TargetMuscarinic acetylcholine receptor M1/M2/M3/M4/M5(Mus musculus)
Sri International
Curated by ChEMBL
Sri International
Curated by ChEMBL
Affinity DataIC50: 1.70E+5nMAssay Description:Compound was tested for the binding affinity towards muscarinic receptor in mouse brain membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1.85E+5nMAssay Description:Compound was tested for the competitive inhibition of acetylcholinesterase (AChE)More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sri International
Curated by ChEMBL
Sri International
Curated by ChEMBL
Affinity DataIC50: 1.85E+5nMAssay Description:Inhibition of eel acetylcholinesterase (AChE) activity by 50% More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+5nMAssay Description:Reversible inhibition of Human AchEMore data for this Ligand-Target Pair
Affinity DataIC50: 3.46E+5nMAssay Description:Inhibition of acetylcholinesterase (AChE) in bovine erythrocyte(RBC)More data for this Ligand-Target Pair
Affinity DataIC50: 3.66E+5nMAssay Description:Reversible inhibition of acetylcholinesterase(AChE) by 50 % in human erythrocytes More data for this Ligand-Target Pair
Affinity DataIC50: 3.66E+5nMAssay Description:In vitro concentration of compound required for reversibly inhibiting 50% of human anticholinesterase activityMore data for this Ligand-Target Pair
Affinity DataIC50: 3.66E+5nMAssay Description:Concentration required to inhibit 50% of acetylcholinesterase (AChE) in human erythrocyte(RBC).More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Sri International
Curated by ChEMBL
Sri International
Curated by ChEMBL
Affinity DataIC50: 4.00E+5nMAssay Description:In vitro reversible inhibition of eel acetylcholinesterase.More data for this Ligand-Target Pair
Affinity DataIC50: 8.78E+5nMAssay Description:Inhibition of human recombinant AChE by modified Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: 8.78E+5nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 9.96E+5nMAssay Description:Inhibition of human AChE assessed as decrease in enzyme activity incubated for 30 mins by Ellman's methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+6nMAssay Description:In vitro reversible inhibition of eel acetylcholinesterase.More data for this Ligand-Target Pair
Affinity DataIC50: 1.19E+6nMAssay Description:Inhibition of hemoglobin free human erythrocyte ghost acetylcholinesterase using acetylthiocholineiodide as substrate measured up to 1 hr by Ellman m...More data for this Ligand-Target Pair
Affinity DataIC50: 1.21E+6nMAssay Description:Inhibition of hemoglobin free erythrocyte ghost human AChE using acetylcholine iodide as substrate measured for 1 hr by spectrophotometry based Ellma...More data for this Ligand-Target Pair