AMP | CHEMBL752 | US11185100, TABLE 7.3 | [(2R,3S,...)
Affinity DataEC50:  1.10E+4nMAssay Description:The concentration of alanine is 20 mM.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetP2Y purinoceptor 11(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM18137(AMP | CHEMBL752 | US11185100, TABLE 7.3 | [(2R,3S,...)
Affinity DataEC50:  1.73E+4nMAssay Description:Measure of Agonist Potency at human P2Y purinoceptor 11 (hP2Y11) stably expressed in 131N1 astrocytoma cell at 10 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM18137(AMP | CHEMBL752 | US11185100, TABLE 7.3 | [(2R,3S,...)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay