Affinity DataIC50: 24nMAssay Description:Inhibition of PKCepsilonChecked by AuthorMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sunchon National University
Curated by ChEMBL
Sunchon National University
Curated by ChEMBL
Affinity DataIC50: 550nMAssay Description:Inhibition of recombinant human MAO-A using kynuramine as substrate incubated for 20 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Vitae Pharmaceuticals
Curated by ChEMBL
Vitae Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 566nMAssay Description:Binding affinity to human 6xHis-tagged PPARgamma ligand binding domain (206 to 477 residues) by TR-FRET assayMore data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
University Of Chemistry And Technology Prague
Curated by ChEMBL
University Of Chemistry And Technology Prague
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of rabbit skeletal muscle microsomes SERCA1a incubated for 10 mins by enzyme-coupled methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of AChE (unknown origin) preincubated for 30 mins followed by substrate addition acetylthiocholineiodide measured after 40 mins by Ellman'...More data for this Ligand-Target Pair
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of human AChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Abo Akademi University
Curated by ChEMBL
Abo Akademi University
Curated by ChEMBL
Affinity DataIC50: 3.78E+3nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 6.33E+3nMAssay Description:Inhibition of horse BChE by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 8.58E+3nMAssay Description:Inhibition of BuChE (unknown origin) preincubated for 30 mins followed by substrate addition acetylthiocholineiodide measured after 40 mins by Ellman...More data for this Ligand-Target Pair
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of human BChE by Ellman's methodMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sunchon National University
Curated by ChEMBL
Sunchon National University
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant human MAO-B using benzylamine as substrate incubated for 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Homo sapiens (Human))
University Of Chemistry And Technology Prague
Curated by ChEMBL
University Of Chemistry And Technology Prague
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of SERCA1a (unknown origin) incubated for 10 mins by enzyme-coupled methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:In the fluorescence polarization assay, the Bcl-XL protein is incubated with a fluorescein-tagged Bak-BH3 peptide. The Bcl-XL:Bak-BH3 peptide complex...More data for this Ligand-Target Pair
TargetRas-related C3 botulinum toxin substrate 1(Homo sapiens (Human))
Exonhit Therapeutics
Curated by ChEMBL
Exonhit Therapeutics
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Rac1 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Exonhit Therapeutics
Curated by ChEMBL
Exonhit Therapeutics
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
Affinity DataIC50: <5.74E+5nMAssay Description:Inhibition of HIV1 RTMore data for this Ligand-Target Pair
TargetAromatic-L-amino-acid decarboxylase(Homo sapiens (Human))
Hunan Agricultural University
Curated by ChEMBL
Hunan Agricultural University
Curated by ChEMBL
Affinity DataIC50: 1.28E+6nMAssay Description:Inhibition of recombinant human DOPA decarboxylase assessed as inhibition of dopamine production after 30 mins by HPLC methodMore data for this Ligand-Target Pair