TargetMitogen-activated protein kinase kinase kinase kinase 5(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of MAP4K5More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Yes(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
TargetTyrosine-protein kinase ABL2(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
University Of Edinburgh
Curated by ChEMBL
University Of Edinburgh
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human BMX using poly(Glu,Tyr) 4:1 as substrate after 40 mins by scintillation counting analysis in presence of [gamma-33P-ATP]More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human SRC (1 to 530 residues) using GGEEEEYFELVKKKK as substrate after 40 mins by scintillation counting analysis in presence of [gamma...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human ABL using EAIYAAPFAKKK as substrate after 40 mins by scintillation counting analysis in presence of [gamma-33P-ATP]More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
University Of Edinburgh
Curated by ChEMBL
University Of Edinburgh
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human MEK1 after 40 mins in presence of MgATPMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of c-Abl (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of wild type AblMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fgr(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibitory concentration against v-Abl tyrosine kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Abl kinaseMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Src kinase (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of cSrc (unknown origin) by ELISAMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.20nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.20nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human recombinant cSrc by ELISAMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Src protein tryrosine kinase dependent cellular proliferationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Hangzhou Medical College
Curated by ChEMBL
Hangzhou Medical College
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of BCR-ABL (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of cSrc (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Refer to Reaction Biology Corps.More data for this Ligand-Target Pair
TargetTyrosine-protein kinase FRK(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 3.60nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 3.80nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 3.80nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 3.80nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant human Src kinaseMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibitory concentration against Src kinaseMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human recombinant Src after 70 mins by FRET assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institut De Recherches Servier
Curated by ChEMBL
Institut De Recherches Servier
Curated by ChEMBL
TargetSerine/threonine-protein kinase 24(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
TargetTyrosine-protein kinase Blk(Mus musculus)
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 7.30nMAssay Description:Inhibition of mouse BLKMore data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
University Of Edinburgh
Curated by ChEMBL
University Of Edinburgh
Curated by ChEMBL
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL
Center For Molecular Medicine Of The Austrian Academy Of Sciences
Curated by ChEMBL