Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 0.603nMAssay Description:Binding affinity to 5-hydroxytryptamine 3 receptor entirely in guinea pig ileumMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:In vitro displacement of [3H]-LY 278584 from rat cerebral cortex 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:pKi value for inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 3 receptor in rat cortical membranes using [3H]- 1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-a...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:In vitro by displacement of [3H]LY-278584 from 5-hydroxytryptamine 3 receptor on rat entorhinal cortexMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Binding affinity towards rat 5-hydroxytryptamine 3 receptor was evaluatedMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:In vitro affinity for 5-hydroxytryptamine 3 (5-HT3) receptor by displacement of [3H]BRL-43694 from rat entorhinal cortexMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortexMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor in rat brain cortical membranes using radioligand [3H]quipazineChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:In vitro binding affinity for the 5-hydroxytryptamine 3 receptor was determined with NG-108-15 mouse neuroblastoma-glioma cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:In vitro inhibition of rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor by displacement of [3H]2 in Neuroblastoma-Glioma NG-108-15 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Binding affinity at 5HT3 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 3.20nMAssay Description:Compound was evaluated for its binding affinity for 5-hydroxytryptamine 3 receptor by measuring displacement [3H]GR-65630 in rat cerebral cortexMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 3.20nMAssay Description:Binding affinity to 5-hydroxytryptamine 3 receptor of neuronal in the afferent rabbit vagusMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merrell Dow Research Institute
Curated by ChEMBL
Merrell Dow Research Institute
Curated by ChEMBL
Affinity DataKi: 3.80nMAssay Description:Displacement of binding of [3H]-BRL 43694 to 5-hydroxytryptamine 3 receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:The binding affinity was measured for 5-hydroxytryptamine 3 receptor on NG 108-15 cell line of mouse neuroblastoma-glioma cells in presence of [3H]5 ...More data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Inhibition of 5HT3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Inhibition constant against 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Organon Laboratories
Curated by ChEMBL
Organon Laboratories
Curated by ChEMBL
Affinity DataKi: 6.90nMAssay Description:Inhibition constant against nicotinic acetylcholine receptor alpha7More data for this Ligand-Target Pair
Affinity DataKi: 6.90nMAssay Description:In vitro Binding affinity towards alpha-7 nAChR was determinedMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Organon Laboratories
Curated by ChEMBL
Organon Laboratories
Curated by ChEMBL
Affinity DataKi: 6.90nMAssay Description:Binding affinity to alpha7 nAChRMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Homo sapiens (Human))
Cooperation Pharmaceutique Fran�Aise
Curated by ChEMBL
Cooperation Pharmaceutique Fran�Aise
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:Binding affinity of compound towards 5-hydroxytryptamine 3 receptor using [3H]-BRL-43694 (1 nM) ligand in NG cells 108-15 was determinedMore data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Displacement of [3H]GR-113808 from rat striatum 5-hydroxytryptamine 4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 125nMAssay Description:Binding affinity towards 5-hydroxytryptamine 4 receptor in striatum membranes of guinea-pig brain was evaluatedMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of binding of [3H]-5-HT to 5-hydroxytryptamine 1 receptor in rat cerebral cortexMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataKi: 1.60E+4nMAssay Description:In vitro Binding affinity towards alpha-3 (PC12) nAChR was determinedMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataKi: 2.70E+4nMAssay Description:In vitro Binding affinity towards alpha-1-beta-1-gamma delta nAChR was determinedMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataKi: 5.50E+4nMAssay Description:In vitro Binding affinity towards 5-hydroxytryptamine 3 receptor was determinedMore data for this Ligand-Target Pair