Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Binding affinity for displacement of [3H]ketanserin to rat 5-hydroxytryptamine 2A receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Toronto
Curated by PDSP Ki Database
University Of Toronto
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Toronto
Curated by PDSP Ki Database
University Of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.300nMAssay Description:Ability of the compound to displace [H]-ketanserin from CHO cells expressing human 5-hydroxytryptamine 2A receptor was determinedMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Toronto
Curated by PDSP Ki Database
University Of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.310nMAssay Description:Displacement of [3H]- ketanserin from human 5HT2A receptor expressed CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Toronto
Curated by PDSP Ki Database
University Of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.310nMAssay Description:Binding affinity for displacement of [3H]ketanserin to human 5-hydroxytryptamine 2A receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Toronto
Curated by PDSP Ki Database
University Of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.360nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor in humansMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.360nMAssay Description:Displacement of [3H]MDL100907 from rat cortical membrane 5HT2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 0.380nMAssay Description:Displacement of [3H]MDL from rat 5HT2A receptor expressed in GF62 cells by liquid scintillation analyserMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Toronto
Curated by PDSP Ki Database
University Of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 0.570nMAssay Description:Binding affinity to 5HT2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Binding affinity towards rat 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Toronto
Curated by PDSP Ki Database
University Of Toronto
Curated by PDSP Ki Database
Affinity DataKi: 1.5nMAssay Description:Binding affinity for human 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Displacement of [3H]MDL from rat 5HT2A receptor expressed in GF62 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Displacement of [3H]-mesulergine from human 5HT2C receptor expressed CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Binding affinity for displacement of [3H]mesulergine to human 5-hydroxytryptamine 2C receptor stably expressed in CHO cellsMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(RAT)
Hoechst Marion Roussel
Curated by PDSP Ki Database
Hoechst Marion Roussel
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Hoechst Marion Roussel
Curated by PDSP Ki Database
Hoechst Marion Roussel
Curated by PDSP Ki Database
Affinity DataKi: 107nMAssay Description:Binding affinity to 5HT2C receptor (unknown origin) by competitive binding experimentMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Hoechst Marion Roussel
Curated by PDSP Ki Database
Hoechst Marion Roussel
Curated by PDSP Ki Database
Affinity DataKi: 1.00E+3nMAssay Description:Antagonist activity against human histamine H1 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 1(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.06E+3nMAssay Description:Binding affinity at Voltage-gated potassium channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme
Curated by ChEMBL
Merck Sharp & Dohme
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Displacement of [3H]-dofetilide from human ERG receptor expressed HEK cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme
Curated by ChEMBL
Merck Sharp & Dohme
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Binding affinity against human IKr channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme
Curated by ChEMBL
Merck Sharp & Dohme
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Sharp & Dohme
Curated by ChEMBL
Merck Sharp & Dohme
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Displacement of [3H]-dofetilide to HEK cells stably expressing hERG voltage-gated IKr potassium channel Kv11.1More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.30E+3nMAssay Description:Binding affinity for displacement of [3H]spiperone to human dopamine D2 (hD2) receptors stably expressed in CHO cellsMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.30E+3nMAssay Description:Ability of the compound to displace [3H]-spiperone from CHO cells expressing human Dopamine receptor D2 was determinedMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Affinity DataKi: 2.25E+3nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin) by competitive binding experimentMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Hoechst Marion Roussel
Curated by PDSP Ki Database
Hoechst Marion Roussel
Curated by PDSP Ki Database
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Hoechst Marion Roussel
Curated by PDSP Ki Database
Hoechst Marion Roussel
Curated by PDSP Ki Database
TargetD(2) dopamine receptor(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp And Dohme Research Laboratories
Curated by ChEMBL
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Institute Of Nuclear Chemistry Johannes Gutenberg-University Mainz
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to 5-HT1A receptor (unknown origin) by competitive binding experimentMore data for this Ligand-Target Pair
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Hoechst Marion Roussel
Curated by PDSP Ki Database
Hoechst Marion Roussel
Curated by PDSP Ki Database