TargetHistamine H1 receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Inhibition of [3H]-pyrilamine binding to human Histamine H1 receptor More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2A receptor was determined using [3H]-ketanserinMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 5.5nMAssay Description:The binding affinity of the compound at 5-hydroxytryptamine 2C receptor was determined using [3H]-mesulergineMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 8.20nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 14.8nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor by displacement of [3H]ketanserin from rat prefrontal cerebral cortex mambranesMore data for this Ligand-Target Pair
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Inhibition of [3H]-rauwolscine binding to Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: >18nMAssay Description:The binding affinity of the compound at the 5-hydroxytryptamine 1A receptor determined using [3H]-5-CTMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Binding affinity to human 5HT1A receptorMore data for this Ligand-Target Pair
Affinity DataKi: >20nMAssay Description:The binding affinity of the compound at the Dopamine receptor D3 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of [3H]-rauwolscine binding to Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: >25nMAssay Description:The binding affinity of the compound at the Dopamine receptor D4 determined using [3H]-YM-09151-2More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 39nMAssay Description:Inhibition of [3H]-mesulergine binding to human 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Jagiellonian University Medical College
Curated by ChEMBL
Jagiellonian University Medical College
Curated by ChEMBL
Affinity DataKi: 69nMAssay Description:Inhibition of [125I]-R91150 binding to human 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 265nMAssay Description:Inhibition of [3H]-5-HT binding to human 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Organon International
Curated by PDSP Ki Database
Organon International
Curated by PDSP Ki Database
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Organon International
Curated by PDSP Ki Database
Organon International
Curated by PDSP Ki Database
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
Affinity DataKi: 1.46E+3nMAssay Description:The binding affinity of the compound at the Dopamine receptor D2 determined using [3H]-spiperoneMore data for this Ligand-Target Pair
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
Organon International
Curated by PDSP Ki Database
Organon International
Curated by PDSP Ki Database
TargetTransporter(Rattus norvegicus)
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 1.64E+3nMAssay Description:Inhibition of [3H]-nisoxetine binding to rat Norepinephrine transpoterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic
Curated by PDSP Ki Database
Mayo Clinic
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 2.90E+3nMAssay Description:Displacement of [3H]GR65630 from human 5-HT3A receptor expressed in HEK293 cells by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
TargetD(1A) dopamine receptor(RAT)
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: 4.17E+3nMAssay Description:Inhibition of [3H]-SCH-23,390 binding to rat Dopamine receptor D1More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic
Curated by PDSP Ki Database
Mayo Clinic
Curated by PDSP Ki Database
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
University Center For Pharmacy
Curated by ChEMBL
University Center For Pharmacy
Curated by ChEMBL
TargetD(2) dopamine receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
Affinity DataKi: >5.45E+3nMAssay Description:Inhibition of [3H]-spiperone binding to human Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 5.72E+3nMAssay Description:Inhibition of [125I]-iodosulpride binding to human Dopamine receptor D3More data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Organon International
Curated by PDSP Ki Database
Organon International
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Organon International
Curated by PDSP Ki Database
Organon International
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Organon International
Curated by PDSP Ki Database
Organon International
Curated by PDSP Ki Database
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Mayo Clinic
Curated by PDSP Ki Database
Mayo Clinic
Curated by PDSP Ki Database
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Mayo Clinic
Curated by PDSP Ki Database
Mayo Clinic
Curated by PDSP Ki Database
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Mayo Clinic
Curated by PDSP Ki Database
Mayo Clinic
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Mayo Clinic
Curated by PDSP Ki Database
Mayo Clinic
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Mayo Clinic
Curated by PDSP Ki Database
Mayo Clinic
Curated by PDSP Ki Database