Compile Data Set for Download or QSAR
maximum 50k data
Found 10 of ic50 for monomerid = 22774
TargetCaspase-1(Homo sapiens (Human))
RhóNe-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM22774(1,4-Benzoquinone | Benzil-related compound, 53 | C...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibitory activity of the compound against IL-1 beta converting enzyme was evaluated.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM22774(1,4-Benzoquinone | Benzil-related compound, 53 | C...)
Affinity DataIC50:  4.82E+3nMAssay Description:Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cell microsomes using kynuramine as substrate after 20 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Schistosoma mansoni)
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM22774(1,4-Benzoquinone | Benzil-related compound, 53 | C...)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of Schistosoma mansoni DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM22774(1,4-Benzoquinone | Benzil-related compound, 53 | C...)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect cell microsomes using kynuramine as substrate after 20 mins by flu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM22774(1,4-Benzoquinone | Benzil-related compound, 53 | C...)
Affinity DataIC50:  1.39E+4nMAssay Description:Inhibition of biotin-labelled p53 binding to MDM2 (25 to 109 residues) (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Universidade De S£O Paulo

Curated by ChEMBL
LigandPNGBDBM22774(1,4-Benzoquinone | Benzil-related compound, 53 | C...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of human DHODH using DHO as substrate measured at 4 secs interval for 60 secs by DCIP reduction based indirect assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA dC->dU-editing enzyme APOBEC-3G(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM22774(1,4-Benzoquinone | Benzil-related compound, 53 | C...)
Affinity DataIC50:  3.61E+4nMT: 2°CAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetDual specificity protein phosphatase 1(Mus musculus)
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM22774(1,4-Benzoquinone | Benzil-related compound, 53 | C...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of histidine-tagged mouse MKP1 catalytic domain expressed in human Hela cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetM-phase inducer phosphatase 2(Homo sapiens (Human))
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM22774(1,4-Benzoquinone | Benzil-related compound, 53 | C...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of histidine-tagged human recombinant Cdc25B catalytic domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 6(Rattus norvegicus)
Virginia Polytechnic Institute And State University

Curated by ChEMBL
LigandPNGBDBM22774(1,4-Benzoquinone | Benzil-related compound, 53 | C...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of histidine-tagged rat recombinant MKP3 catalytic domain expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed