Affinity DataIC50: 0.200nMAssay Description:Inhibition of wild type EGFR (unknown origin) incubated for 5 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMAssay Description:Inhibition of wild type EGFR T790M mutant (unknown origin) incubated for 5 mins by HTRF assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-4(Homo sapiens (Human))
Zhejiang University
Curated by ChEMBL
Zhejiang University
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of wild type HER4 (unknown origin) incubated for 5 mins by HTRF assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Zhejiang University
Curated by ChEMBL
Zhejiang University
Curated by ChEMBL
Affinity DataIC50: 75nMAssay Description:Inhibition of wild type HER2 (unknown origin) incubated for 5 mins by HTRF assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Zhejiang University
Curated by ChEMBL
Zhejiang University
Curated by ChEMBL
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of wild type SRC (unknown origin) incubated for 5 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Zhejiang University
Curated by ChEMBL
Zhejiang University
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of wild type PDGFRbeta (unknown origin) incubated for 5 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.26E+3nMAssay Description:Inhibition of wild type ABL (unknown origin) incubated for 5 mins by HTRF assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Zhejiang University
Curated by ChEMBL
Zhejiang University
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of wild type PDGFRalpha (unknown origin) incubated for 5 mins by HTRF assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Zhejiang University
Curated by ChEMBL
Zhejiang University
Curated by ChEMBL
Affinity DataIC50: 6.81E+3nMAssay Description:Inhibition of wild type FLT3 (unknown origin) incubated for 5 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of wild type SYK (unknown origin) incubated for 5 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of wild type JAK2 (unknown origin) incubated for 5 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of wild type ALK (unknown origin) incubated for 5 mins by HTRF assayMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University
Curated by ChEMBL
Zhejiang University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of wild type AKT1 (unknown origin) incubated for 5 mins by HTRF assayMore data for this Ligand-Target Pair
TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Zhejiang University
Curated by ChEMBL
Zhejiang University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of wild type AKT2 (unknown origin) incubated for 5 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of wild type c-Met (unknown origin) incubated for 5 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of wild type FGFR2 (unknown origin) incubated for 5 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 in human hepatic microsomes after 20 mins by LC/MS/MS methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 in human hepatic microsomes after 20 mins by LC/MS/MS methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 in human hepatic microsomes after 20 mins by LC/MS/MS methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19 in human hepatic microsomes after 20 mins by LC/MS/MS methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2 in human hepatic microsomes after 20 mins by LC/MS/MS methodMore data for this Ligand-Target Pair