TargetUrease subunit beta(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Wroc?Aw University Of Technology
Curated by ChEMBL
Wroc?Aw University Of Technology
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of Helicobacter pylori ATCC 43504 urease assessed as amount of ammonia after 15 mins by indophenol methodMore data for this Ligand-Target Pair
TargetCytosolic endo-beta-N-acetylglucosaminidase(Homo sapiens (Human))
University Of Utah
Curated by ChEMBL
University Of Utah
Curated by ChEMBL
Affinity DataIC50: 4.47E+3nMAssay Description:Inhibition of recombinant human C-MYC/DDK-tagged ENGase expressed in HEK293T cells using heat inactivated bovine ribonuclease B as substrate pretreat...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Federal University Of Parana
Curated by ChEMBL
Federal University Of Parana
Curated by ChEMBL
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of human ABCG2 expressed in human HEK293 cells membrane vesicles mediated transport of 3[H]-MTX for 2 mins using [3H]-methotrexate as subs...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human recombinant IDE expressed in Escherichia coli BL21 (DE3) cells using ATTO 655- Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substra...More data for this Ligand-Target Pair
TargetFatty acid synthase(Homo sapiens (Human))
Indiana University School Of Medicine
Curated by ChEMBL
Indiana University School Of Medicine
Curated by ChEMBL
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of purified recombinant FASN TE activity (unknown origin) using 4-MUH as substrate preincubated for 30 mins before substrate addition meas...More data for this Ligand-Target Pair
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Homo sapiens (Human))
Univ. Lille
Curated by ChEMBL
Univ. Lille
Curated by ChEMBL
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of human recombinant DDAH1 reduction in L-citrulline formation using ADMA as substrateMore data for this Ligand-Target Pair