Affinity DataKi: 1.30nMAssay Description:NET: This protocol was designed to measure inhibition of uptake by the human norepinephrine transporter. The reagents were human NET (HEK293F) cells,...More data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Invitro competitive binding versus [3H]-citalopram in murine kidney cells transfected with cDNA for human serotonin transporter (SERT)More data for this Ligand-Target Pair
TargetTransporter(Rattus norvegicus)
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]-nisoxetine from NET in Sprague-Dawley rat brain prefrontal cortex incubated for 180 mins by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Binding affinity for Norepinephrine transporter (NET) expressed in LCK PK1 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 6nM ΔG°: -11.7kcal/molepH: 7.4 T: 2°CAssay Description:Compounds were evaluated the inhibition of [3H] nisoxetine binding to MDCK-Net6 cells, stably transfected with the human norepinephrine transporter (...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(BOVINE)
The University Of Queensland
Curated by PDSP Ki Database
The University Of Queensland
Curated by PDSP Ki Database
TargetTransporter(Rattus norvegicus)
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
National Institutes Of Drug Abuse - Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 9.90nMAssay Description:Binding affinity against norepinephrine transporter (NET) by displacement of [3H]nisoxetine in male wistar ratsMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Invitro competitive binding versus [N-methyl-3H]-WIN 35428 in murine kidney cells transfected with cDNA for human dopamine transporter (DAT)More data for this Ligand-Target Pair
Affinity DataKi: 54.4nMAssay Description:SERT: This protocol was designed to measure inhibition of uptake by the human serotonin transporter. The reagents were human SERT (HEK293F) cells, fl...More data for this Ligand-Target Pair
Affinity DataKi: 82.5nMAssay Description:DAT: This protocol was designed to measure inhibition of uptake by the human dopamine transporter. The reagents were human DAT (HEK293F) cells, GBR 1...More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Harvard University
Curated by PDSP Ki Database
Harvard University
Curated by PDSP Ki Database
Affinity DataKi: 203nMAssay Description:Binding affinity for serotonin transporter expresed in LCK PK1 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Harvard University
Curated by PDSP Ki Database
Harvard University
Curated by PDSP Ki Database
Affinity DataKi: 277nMAssay Description:Displacement of [3H]citalopram from SERT in Sprague-dawley rat frontal cortex by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Harvard University
Curated by PDSP Ki Database
Harvard University
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Lundbeck Ais
Curated by PDSP Ki Database
Lundbeck Ais
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Harvard University
Curated by PDSP Ki Database
Harvard University
Curated by PDSP Ki Database
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity for dopamine transporter expressed in LCK PK1 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Harvard University
Curated by PDSP Ki Database
Harvard University
Curated by PDSP Ki Database
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Wake Forest University
Curated by PDSP Ki Database
Wake Forest University
Curated by PDSP Ki Database
TargetSodium-dependent noradrenaline transporter(MOUSE)
National Institutes Of Health
Curated by PDSP Ki Database
National Institutes Of Health
Curated by PDSP Ki Database