Compile Data Set for Download or QSAR
maximum 50k data
Found 6 of ki for monomerid = 23772
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institut De Biologie Structurale

LigandPNGBDBM23772((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...)
Affinity DataKi:  50nM ΔG°:  -9.85kcal/molepH: 6.9 T: 2°CAssay Description:The microtubule-activated ATPase rates were measured using the pyruvate kinase/lactate dehydrogenase-linked assay. To optimize the signal for basal E...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institut De Biologie Structurale

LigandPNGBDBM23772((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...)
Affinity DataKi:  71.9nMAssay Description:Inhibition of C-terminal His6-tagged human Eg5 basal ATPase activityMore data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institut De Biologie Structurale

LigandPNGBDBM23772((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...)
Affinity DataKi:  107nMAssay Description:Inhibition of human N-terminal His6-tagged Eg5 (1 to 368 amino acid residues) motor domain basal ATPase activity expressed in Escherichia coli BL21 (...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institut De Biologie Structurale

LigandPNGBDBM23772((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...)
Affinity DataKi:  129nMAssay Description:Inhibition of MT-stimulated human N-terminal His6-tagged Eg5 (1 to 368 amino acid residues) motor domain ATPase activity expressed in Escherichia col...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institut De Biologie Structurale

LigandPNGBDBM23772((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...)
Affinity DataKi:  136nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...More data for this Ligand-Target Pair
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Institut De Biologie Structurale

LigandPNGBDBM23772((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...)
Affinity DataKi:  144nMAssay Description:Inhibition of N-terminal hexa-histidine tagged human cloned Eg5 (1 to 368 amino acids) expressed in Escherichia coli BL21 (DE3) assessed as reduction...More data for this Ligand-Target Pair