Found 102 of ec50 for monomerid = 50072775 
Affinity DataEC50: 19.9nMAssay Description:Agonist activity at human cannabinoid CB1 receptor expressed in CHO cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 0.350nMAssay Description:Agonist activity at human CB2 receptor expressed in CHOK1 cells assessed as reversal of forskolin-evoked cAMP accumulationMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 2.40nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40nMAssay Description:Agonist activity at human recombinant CB1 receptor expressed in CHO cell membranes by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 41nMAssay Description:Agonist activity at human CB2 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP by scint...More data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Agonist activity at human CB1 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP by scint...More data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Agonist activity at human CB1 receptor expressed in Sf9 cells coexpressing Gbeta1gamma2 and RSG4 assessed as degradation of [gamma-33P]GTP after 20 m...More data for this Ligand-Target Pair
Affinity DataEC50: 12.9nMAssay Description:Agonist activity at human CB1 receptor expressed in Sf9 cells coexpressing Gbeta1gamma2 and RSG4 assessed as degradation of [gamma-33P]GTP after 20 m...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 9.30nMAssay Description:Partial agonist activity at human cannabinoid CB2 receptor expressed in CHO-K1 cells assessed as [S35]GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 3.90nMAssay Description:Partial agonist activity at human cannabinoid CB1 receptor expressed in CHO-K1 cells assessed as [S35]GTPgammaS binding by scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Agonist activity at CB1 receptor (unknown origin) expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 26nMAssay Description:Agonist activity at CB2 receptor (unknown origin) expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 31nMAssay Description:Agonist activity at CB2R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...More data for this Ligand-Target Pair
Affinity DataEC50: 7.90nMAssay Description:Agonist activity at CB1R (unknown origin) CHO cells stably expressing Galpha16 assessed as increase in intracellular calcium level by microplate read...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 0.576nMAssay Description:Activity at hemagglutinin-tagged human CB1 receptor expressed in HEK293 cells assessed as effect on forskolin-induced cAMP accumulation in presence o...More data for this Ligand-Target Pair
Affinity DataEC50: 0.437nMAssay Description:Activity at hemagglutinin-tagged human CB1 receptor expressed in HEK293 cells assessed as effect on forskolin-induced cAMP accumulation in presence o...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 6.10nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells assessed as stimulation of [35S]-GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 42nMAssay Description:Agonist activity at MF1 mouse brain CB1 receptor assessed as induction of [35S]GTPgammaS binding after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 6.10nMAssay Description:Effect on [35S]GTP-gamma-S binding to human CB2 receptorMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation using [3H]-cAMP after ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.28nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation using [3H]-cAMP after ...More data for this Ligand-Target Pair
Affinity DataEC50: 0.280nMAssay Description:Agonist activity at human CB1 receptor expressed in HEK293 cells assessed as reversal of forskolin-evoked cAMP accumulationMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 0.860nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 47nMAssay Description:Inverse agonist activity at human CB2 receptor expressed in CHO cells assessed as increase in forskolin-induced cAMP production after 45 mins in pres...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Agonist activity at recombinant human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 5 mins ...More data for this Ligand-Target Pair
Affinity DataEC50: 2.30nMAssay Description:Agonist activity at recombinant human CB1 receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 5 mins ...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 11nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes assessed as increase in forskolin-stimulated cAMP production after 45 mins by ...More data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cells by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 2.70nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 10.3nMAssay Description:Inverse agonist activity at human recombinant CB1 receptor expressed CHO cells membrane by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 8.66nMAssay Description:Inverse agonist activity at human recombinant CB2 receptor expressed CHO cells membrane by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.28nMAssay Description:Agonist activity at human CB1 receptor expressed in Sf9 cells by GTP-europium binding assayMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 0.430nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in Sf9 cells by GTP-europium binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.260nMAssay Description:Agonist activity at human recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 0.880nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: 0.160nMAssay Description:Agonist activity at rat recombinant CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: 0.340nMAssay Description:Agonist activity at rat recombinant CB2 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-stimulated intracellular cAMP levelMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 0.690nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 0.860nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 7.40nMAssay Description:Agonist activity at human CB2 receptor transfected in CHO cell membranes by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.700nMAssay Description:Agonist activity at human CB1 receptor transfected in CHO cell membranes by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Agonist activity at CB1 receptor (unknown origin) expressed in CHO cells assessed as induction of calcium mobilization by fluo-4 AM dye-based fluores...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 29nMAssay Description:Agonist activity at CB2 receptor (unknown origin) expressed in CHO cells assessed as induction of calcium mobilization by fluo-4 AM dye-based fluores...More data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Agonist activity at CB1 receptor (unknown origin) expressed in CHO cells co-expressing G-alpha16 incubated for 24 hrs by fluo-4 AM dye based whole-ce...More data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 29nMAssay Description:Agonist activity at CB2 receptor (unknown origin) expressed in CHO cells co-expressing G-alpha16 incubated for 24 hrs by fluo-4 AM dye based whole-ce...More data for this Ligand-Target Pair
Affinity DataEC50: 5.5nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 5.5nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cell membranes after 90 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Agonist activity at recombinant rat Cb1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP levelsMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 2nMAssay Description:Agonist activity at recombinant human Cb2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP levelsMore data for this Ligand-Target Pair
TargetCannabinoid receptor 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 1.70nMAssay Description:Agonist activity at N-terminal FLAG-tagged human CB2 receptor transfected in human HTLA cells assessed as induction of beta-arrestin-recruitment afte...More data for this Ligand-Target Pair
